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1.发明授权Amylases, nucleic acids encoding them and methods for making and using them 有权淀粉酶，编码它们的核酸和制备和使用它们的方法公开(公告)号：US07759093B2
公开(公告)日：2010-07-20
申请号：US10547957
申请日：2004-03-08
申请人： Walter Callen , Toby Richardson , Gerhard Frey , Kevin Gray , Janne S. Kerovuo , Malgorzata Slupska , Nelson Barton , Eileen O'Donoghue , Carl Miller
发明人： Walter Callen , Toby Richardson , Gerhard Frey , Kevin Gray , Janne S. Kerovuo , Malgorzata Slupska , Nelson Barton , Eileen O'Donoghue , Carl Miller
CPC分类号： A21D8/042 , A61K38/00 , C12C5/004 , C12N9/2411 , C12N9/2414 , C12N9/2428 , C12P19/14 , C12P19/16 , C12P19/20 , Y02E50/17
摘要： In one aspect, the invention is directed to polypeptides having an amylase activity, polynucleotides encoding the polypeptides, and methods for making and using these polynucleotides and polypeptides. In one aspect, the polypeptides of the invention can be used as amylases, for example, alpha amylases, to catalyze the hydrolysis of starch into sugars. In one aspect, the invention provides delayed release compositions comprising an desired ingredient coated by a latex polymer coating.
摘要翻译： 一方面，本发明涉及具有淀粉酶活性的多肽，编码多肽的多核苷酸，以及制备和使用这些多核苷酸和多肽的方法。 在一个方面，本发明的多肽可用作淀粉酶，例如α-淀粉酶，以催化淀粉水解成糖。 一方面，本发明提供包含通过胶乳聚合物涂层涂覆的所需成分的延迟释放组合物。
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2.发明授权Amylases, nucleic acids encoding them and methods for making and using them 有权淀粉酶，编码它们的核酸和制备和使用它们的方法公开(公告)号：US08222035B2
公开(公告)日：2012-07-17
申请号：US12822413
申请日：2010-06-24
申请人： Walter Callen , Toby Richardson , Gerhard Frey , Kevin A. Gray , Janne S. Kerovuo , Malgorzata Slupska , Nelson R. Barton , Eileen O'Donoghue , Carl Miller
发明人： Walter Callen , Toby Richardson , Gerhard Frey , Kevin A. Gray , Janne S. Kerovuo , Malgorzata Slupska , Nelson R. Barton , Eileen O'Donoghue , Carl Miller
CPC分类号： A21D8/042 , A61K38/00 , C12C5/004 , C12N9/2411 , C12N9/2414 , C12N9/2428 , C12P19/14 , C12P19/16 , C12P19/20 , Y02E50/17
摘要： In one aspect, the invention is directed to polypeptides having an amylase activity, polynucleotides encoding the polypeptides, and methods for making and using these polynucleotides and polypeptides. In one aspect, the polypeptides of the invention can be used as amylases, for example, alpha amylases, to catalyze the hydrolysis of starch into sugars. In one aspect, the invention provides delayed release compositions comprising an desired ingredient coated by a latex polymer coating.
摘要翻译： 一方面，本发明涉及具有淀粉酶活性的多肽，编码多肽的多核苷酸，以及制备和使用这些多核苷酸和多肽的方法。 在一个方面，本发明的多肽可用作淀粉酶，例如α-淀粉酶，以催化淀粉水解成糖。 一方面，本发明提供包含通过胶乳聚合物涂层涂覆的所需成分的延迟释放组合物。
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3.发明申请Amylases, nucleic acids encoding them and methods for making and using them 有权淀粉酶，编码它们的核酸和制备和使用它们的方法公开(公告)号：US20070157329A1
公开(公告)日：2007-07-05
申请号：US10547957
申请日：2004-03-08
申请人： Walter Callen , Toby Richardson , Gerhard Frey , Kevin Gray , Janne Kerovuo , Malgorzata Slupska , Nelson Barton , Eileen O'Donoghue , Carl Miller
发明人： Walter Callen , Toby Richardson , Gerhard Frey , Kevin Gray , Janne Kerovuo , Malgorzata Slupska , Nelson Barton , Eileen O'Donoghue , Carl Miller
IPC分类号： A01K67/027 , C12Q1/68 , C07H21/04 , C12P21/06 , A61K38/47 , C12P19/02 , C12N9/32 , A21D8/02 , C12C11/00 , C12P7/06 , C12N15/82 , C12N5/06
CPC分类号： A21D8/042 , A61K38/00 , C12C5/004 , C12N9/2411 , C12N9/2414 , C12N9/2428 , C12P19/14 , C12P19/16 , C12P19/20 , Y02E50/17
摘要： In one aspect, the invention is directed to polypeptides having an amylase activity, polynucleotides encoding the polypeptides, and methods for malting and using these polynucleotides and polypeptides. In one aspect, the polypeptides of the invention can be used as amylases, for example, alpha amylases, to catalyze the hydrolysis of starch into sugars. In one aspect, the invention provides delayed release compositions comprising an desired ingredient coated by a latex polymer coating.
摘要翻译： 一方面，本发明涉及具有淀粉酶活性的多肽，编码多肽的多核苷酸，以及用于发芽和使用这些多核苷酸和多肽的方法。 在一个方面，本发明的多肽可用作淀粉酶，例如α-淀粉酶，以催化淀粉水解成糖。 一方面，本发明提供包含通过胶乳聚合物涂层涂覆的所需成分的延迟释放组合物。
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4.发明授权Amylases, nucleic acids encoding them and methods for making and using them 有权淀粉酶，编码它们的核酸和制备和使用它们的方法公开(公告)号：US07560126B2
公开(公告)日：2009-07-14
申请号：US10385305
申请日：2003-03-06
申请人： Walter Callen , Toby Richardson , Gerhard Frey , Kevin A. Gray , Janne S. Kerovuo , Malgorzata Slupska , Nelson R. Barton , Eileen O'Donoghue , Eric J. Mathur , Jay M. Short
发明人： Walter Callen , Toby Richardson , Gerhard Frey , Kevin A. Gray , Janne S. Kerovuo , Malgorzata Slupska , Nelson R. Barton , Eileen O'Donoghue , Eric J. Mathur , Jay M. Short
CPC分类号： C12N9/2451 , A21D8/042 , A23K10/14 , A23K20/189 , A23L29/06 , A23L29/35 , C11D3/386 , C12C5/004 , C12N9/2417 , C12Y302/01001 , C12Y302/01002
摘要： In one aspect, the invention is directed to polypeptides having an amylase activity, polynucleotides encoding the polypeptides, and methods for making and using these polynucleotides and polypeptides. In one aspect, the polypeptides of the invention can be used as amylases, for example, alpha amylases, to catalyze the hydrolysis of starch into sugars.
摘要翻译： 一方面，本发明涉及具有淀粉酶活性的多肽，编码多肽的多核苷酸，以及制备和使用这些多核苷酸和多肽的方法。 在一个方面，本发明的多肽可用作淀粉酶，例如α-淀粉酶，以催化淀粉水解成糖。
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5.发明授权Enzymes having alpha amylase activity and methods of making and using them 有权具有α-淀粉酶活性的酶和制备和使用它们的方法公开(公告)号：US08334118B2
公开(公告)日：2012-12-18
申请号：US12567550
申请日：2009-09-25
申请人： Walter Callen , Toby Richardson , Gerhard Frey , Jay M. Short , Eric J. Mathur , Kevin A. Gray , Janne S. Kerovuo , Malgorzata Slupska
发明人： Walter Callen , Toby Richardson , Gerhard Frey , Jay M. Short , Eric J. Mathur , Kevin A. Gray , Janne S. Kerovuo , Malgorzata Slupska
CPC分类号： C12N9/2417 , A21D8/042 , C12N9/2414 , C12P19/04 , C12P19/14 , C12Y302/01001 , Y02E50/16 , Y02E50/17
摘要： The invention relates to alpha amylases and to polynucleotides and polypeptides encoding the alpha amylases. In addition, methods of using the alpha amylases are also provided. The alpha amylases have increased activity and stability at acidic, neutral and alkaline pH and at increased temperatures.
摘要翻译： 本发明涉及α-淀粉酶和编码α-淀粉酶的多核苷酸和多肽。 此外，还提供了使用α-淀粉酶的方法。 在酸性，中性和碱性pH和升高的温度下，α-淀粉酶具有增加的活性和稳定性。
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6.发明申请Enzymes Having Alpha Amylase Activity and Methods of Making and Using Them 有权具有α-淀粉酶活性的酶和制备和使用它们的方法公开(公告)号：US20100047392A1
公开(公告)日：2010-02-25
申请号：US12567550
申请日：2009-09-25
申请人： Walter Callen , Toby Richardson , Gerhard Frey , Jay M. Short , Eric J. Mathur , Kevin A. Gray , Janne S. Kerovuo , Malgorzata Slupska
发明人： Walter Callen , Toby Richardson , Gerhard Frey , Jay M. Short , Eric J. Mathur , Kevin A. Gray , Janne S. Kerovuo , Malgorzata Slupska
CPC分类号： C12N9/2417 , A21D8/042 , C12N9/2414 , C12P19/04 , C12P19/14 , C12Y302/01001 , Y02E50/16 , Y02E50/17
摘要： The invention relates to alpha amylases and to polynucleotides and polypeptides encoding the alpha amylases. In addition, methods of using the alpha amylases are also provided. The alpha amylases have increased activity and stability at acidic, neutral and alkaline pH and at increased temperatures.
摘要翻译： 本发明涉及α-淀粉酶和编码α-淀粉酶的多核苷酸和多肽。 此外，还提供了使用α-淀粉酶的方法。 在酸性，中性和碱性pH和升高的温度下，α-淀粉酶具有增加的活性和稳定性。
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7.发明授权Methods for using polypeptides having amylase activity and nucleic acids encoding them 有权使用具有淀粉酶活性的多肽和编码它们的核酸的方法公开(公告)号：US07816108B2
公开(公告)日：2010-10-19
申请号：US11621543
申请日：2007-01-09
申请人： Walter Callen , Toby Richardson , Gerhard Frey , Jay M. Short , Eric J. Mathur , Kevin A. Gray , Janne S. Kerovuo , Malgorzata Slupska
发明人： Walter Callen , Toby Richardson , Gerhard Frey , Jay M. Short , Eric J. Mathur , Kevin A. Gray , Janne S. Kerovuo , Malgorzata Slupska
CPC分类号： C12N9/2417 , A21D8/042 , C12N9/2414 , C12P19/04 , C12P19/14 , C12Y302/01001 , Y02E50/16 , Y02E50/17
摘要： The invention relates to uses of polypeptides having amylase activity, nucleic acids encoding them, and methods for making and using them. For example, in one aspect, the invention provides methods for making alcohol using polypeptides of the invention. In one aspect, the polypeptides having amylase activity have increased activity and stability at acidic, neutral and alkaline pH and increased temperature. In one aspect, the invention provides methods for producing an alcohol, for producing a high-maltose or a high-glucose syrup or a mixed syrup, for liquifying a starch-comprising composition, for hydrolyzing a starch, comprising use of polypeptides of the invention, or polypeptides encoded by the nucleic acids of this invention.
摘要翻译： 本发明涉及具有淀粉酶活性的多肽的用途，编码它们的核酸以及制备和使用它们的方法。 例如，一方面，本发明提供了使用本发明多肽制备醇的方法。 一方面，具有淀粉酶活性的多肽在酸性，中性和碱性pH和升高的温度下具有增加的活性和稳定性。 一方面，本发明提供用于生产高麦芽糖或高葡萄糖浆或混合糖浆的醇的方法，用于液化包含淀粉的组合物，用于水解淀粉，包括使用本发明的多肽 ，或由本发明的核酸编码的多肽。
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8.发明授权Nucleic acids encoding polypeptides having amylase activity and methods of making and using them 有权编码具有淀粉酶活性的多肽的核酸及其制备和使用方法公开(公告)号：US07785855B2
公开(公告)日：2010-08-31
申请号：US11621528
申请日：2007-01-09
申请人： Walter Callen , Toby Richardson , Gerhard Frey , Jay M. Short , Eric J. Mathur , Kevin A. Gray , Janne S. Kerovuo , Malgorzata Slupska
发明人： Walter Callen , Toby Richardson , Gerhard Frey , Jay M. Short , Eric J. Mathur , Kevin A. Gray , Janne S. Kerovuo , Malgorzata Slupska
CPC分类号： C12N9/2417 , A21D8/042 , C12N9/2414 , C12P19/04 , C12P19/14 , C12Y302/01001 , Y02E50/16 , Y02E50/17
摘要： The invention relates to nucleic acids encoding polypeptides having amylase activity, and methods for making and using them. In one aspect, the polypeptides having amylase activity have increased activity and stability at acidic, neutral and alkaline pH and increased temperature. In one aspect, the invention provides methods for producing an alcohol, for producing a high-maltose or a high-glucose syrup or a mixed syrup, for liquifying a starch-comprising composition, comprising use of polypeptides encoded by the nucleic acids of this invention.
摘要翻译： 本发明涉及编码具有淀粉酶活性的多肽的核酸，以及制备和使用它们的方法。 一方面，具有淀粉酶活性的多肽在酸性，中性和碱性pH和升高的温度下具有增加的活性和稳定性。 一方面，本发明提供用于生产用于液化含淀粉组合物的高麦芽糖或高葡萄糖浆或混合糖浆的醇的方法，其包括使用由本发明的核酸编码的多肽 。
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9.发明授权公开(公告)号：US07781201B2
公开(公告)日：2010-08-24
申请号：US11621534
申请日：2007-01-09
申请人： Walter Callen , Toby Richardson , Gerhard Frey , Jay M. Short , Eric J. Mathur , Kevin A. Gray , Janne S. Kerovuo , Malgorzata Slupska
发明人： Walter Callen , Toby Richardson , Gerhard Frey , Jay M. Short , Eric J. Mathur , Kevin A. Gray , Janne S. Kerovuo , Malgorzata Slupska
CPC分类号： C12N9/2417 , A21D8/042 , C12N9/2414 , C12P19/04 , C12P19/14 , C12Y302/01001 , Y02E50/16 , Y02E50/17
摘要： This invention relates generally to polypeptides and peptides having an amylase activity, e.g., enzymes, polynucleotides encoding the enzymes, the use of such polypeptides and peptides. In one aspect, the polypeptides having amylase activity have increased activity and stability at acidic, neutral and alkaline pH and increased temperature. In one aspect, the invention provides methods for producing an alcohol, for producing a high-maltose or a high-glucose syrup or a mixed syrup, for liquifying a starch-comprising composition, comprising use of polypeptides having amylase activity of the invention.
摘要翻译： 本发明一般涉及具有淀粉酶活性的多肽和肽，例如酶，编码酶的多核苷酸，这种多肽和肽的用途。 一方面，具有淀粉酶活性的多肽在酸性，中性和碱性pH和升高的温度下具有增加的活性和稳定性。 一方面，本发明提供了用于生产用于液化包含淀粉的组合物的高麦芽糖或高葡萄糖浆或混合糖浆的醇的方法，其包括使用具有本发明的具有淀粉酶活性的多肽。
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公开(公告)号：US07407677B2
公开(公告)日：2008-08-05
申请号：US10081872
申请日：2002-02-21
申请人： Walter Callen , Toby Richardson , Gerhard Frey , Jay M. Short , Eric J. Mathur , Kevin A. Gray , Janne S. Kerovuo , Malgorzata Slupska
发明人： Walter Callen , Toby Richardson , Gerhard Frey , Jay M. Short , Eric J. Mathur , Kevin A. Gray , Janne S. Kerovuo , Malgorzata Slupska
CPC分类号： C12N9/2417 , A21D8/042 , C12N9/2414 , C12P19/04 , C12P19/14 , C12Y302/01001 , Y02E50/16 , Y02E50/17
摘要： The invention relates to alpha amylases and to polynucleotides encoding the alpha amylases. In addition methods of designing new alpha amylases and methods of use thereof are also provided. The alpha amylases have increased activity and stability at acidic, neutral and alkaline pH and increased temperature.
摘要翻译： 本发明涉及α-淀粉酶和编码α-淀粉酶的多核苷酸。 另外还提供了设计新的α-淀粉酶的方法及其使用方法。 在酸性，中性和碱性pH和升高的温度下，α-淀粉酶具有增加的活性和稳定性。
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