公开(公告)号：US20150203503A1

公开(公告)日：2015-07-23

申请号：US14365064

申请日：2013-04-19

申请人： Vijaykumar Jagdishwar Patil ,  Ravikumar Tadiparthi ,  Bharat Dond ,  Amol Kale ,  Loganathan Velupillai ,  Deepak Dekhane ,  Satish Shrimant Birajdar ,  Mohammad Usman Shaikh ,  Sushilkumar Maurya ,  Piyush Ambalal Patel ,  Prasad Dixit ,  Mangesh Pawar ,  Mahesh Vithalbhai Patel ,  Sachin Bhagwat

发明人： Vijaykumar Jagdishwar Patil ,  Ravikumar Tadiparthi ,  Bharat Dond ,  Amol Kale ,  Loganathan Velupillai ,  Deepak Dekhane ,  Satish Shrimant Birajdar ,  Mohammad Usman Shaikh ,  Sushilkumar Maurya ,  Piyush Ambalal Patel ,  Prasad Dixit ,  Mangesh Pawar ,  Mahesh Vithalbhai Patel ,  Sachin Bhagwat

IPC分类号： C07D487/08 ,  A61K45/06 ,  A61K31/55 ,  A61K31/496 ,  A61K31/439 ,  A61K31/4545

CPC分类号： C07D471/08 ,  A61K31/407 ,  A61K31/439 ,  A61K31/4545 ,  A61K31/496 ,  A61K31/546 ,  A61K31/55 ,  A61K45/06 ,  A61P31/04 ,  C07C211/63 ,  C07D487/08

摘要： Compounds of Formula (I), their preparation and use in preventing or treating bacterial infections are disclosed.

摘要翻译： 公开了式（I）化合物及其制备和用于预防或治疗细菌感染的方法。

公开(公告)号：US20050192275A1

公开(公告)日：2005-09-01

申请号：US11082947

申请日：2005-03-18

申请人： Sudershan Arora ,  Vijaykumar Patil ,  Prathap Nair ,  Prasad Dixit ,  Shankar Ajay ,  Rakesh Sinha

发明人： Sudershan Arora ,  Vijaykumar Patil ,  Prathap Nair ,  Prasad Dixit ,  Shankar Ajay ,  Rakesh Sinha

IPC分类号： A61P31/00 ,  C07D263/20 ,  C07D413/10 ,  C07D413/14 ,  A61K31/541 ,  A61K31/422 ,  A61K31/496 ,  A61K31/5377 ,  C07D413/02 ,  C07D417/02

CPC分类号： C07D263/20 ,  C07D413/10 ,  C07D413/14

摘要： Novel compounds belonging to the class of oxazolidinones possessing potent antimycobacterial properties especially useful in the treatment of acid fast organisms such as Mycobacterium tuberculosis, Mycobacterium avium-intracellular complex, M. fortuitum and M. kansai. The compound and its pharmaceutically acceptable salts thereof act as antibacterial agents. Also disclosed is a method for inhibiting growth of mycobacterial cells as well as a method of treating mycobacterial conditions such as Mycobacterium tuberculosis, drug resistant Mycobacterium tuberculosis, Mycobacterium avium-intracellular complex, M. fortuitum and M. kansai, comprising administering an antimycobacterially effective amount of the said compound and/or pharmaceutically acceptable salts thereof. There is also disclosed a process for the manufacture of the said compound or its pharmaceutically acceptable salts.

摘要翻译： 属于恶唑烷酮类的新型化合物具有强效的抗分支杆菌特性，特别适用于治疗结核分枝杆菌，鸟分枝杆菌 - 细胞内复合物，偶然遗传和关西等酸性快速生物。 该化合物及其药学上可接受的盐作为抗菌剂。 还公开了一种抑制分枝杆菌细胞生长的方法以及治疗结核分枝杆菌，耐药性结核分枝杆菌，鸟分枝杆菌 - 细胞内复合物，偶发性偶联菌和关西氏菌等分枝杆菌病症的方法，其包括施用抗分枝杆菌有效量 的所述化合物和/或其药学上可接受的盐。 还公开了制备所述化合物或其药学上可接受的盐的方法。