公开(公告)号：US11820979B2

公开(公告)日：2023-11-21

申请号：US15852718

申请日：2017-12-22

申请人： VISTERRA, INC.

发明人： Zachary Shriver ,  Gregory Babcock ,  Luke Robinson

IPC分类号： C12N15/10 ,  C07K16/18 ,  C07K16/00

CPC分类号： C12N15/1093 ,  C07K16/00 ,  C07K16/005 ,  C07K16/18 ,  C07K2317/10 ,  C07K2317/56 ,  C07K2317/622

摘要： Polypeptides, such as antibody molecules and TCR molecules, and methods of making the same, are disclosed. The polypeptides can be used to treat, prevent, and/or diagnose disorders.

公开(公告)号：US11773179B2

公开(公告)日：2023-10-03

申请号：US17147842

申请日：2021-01-13

申请人： Visterra, Inc.

发明人： Karthik Viswanathan ,  Brian Booth ,  Boopathy Ramakrishnan ,  Andrew Wollacott ,  Gregory Babcock ,  Zachary Shriver

IPC分类号： C07K16/28 ,  A61K39/00

CPC分类号： C07K16/2896 ,  A61K2039/505 ,  C07K2317/31 ,  C07K2317/76

摘要： Antibody molecules that specifically bind to C5aR1 are disclosed. The antibody molecules can be used to treat, prevent, and/or diagnose disorders, such as ANCA-vasculitis.

公开(公告)号：US10981982B2

公开(公告)日：2021-04-20

申请号：US16912085

申请日：2020-06-25

申请人： VISTERRA, INC.

发明人： James R. Myette ,  Zachary Holmes Shriver ,  Karthik Viswanathan ,  Andrew M. Wollacott ,  Hedy Adari-Hall ,  Boopathy Ramakrishnan ,  Gregory Babcock

IPC分类号： C07K16/24 ,  C07K16/28 ,  A61K39/395 ,  A61K45/06 ,  A61K39/00

摘要： Antibody molecules that specifically bind to APRIL are disclosed. The antibody molecules can be used to treat, prevent, and/or diagnose disorders, such as IgA nephropathy.

公开(公告)号：US10954296B2

公开(公告)日：2021-03-23

申请号：US16898024

申请日：2020-06-10

申请人： VISTERRA, INC.

发明人： James R. Myette ,  Zachary Holmes Shriver ,  Karthik Viswanathan ,  Andrew M. Wollacott ,  Hedy Adari-Hall ,  Boopathy Ramakrishnan ,  Gregory Babcock

IPC分类号： A61K39/395 ,  A61K39/00 ,  C07K16/24 ,  A61K45/06 ,  C07K16/28

摘要： Antibody molecules that specifically bind to APRIL are disclosed. The antibody molecules can be used to treat, prevent, and/or diagnose disorders, such as IgA nephropathy.

公开(公告)号：US20200331995A1

公开(公告)日：2020-10-22

申请号：US16912131

申请日：2020-06-25

申请人： VISTERRA, INC.

发明人： James R. Myette ,  Zachary Holmes Shriver ,  Karthik Viswanathan ,  Andrew M. Wollacott ,  Hedy Adari-Hall ,  Boopathy Ramakrishnan ,  Gregory Babcock

IPC分类号： C07K16/24 ,  A61K39/395 ,  A61K45/06 ,  C07K16/28

摘要： Antibody molecules that specifically bind to APRIL are disclosed. The antibody molecules can be used to treat, prevent, and/or diagnose disorders, such as IgA nephropathy.

公开(公告)号：US20230257449A1

公开(公告)日：2023-08-17

申请号：US17783966

申请日：2020-12-11

申请人： VISTERRA, INC.

发明人： Karthik Viswanathan ,  Brian Booth ,  Boopathy Ramakrishnan ,  Andrew M. Wollacott ,  Gregory Babcock ,  Zachary Shriver

IPC分类号： C07K16/10 ,  C12N15/63 ,  A61P31/16

CPC分类号： C07K16/1018 ,  A61P31/16 ,  C12N15/63 ,  A61K2039/505 ,  C07K2317/52 ,  C07K2317/565

摘要： This disclosure relates to binding agents, e.g., antibody molecules, that bind hemagglutinin protein of influenza viruses, and methods of their use.

公开(公告)号：US20220177553A1

公开(公告)日：2022-06-09

申请号：US17369410

申请日：2021-07-07

申请人： VISTERRA, INC.

发明人： Luke Robinson ,  Zachary Shriver ,  James R. Myette ,  Gregory Babcock ,  Karthik Viswanathan

IPC分类号： C07K16/10 ,  G01N33/569 ,  A61K39/42 ,  A61K45/06

摘要： Antibody molecules that specifically bind to dengue virus are disclosed. In certain embodiments, the antibody molecule bind to dengue virus serotypes DV-1, DV-2, DV-3, and DV-4. The antibody molecules can be used to treat, prevent, and/or diagnose dengue virus.

公开(公告)号：US20220177535A1

公开(公告)日：2022-06-09

申请号：US17541989

申请日：2021-12-03

申请人： VISTERRA, INC. ,  THE GENERAL HOSPITAL CORPORATION

发明人： Scott Moore Carlson ,  Gregory Babcock ,  Zachary Shriver ,  Boopathy Ramakrishnan ,  Thiago de Jesus Borges ,  Leonardo Vidal Riella

IPC分类号： C07K14/55 ,  A61K45/06 ,  A61P13/12 ,  A61P37/06

摘要： IL-2 agents that comprise IL-2 variants are disclosed as well as methods, compositions, and uses thereof. The IL-2 agents described herein can be used to treat and/or prevent various disorders and conditions.

公开(公告)号：US20220089764A1

公开(公告)日：2022-03-24

申请号：US17147842

申请日：2021-01-13

申请人： Visterra, Inc.

发明人： Karthik Viswanathan ,  Brian Booth ,  Boopathy Ramakrishnan ,  Andrew Wollacott ,  Gregory Babcock ,  Zachary Shriver

IPC分类号： C07K16/28

摘要： Antibody molecules that specifically bind to C5aR1 are disclosed. The antibody molecules can be used to treat, prevent, and/or diagnose disorders, such as ANCA-vasculitis.

公开(公告)号：US11136385B2

公开(公告)日：2021-10-05

申请号：US17074857

申请日：2020-10-20

申请人： VISTERRA, INC.

发明人： James R. Myette ,  Zachary Holmes Shriver ,  Karthik Viswanathan ,  Andrew M. Wollacott ,  Hedy Adari-Hall ,  Boopathy Ramakrishnan ,  Gregory Babcock

IPC分类号： C07K16/24 ,  A61K39/395 ,  A61K45/06 ,  C07K16/28 ,  A61K39/00

摘要： Antibody molecules that specifically bind to APRIL are disclosed. The antibody molecules can be used to treat, prevent, and/or diagnose disorders, such as IgA nephropathy.