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1.发明授权公开(公告)号：US07514447B2
公开(公告)日：2009-04-07
申请号：US11535455
申请日：2006-09-26
申请人： Valentina Molteni , Xiaolin Li , Donatella Chianelli , Jon Loren , Juliet Nabakka , Xiadong Liu , Shifeng Pan , Yi Liu , Donald S. Karanewsky , Pascal Furet , Vito Guagnano , Shuli You
发明人： Valentina Molteni , Xiaolin Li , Donatella Chianelli , Jon Loren , Juliet Nabakka , Xiadong Liu , Shifeng Pan , Yi Liu , Donald S. Karanewsky , Pascal Furet , Vito Guagnano , Shuli You
IPC分类号： C07D239/42 , C07D403/10 , C07D403/14 , A61K31/505 , A61K31/506 , A61P35/00
CPC分类号： C07D403/04 , C07D239/42 , C07D401/12 , C07D403/12 , C07D405/12 , C07D409/04 , C07D413/12 , C07D417/12 , C07D471/04 , C07D491/10
摘要： Described herein are compounds that include a diarylamine structural feature. Also described herein are methods for making such compounds, methods for using such compounds to modulate the activity of c-kit receptors, and pharmaceutical compositions and medicaments comprising such compounds. Also described herein are methods of using such compounds, pharmaceutical compositions and medicaments to treat and/or prevent and/or inhibit and/or ameliorate the pathology and/or symptomology diseases or conditions associated with the activity of c-kit receptors.
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2.发明申请Diarylamine-Containing Compounds and Compositions, and their use as Modulators of C-Kit Receptors 有权含二芳基胺的化合物和组合物，以及它们作为C-Kit受体的调节剂的用途公开(公告)号：US20070149538A1
公开(公告)日：2007-06-28
申请号：US11535455
申请日：2006-09-26
申请人： Valentina Molteni , Xiaolin Li , Donatella Chianelli , Jon Loren , Shuli You , Juliet Nabakka , Xiadong Liu , Shifeng Pan , Yi Liu , Donald Karanewsky , Pascal Furet , Vito Guagnano
发明人： Valentina Molteni , Xiaolin Li , Donatella Chianelli , Jon Loren , Shuli You , Juliet Nabakka , Xiadong Liu , Shifeng Pan , Yi Liu , Donald Karanewsky , Pascal Furet , Vito Guagnano
IPC分类号： A61K31/496 , C07D403/02
CPC分类号： C07D403/04 , C07D239/42 , C07D401/12 , C07D403/12 , C07D405/12 , C07D409/04 , C07D413/12 , C07D417/12 , C07D471/04 , C07D491/10
摘要： Described herein are compounds that include a diarylamine structural feature. Also described herein are methods for making such compounds, methods for using such compounds to modulate the activity of c-kit receptors, and pharmaceutical compositions and medicaments comprising such compounds. Also described herein are methods of using such compounds, pharmaceutical compositions and medicaments to treat and/or prevent and/or inhibit and/or ameliorate the pathology and/or symptomology diseases or conditions associated with the activity of c-kit receptors.
摘要翻译： 本文描述的是包括二芳基胺结构特征的化合物。 本文还描述了制备这种化合物的方法，使用这些化合物调节c-kit受体的活性的方法，以及包含这些化合物的药物组合物和药物。 本文还描述了使用这些化合物，药物组合物和药物来治疗和/或预防和/或抑制和/或改善与c-kit受体活性相关的病理学和/或症状学疾病或病症的方法。
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公开(公告)号：US07402243B2
公开(公告)日：2008-07-22
申请号：US10938172
申请日：2004-09-10
IPC分类号： B01D15/08
CPC分类号： B01J20/288 , B01J20/286 , B01J20/287 , B01J20/289 , B01J20/3219 , B01J20/3242 , B01J20/3285 , C07F7/1804
摘要： The present invention provides novel silicon compounds, methods for making these novel silicon compounds, compositions comprising these novel silicon compounds attached to substrates, methods for attaching the novel silicon compounds to substrates and methods for using the compositions in a variety of chromatographic applications.
摘要翻译： 本发明提供新颖的硅化合物，制备这些新型硅化合物的方法，包含这些新型硅化合物附着在底物上的组合物，将新型硅化合物附着于底物的方法以及在各种色谱应用中使用该组合物的方法。
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公开(公告)号：US08425778B2
公开(公告)日：2013-04-23
申请号：US13464644
申请日：2012-05-04
IPC分类号： B01D15/08
CPC分类号： B01J20/288 , B01J20/286 , B01J20/287 , B01J20/289 , B01J20/3219 , B01J20/3242 , B01J20/3285 , C07F7/1804
摘要： The present invention provides novel silicon compounds, methods for making these novel silicon compounds, compositions comprising these novel silicon compounds attached to substrates, methods for attaching the novel silicon compounds to substrates and methods for using the compositions in a variety of chromatographic applications.
摘要翻译： 本发明提供了新颖的硅化合物，制备这些新型硅化合物的方法，包含这些新型硅化合物附着在底物上的组合物，将新型硅化合物附着于底物的方法以及在各种色谱应用中使用该组合物的方法。
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公开(公告)号：US20130026099A1
公开(公告)日：2013-01-31
申请号：US13464644
申请日：2012-05-04
CPC分类号： B01J20/288 , B01J20/286 , B01J20/287 , B01J20/289 , B01J20/3219 , B01J20/3242 , B01J20/3285 , C07F7/1804
摘要： The present invention provides novel silicon compounds, methods for making these novel silicon compounds, compositions comprising these novel silicon compounds attached to substrates, methods for attaching the novel silicon compounds to substrates and methods for using the compositions in a variety of chromatographic applications.
摘要翻译： 本发明提供了新颖的硅化合物，制备这些新型硅化合物的方法，包含这些新型硅化合物附着在底物上的组合物，将新型硅化合物附着于底物的方法以及在各种色谱应用中使用该组合物的方法。
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公开(公告)号：US20080203027A1
公开(公告)日：2008-08-28
申请号：US12111059
申请日：2008-04-28
CPC分类号： B01J20/288 , B01J20/286 , B01J20/287 , B01J20/289 , B01J20/3219 , B01J20/3242 , B01J20/3285 , C07F7/1804
摘要： The present invention, provides novel silicon compounds, methods for making these novel silicon compounds, compositions comprising these novel silicon compounds attached to substrates, methods for attaching the novel silicon compounds to substrates and methods for using the compositions in a variety of chromatographic applications.
摘要翻译： 本发明提供新的硅化合物，制备这些新型硅化合物的方法，包含这些新型硅化合物附着在基底上的组合物，将新型硅化合物附着于底物的方法以及在各种色谱应用中使用该组合物的方法。
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公开(公告)号：US20060054559A1
公开(公告)日：2006-03-16
申请号：US10938172
申请日：2004-09-10
IPC分类号： B01D15/08
CPC分类号： B01J20/288 , B01J20/286 , B01J20/287 , B01J20/289 , B01J20/3219 , B01J20/3242 , B01J20/3285 , C07F7/1804
摘要： The present invention provides novel silicon compounds, methods for making these novel silicon compounds, compositions comprising these novel silicon compounds attached to substrates, methods for attaching the novel silicon compounds to substrates and methods for using the compositions in a variety of chromatographic applications.
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