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    Implantable electroacupuncture device and method for treating obesity
    3.
    发明授权
    Implantable electroacupuncture device and method for treating obesity 有权
    可植入电针装置及治疗肥胖症的方法

    公开(公告)号：US09364390B2

    公开(公告)日：2016-06-14

    申请号：US13736039

    申请日：2013-01-07

    申请人： Valencia Technologies Corporation

    发明人： Jeffrey H. Greiner ,  David K. L. Peterson ,  Chuladatta Thenuwara ,  Stacy O. Greiner

    IPC分类号： A61N1/375 ,  A61H39/00 ,  A61N1/372 ,  A61N1/00 ,  A61N1/36 ,  A61N1/32 ,  A61N1/378

    CPC分类号： A61H39/002 ,  A61H2201/01 ,  A61H2201/5005 ,  A61H2201/5038 ,  A61N1/32 ,  A61N1/36085 ,  A61N1/36089 ,  A61N1/36125 ,  A61N1/36153 ,  A61N1/36157 ,  A61N1/36175 ,  A61N1/37205 ,  A61N1/3756 ,  A61N1/3758 ,  A61N1/3782 ,  Y10T29/49208

    摘要： An implantable electroacupuncture device (IEAD) treats obese conditions of a patient through application of stimulation pulses applied at acupoints SP4, LR8 or ST40, or their underlying nerves saphenous and peroneal. The IEAD comprises an implantable, coin-sized, self-contained, leadless electroacupuncture device having at least two electrodes attached to an outside surface of its housing. The device generates stimulation pulses in accordance with a specified stimulation regimen. Power management circuitry within the device allows a primary battery, having a high internal impedance, to be used to power the device. The stimulation regimen generates stimulation pulses during a stimulation session of duration T3 minutes applied every T4 minutes. The duty cycle, or ratio T3/T4, is very low, no greater than 0.05. The low duty cycle and careful power management allow the IEAD to perform its intended function for several years.

    摘要翻译： 可植入电针装置（IEAD）通过施加在穴位SP4，LR8或ST40上施加的刺激脉冲或其潜伏的隐神经和腓神经来治疗患者的肥胖状况。 IEAD包括可植入的硬币大小的独立的无引线电针装置，其具有附接到其外壳的外表面的至少两个电极。 该设备根据指定的刺激方案产生刺激脉冲。 设备内的电源管理电路允许使用具有高内部阻抗的一次电池为设备供电。 刺激方案在每T4分钟施用持续时间T3分钟的刺激期间产生刺激脉冲。 占空比或比例T3 / T4非常低，不大于0.05。 低占空比和仔细的电源管理允许IEAD执行其预期功能几年。

    Implantable Electroacupuncture Device and Method for Treating Depression, Bipolar Disorder and Anxiety
    5.
    发明申请
    Implantable Electroacupuncture Device and Method for Treating Depression, Bipolar Disorder and Anxiety 有权
    植入式电针装置及治疗抑郁，双相障碍和焦虑的方法

    公开(公告)号：US20140214117A1

    公开(公告)日：2014-07-31

    申请号：US13630322

    申请日：2012-09-28

    申请人： VALENCIA TECHNOLOGIES CORPORATION

    发明人： Jeffrey H. Greiner ,  David K. L. Peterson ,  Chuladatta Thenuwara ,  Stacy O. Greiner

    IPC分类号： A61N1/36

    CPC分类号： A61H39/002 ,  A61N1/36096 ,  A61N1/36117 ,  A61N1/36125 ,  A61N1/36175 ,  A61N1/37205 ,  A61N1/3756 ,  A61N1/3782 ,  Y10T29/49002

    摘要： An implantable electroacupuncture device (IEAD) treats depression, bipolar disorder or Anxiety through application of stimulation pulses applied at acupoints GV20 and/or EXHN3. The IEAD comprises an implantable, coin-sized, self-contained, leadless electroacupuncture device having at least two electrodes attached to an outside surface of its housing. The device generates stimulation pulses in accordance with a specified stimulation regimen. Power management circuitry within the device allows a primary battery, having a high internal impedance, to be used to power the device. The stimulation regimen generates stimulation pulses during a stimulation session of duration T3 minutes applied every T4 minutes. The duty cycle, or ratio T3/T4, is very low, no greater than 0.05. The low duty cycle and careful power management allow the IEAD to perform its intended function for several years.

    摘要翻译： 可植入电针装置（IEAD）通过施加在穴位GV20和/或EXHN3处施加的刺激脉冲来治疗抑郁症，双相情感障碍或焦虑症。 IEAD包括可植入的硬币大小的独立的无引线电针装置，其具有附接到其外壳的外表面的至少两个电极。 该设备根据指定的刺激方案产生刺激脉冲。 设备内的电源管理电路允许使用具有高内部阻抗的一次电池为设备供电。 刺激方案在每T4分钟施用持续时间T3分钟的刺激期间产生刺激脉冲。 占空比或比例T3 / T4非常低，不大于0.05。 低占空比和仔细的电源管理允许IEAD执行其预期功能几年。

    Implantable electroacupuncture system and method for treating dyslipidemia and obesity
    7.
    发明授权
    Implantable electroacupuncture system and method for treating dyslipidemia and obesity 有权
    植入式电针系统及治疗血脂异常和肥胖的方法

    公开(公告)号：US09314399B2

    公开(公告)日：2016-04-19

    申请号：US13736033

    申请日：2013-01-07

    申请人： Valencia Technologies Corporation

    发明人： Jeffrey H. Greiner ,  David K. L. Peterson ,  Chuladatta Thenuwara ,  Stacy O. Greiner

    IPC分类号： A61N1/375 ,  A61H39/00 ,  A61N1/36 ,  A61N1/372 ,  A61N1/378

    CPC分类号： A61H39/002 ,  A61F5/0026 ,  A61H2201/50 ,  A61H2201/5005 ,  A61H2201/5038 ,  A61H2201/5097 ,  A61N1/36085 ,  A61N1/36117 ,  A61N1/36125 ,  A61N1/36153 ,  A61N1/36157 ,  A61N1/36175 ,  A61N1/37205 ,  A61N1/375 ,  A61N1/3756 ,  A61N1/3758 ,  A61N1/3782 ,  Y10T29/49117

    摘要： An Implantable ElectroAcupuncture System (IEAS) treats dyslipidemia or obesity through application of stimulation pulses applied at at least one of acupoints ST36, SP4, ST37, ST40, SP6, SP9, K16, or LR8, or underlying nerves saphenous or peroneal. The IEAS includes an hermetically-sealed implantable electroacupuncture (EA) device having at least two electrodes located outside of its housing. The housing contains a primary power source, pulse generation circuitry, and a sensor that wirelessly senses externally-generated operating commands. The pulse generation circuitry generates stimulation pulses as controlled, at least in part, by the operating commands sensed through the sensor. The stimulation pulses are applied to the specified acupoint or nerve through the electrodes in accordance with a specified stimulation regimen. Such stimulation regimen requires that the stimulation session be applied at a very low duty cycle not greater than 0.05.

    摘要翻译： 可植入电针刺系统（IEAS）通过施加在穴位ST36，SP4，ST37，ST40，SP6，SP9，K16或LR8中的至少一个或隐匿性或腓神经的下面的神经施加刺激脉冲来治疗血脂异常或肥胖。 IEAS包括密封的可植入电针（EA）装置，其具有位于其壳体外部的至少两个电极。 外壳包含主电源，脉冲发生电路和无线感应外部生成的操作命令的传感器。 脉冲产生电路至少部分地通过通过传感器感测的操作命令来产生刺激脉冲。 刺激脉冲根据指定的刺激方案通过电极施加到指定的穴位或神经。 这种刺激方案要求在非常低的占空比不大于0.05的情况下施用刺激会话。

    Implantable Electroacupuncture Device and Method for Treating Obesity
    9.
    发明申请
    Implantable Electroacupuncture Device and Method for Treating Obesity 审中-公开
    植入式电针装置及治疗肥胖的方法

    公开(公告)号：US20160008222A1

    公开(公告)日：2016-01-14

    申请号：US14861839

    申请日：2015-09-22

    申请人： Valencia Technologies Corporation

    发明人： Jeffrey H. Greiner ,  David K. L. Peterson ,  Chuladatta Thenuwara ,  Stacy O. Greiner

    IPC分类号： A61H39/00

    CPC分类号： A61H39/002 ,  A61H2201/01 ,  A61H2201/5005 ,  A61H2201/5038 ,  A61N1/32 ,  A61N1/36085 ,  A61N1/36089 ,  A61N1/36125 ,  A61N1/36153 ,  A61N1/36157 ,  A61N1/36175 ,  A61N1/37205 ,  A61N1/3756 ,  A61N1/3758 ,  A61N1/3782 ,  Y10T29/49208

    摘要： An exemplary method for treating obesity in a patient comprising the steps of 1) implanting a coin-sized electroacupuncture (EA) device in the patient below the patient's skin at at least one specified stimulation site, 2) enabling the EA device to generate stimulation sessions at a duty cycle that is less than 0.05, each stimulation session comprising a series of stimulation pulses, wherein the duty cycle is the ratio of T3/T4, where T3 is the duration in minutes of each stimulation session, and T4 is the time in minutes between stimulation sessions, and 3) delivering the stimulation pulses of each stimulation session to the at least one specified stimulation site through at least two electrodes/arrays attached to an outside surface of the EA device.

    摘要翻译： 一种用于治疗患者肥胖症的示例性方法，包括以下步骤：1）在至少一个特定刺激部位的患者皮肤下的患者中植入硬币大小的电针（EA）装置，2）使得EA装置能够产生刺激会话 在小于0.05的占空比下，每个刺激会话包括一系列刺激脉冲，其中占空比是T3 / T4的比例，其中T3是每个刺激会话的持续时间（分钟），T4是 分钟，以及3）通过连接到EA设备的外表面的至少两个电极/阵列将每个刺激会话的刺激脉冲递送到至少一个指定的刺激部位。

    Stimulation paradigm to improve blood pressure dipping in an implantable electroacupuncture device
    10.
    发明授权
    Stimulation paradigm to improve blood pressure dipping in an implantable electroacupuncture device 有权
    刺激范式，以改善植入式电针装置中浸润的血压

    公开(公告)号：US08942808B2

    公开(公告)日：2015-01-27

    申请号：US13786447

    申请日：2013-03-05

    申请人： Valencia Technologies Corporation

    发明人： David K. L. Peterson ,  Stacy O. Greiner

    IPC分类号： A61N1/00 ,  A61B17/00 ,  A61N1/36

    CPC分类号： A61N1/36117 ,  A61H39/002 ,  A61H2201/5005 ,  A61H2201/5038 ,  A61H2201/5041 ,  A61H2201/5097 ,  A61N1/3605 ,  A61N1/36135 ,  A61N1/36175 ,  A61N1/37205 ,  A61N1/3756 ,  A61N1/3782

    摘要： A coin-sized implantable electroacupuncture (EA) device defines a stimulation paradigm, or stimulation regimen, that controls when EA stimulation pulses are applied to a selected acupoint, or other specified tissue location, to treat hypertension or nondipping. The stimulation regimen is applied when the patient is sleeping in order to minimize or mitigate the occurrence of nondipping or reverse dipping of the patient's blood pressure. In one embodiment, medical personnel, set a timing reference marker at the time of implant that defines how much time should elapse before a nighttime stimulation window opens that allows an EA stimulation session to be applied to the patient. In another embodiment, the patient sets the time when the nighttime stimulation window opens or when the EA stimulation session begins. Typically, an EA stimulation session is applied to the patient at a low duty cycle, e.g., only once a week during the nighttime.

    摘要翻译： 硬币大小的可植入电针（EA）装置定义了刺激范例或刺激方案，其控制何时将EA刺激脉冲施加到选定的穴位或其他指定的组织位置以治疗高血压或非浸润。 当患者睡觉时应用刺激方案以便最小化或减轻患者血压的非浸没或反浸渍的发生。 在一个实施例中，医务人员在植入时设置定时参考标记，其定义在夜间刺激窗口打开之前经过多少时间，其允许将EA刺激会话应用于患者。 在另一个实施例中，患者设定夜间刺激窗口打开或EA刺激会话开始时的时间。 通常，EA刺激会话以低工作周期应用于患者，例如在夜间仅每星期一次。