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公开(公告)号：US10647661B2
公开(公告)日：2020-05-12
申请号：US16032799
申请日：2018-07-11
发明人： Nadia Ahmad , Corey Anderson , Vijayalaksmi Arumugam , Iuliana Luci Asgian , Joanne Louise Camp , Lev Tyler Dewey Fanning , Sara Sabina Hadida Ruah , Dennis Hurley , Yvonne Schmidt , David Shaw , Urvi Patel , Stephen Andrew Thomson , Lidio Marx Carvalho Meireles
IPC分类号： C07D213/69 , C07D213/81 , C07D213/82 , C07D239/34 , C07D239/42 , C07D307/79 , C07D307/86 , C07D317/46 , C07D405/12 , C07C235/64 , A61K31/165 , C07C237/42 , C07D213/89
摘要： Compounds, and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharmaceutical compositions in the treatment of various disorders, including pain.
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公开(公告)号：US20230286961A1
公开(公告)日：2023-09-14
申请号：US17982983
申请日：2022-11-08
发明人： Steven John Durrant , Nadia M. Ahmad , Elizabeth Mary Beck , Lidio Marx Carvalho Meireles , Ewa Iwona Chudyk , Gorka Etxebarria Jardi , Bhairavi Galan , Sara S. Hadida Ruah , Dennis James Hurley , Ronald Marcellus Knegtel , Timothy Donald Neubert , Joanne Louise Pinder , Joseph Pontillo , Robert Pullin , Yvonne Schmidt , David Matthew Shaw , Sarah Skerratt , Dean Stamos , Stephen Andrew Thomson , Anisa Nizarali Virani , Christopher Wray
IPC分类号： C07D405/12 , C07D405/14 , C07D307/24
CPC分类号： C07D405/12 , C07D307/24 , C07D405/14 , C07B2200/13
摘要： Compounds, and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharmaceutical compositions in the treatment of various disorders, including pain.
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公开(公告)号：US11919887B2
公开(公告)日：2024-03-05
申请号：US17982983
申请日：2022-11-08
发明人： Steven John Durrant , Nadia M. Ahmad , Elizabeth Mary Beck , Lidio Marx Carvalho Meireles , Ewa Iwona Chudyk , Gorka Etxebarria Jardi , Bhairavi Galan , Sara S. Hadida Ruah , Dennis James Hurley , Ronald Marcellus Knegtel , Timothy Donald Neubert , Joanne Louise Pinder , Joseph Pontillo , Robert Pullin , Yvonne Schmidt , David Matthew Shaw , Sarah Skerratt , Dean Stamos , Stephen Andrew Thomson , Anisa Nizarali Virani , Christopher Wray
IPC分类号： C07D307/24 , C07D405/12 , C07D405/14
CPC分类号： C07D405/12 , C07D307/24 , C07D405/14 , C07B2200/13
摘要： Compounds, and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharmaceutical compositions in the treatment of various disorders, including pain.
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4.发明授权公开(公告)号：US11827627B2
公开(公告)日：2023-11-28
申请号：US17831842
申请日：2022-06-03
发明人： Elizabeth Mary Beck , Steven John Durrant , Sarah Skerratt , Robert Pullin , Gorka Etxebarria Jardi , David Matthew Shaw , Nadia M. Ahmad , Christopher Wray , Anisa Nizarali Virani , Kiri North , James Dodd , Michael Edward O'Donnell , Bhairavi Galan , Ronald Marcellus Knegtel , Ewa Iwona Chudyk , Joanne Louise Pinder , Stephen Andrew Thomson , Lidio Marx Carvalho Meireles , Dean Stamos , Yvonne Schmidt , Joseph Pontillo , Sara S. Hadida Ruah , Timothy Donald Neubert , Dennis James Hurley , Jinglan Zhou
IPC分类号： C07D405/12
CPC分类号： C07D405/12
摘要： Compounds, and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharmaceutical compositions in the treatment of various disorders, including pain.
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公开(公告)号：US11603351B2
公开(公告)日：2023-03-14
申请号：US16824255
申请日：2020-03-19
发明人： Nadia M. Ahmad , Corey Anderson , Vijayalaksmi Arumugam , Iuliana Luci Asgian , Joanne Louise Camp , Lev Tyler Dewey Fanning , Sara Sabina Hadida Ruah , Dennis Hurley , Yvonne Schmidt , David Shaw , Urvi Patel , Stephen Andrew Thomson , Lidio Marx Carvalho Meireles
IPC分类号： C07C235/64 , C07C237/42 , C07D307/86 , C07D239/42 , C07D213/69 , C07D213/82 , C07D213/89 , C07D239/34 , C07D307/79 , C07D317/46 , C07D405/12 , A61K31/165 , C07D213/81
摘要： Compounds, and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharmaceutical compositions in the treatment of various disorders, including pain.
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6.发明公开公开(公告)号：US20240182455A1
公开(公告)日：2024-06-06
申请号：US18491021
申请日：2023-10-20
发明人： Elizabeth Mary Beck , Steven John Durrant , Sarah Skerratt , Robert Pullin , Gorka Etxebarria Jardi , David Matthew Shaw , Nadia M. Ahmad , Christopher Wray , Anisa Nizarali Virani , Kiri North , James Dodd , Michael Edward O'Donnell , Bhairavi Galan , Ronald Marcellus Knegtel , Ewa Iwona Chudyk , Joanne Louise Pinder , Stephen Andrew Thomson , Lidio Marx Carvalho Meireles , Dean Stamos , Yvonne Schmidt , Joseph Pontillo , Sara S. Hadida Ruah , Timothy Donald Neubert , Dennis James Hurley , Jinglan Zhou
IPC分类号： C07D405/12
CPC分类号： C07D405/12
摘要： Compounds, and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharmaceutical compositions in the treatment of various disorders, including pain.
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公开(公告)号：US11834441B2
公开(公告)日：2023-12-05
申请号：US17112156
申请日：2020-12-04
发明人： Steven John Durrant , Nadia Ahmad , Elizabeth Mary Beck , Lidio Marx Carvalho Meireles , Ewa Iwona Chudyk , Gorka Etxebarria Jardi , Bhairavi Galan , Sara S. Hadida Ruah , Dennis James Hurley , Ronald Marcellus Knegtel , Timothy Donald Neubert , Joanne Louise Pinder , Joseph Pontillo , Robert Pullin , Yvonne Schmidt , David Matthew Shaw , Sarah Skerratt , Dean Stamos , Stephen Andrew Thomson , Anisa Nizarali Virani , Christopher Wray
IPC分类号： C07D405/12 , C07D307/24 , C07D405/14
CPC分类号： C07D405/12 , C07D307/24 , C07D405/14 , C07B2200/13
摘要： Compounds, and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharmaceutical compositions in the treatment of various disorders, including pain.
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公开(公告)号：US20210094906A1
公开(公告)日：2021-04-01
申请号：US16824255
申请日：2020-03-19
发明人： Nadia M. Ahmad , Corey Anderson , Vijayalaksmi Arumugam , Iuliana Luci Asgian , Joanne Louise Camp , Lev Tyler Dewey Fanning , Sara Sabina Hadida Ruah , Dennis Hurley , Yvonne Schmidt , David Shaw , Urvi Patel , Stephen Andrew Thomson , Lidio Marx Carvalho Meireles
IPC分类号： C07C235/64 , C07D239/42 , C07C237/42 , C07D307/86 , A61K31/165 , C07D405/12 , C07D317/46 , C07D307/79 , C07D239/34 , C07D213/89 , C07D213/82 , C07D213/81 , C07D213/69
摘要： Compounds, and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharmaceutical compositions in the treatment of various disorders, including pain.
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