公开(公告)号：US20050238583A1

公开(公告)日：2005-10-27

申请号：US11072951

申请日：2005-03-03

申请人： Walter Marzendorfer ,  Bernd Ohnesorge ,  Stefan Schaller

发明人： Walter Marzendorfer ,  Bernd Ohnesorge ,  Stefan Schaller

IPC分类号： A61K49/04

CPC分类号： A61K49/0409

摘要： A contrast agent for medical imaging has a component in the form of a chemical compound of gadolinium that is effective for x-ray computed tomography, that has at least one additive that prevents use of the contrast agent in magnetic resonance tomography.

摘要翻译： 用于医学成像的造影剂具有对于x射线计算机断层摄影有效的钆化学化合物形式的成分，其具有防止在磁共振断层摄影中使用造影剂的至少一种添加剂。

公开(公告)号：US07822467B2

公开(公告)日：2010-10-26

申请号：US10984834

申请日：2004-11-10

申请人： Thomas Flohr ,  Bernd Ohnesorge ,  Stefan Schaller

发明人： Thomas Flohr ,  Bernd Ohnesorge ,  Stefan Schaller

IPC分类号： A61B5/05

CPC分类号： A61B6/541 ,  A61B6/027 ,  A61B6/032 ,  A61B6/503 ,  A61B6/504

摘要： A method is for producing CT images of at least one second organ cyclically excited to move by a first organ moving on its own, or examination area with rest phases and activity phases of a patient. The second organ or the examination area is scanned, preferably spirally. A three-dimensional image of the absorption coefficient is determined with the aid of a multiplicity of cutting planes on the basis of the data obtained by scanning in the rest phase of the second organ or examination area, and the movement information required to determine the rest phase is collected from the first organ.

摘要翻译： 一种用于产生至少一个第二器官的CT图像的方法，所述至少一个第二器官通过自身移动的第一器官或患者的休息期和活动期的检查区域周期性地激发移动。 扫描第二个器官或检查区域，最好是螺旋状扫描。 基于通过在第二器官或检查区域的休息阶段扫描获得的数据和确定休息所需的移动信息，借助于多个切割平面来确定吸收系数的三维图像 阶段是从第一个器官收集的。

公开(公告)号：US07570983B2

公开(公告)日：2009-08-04

申请号：US10693586

申请日：2003-10-24

申请人： Christoph Becker ,  Roman Fischbach ,  Thomas Flohr ,  Andreas Kopp ,  Bernd Ohnesorge ,  Stefan Schaller

发明人： Christoph Becker ,  Roman Fischbach ,  Thomas Flohr ,  Andreas Kopp ,  Bernd Ohnesorge ,  Stefan Schaller

IPC分类号： A61B5/00

CPC分类号： A61B5/02007 ,  A61B5/7285 ,  A61B6/00 ,  A61B6/032 ,  A61B6/4085 ,  A61B6/481 ,  A61B6/504 ,  A61B6/541 ,  A61B8/543

摘要： In a method to support the diagnosis and/or therapy of a pathological change of a blood vessel of a patient, in particular in the context of coronary heart disease at a first point in time of a pixel-based or voxel-based first image is acquired with the blood vessel of interest by an imaging method, a determination is made from the first image of a quantity of existing non-calcified plaque and a quantity of existing calcium-rich plaque, a determination of a first indicator value is made from the quantities of the different plaque types that represents a measurement of the quantity and the composition of plaque present in the blood vessel at the first point in time, a comparison of the first indicator value is made with at least one limit value stored in a storage of a data processing device, and dependent on the comparison, a presentation is made on an output unit associated with the electronic data processing device of either a proposal for a measure to be undertaken on the patient, or a proposal for no measure.

摘要翻译： 在基于像素或基于体素的第一图像的第一时间点的支持诊断和/或治疗患者的血管的特别是在冠心病的情况下的诊断和/或治疗的方法是 通过成像方法用感兴趣的血管获取，从现有的非钙化斑块的量的第一图像和现有的富含钙的斑块的量确定第一指示剂值的确定是从 表示在第一时间点存在于血管中的斑块的量和组成的测量的不同斑块类型的量，第一指示剂值的比较与存储在存储器中的至少一个限制值进行比较 数据处理装置，并且根据比较，在与电子数据处理装置相关联的输出单元上呈现关于在患者上进行的措施的提案，o 一个不采取措施的提案。

公开(公告)号：US06665370B2

公开(公告)日：2003-12-16

申请号：US10191628

申请日：2002-07-09

申请人： Herbert Bruder ,  Thomas Flohr ,  Robert Mayer ,  Bernd Ohnesorge ,  Stefan Schaller ,  Karl Stierstorfer

发明人： Herbert Bruder ,  Thomas Flohr ,  Robert Mayer ,  Bernd Ohnesorge ,  Stefan Schaller ,  Karl Stierstorfer

IPC分类号： A61B603

CPC分类号： A61B6/032 ,  A61B6/027 ,  A61B6/4447 ,  A61B6/503 ,  G01N23/046 ,  G01N2223/419 ,  G01N2223/612

摘要： In a spiral scan cone beam computed tomography method and apparatus, the output data are divided into sub-segments being shorter than the length required for the reconstruction of a CT image. Segment images having inclined image plane relative to the system axis are reconstructed for the sub-segments. A signal reproducing the time curve of the periodic motion is acquired during the scanning. A z-position on the system axis and a time position with respect to the periodic motion are allocated to the segment images. Segment images belonging to a desired range of z-positions and a desired range of time positions are selected such that the corresponding sub-segments have an overall length adequate for the reconstruction of a CT image. The selected segment images are at least indirectly combined into a resulting CT image with respect to a target image plane.

摘要翻译： 在螺旋扫描锥束计算机断层摄影方法和装置中，输出数据被划分成比CT图像的重建所需的长度短的子段。 对于子段重建具有相对于系统轴的倾斜图像平面的段图像。 在扫描期间获取再现周期性运动的时间曲线的信号。 系统轴上的z位置和相对于周期运动的时间位置被分配给段图像。 选择属于期望的Z位置范围和期望的时间位置范围的段图像，使得对应的子段具有足以用于重建CT图像的总长度。 所选择的段图像至少间接地组合成相对于目标图像平面的结果CT图像。

公开(公告)号：US20050101858A1

公开(公告)日：2005-05-12

申请号：US10984834

申请日：2004-11-10

申请人： Thomas Flohr ,  Bernd Ohnesorge ,  Stefan Schaller

发明人： Thomas Flohr ,  Bernd Ohnesorge ,  Stefan Schaller

IPC分类号： A61B6/00 ,  A61B6/03 ,  A61B5/05

CPC分类号： A61B6/541 ,  A61B6/027 ,  A61B6/032 ,  A61B6/503 ,  A61B6/504

摘要： A method is for producing CT images of at least one second organ cyclically excited to move by a first organ moving on its own, or examination area with rest phases and activity phases of a patient. The second organ or the examination area is scanned, preferably spirally. A three-dimensional image of the absorption coefficient is determined with the aid of a multiplicity of cutting planes on the basis of the data obtained by scanning in the rest phase of the second organ or examination area, and the movement information required to determine the rest phase is collected from the first organ.

摘要翻译： 一种用于产生至少一个第二器官的CT图像的方法，所述至少一个第二器官通过自身移动的第一器官或患者的休息期和活动期的检查区域周期性地激发移动。 扫描第二个器官或检查区域，最好是螺旋状扫描。 基于通过在第二器官或检查区域的休息阶段扫描获得的数据和确定休息所需的移动信息，借助于多个切割平面来确定吸收系数的三维图像 阶段是从第一个器官收集的。

公开(公告)号：US06819736B1

公开(公告)日：2004-11-16

申请号：US10371702

申请日：2003-02-20

申请人： Herbert Bruder ,  Bernd Ohnesorge ,  Karl Stierstorfer ,  Thomas Flohr ,  Stefan Schaller

发明人： Herbert Bruder ,  Bernd Ohnesorge ,  Karl Stierstorfer ,  Thomas Flohr ,  Stefan Schaller

IPC分类号： A61B603

CPC分类号： A61B6/4028 ,  A61B6/027 ,  A61B6/032 ,  A61B6/4233 ,  A61B6/503 ,  G06T11/006 ,  G06T2211/412 ,  Y10S378/901

摘要： The invention relates to a method for performing computer tomography, and to a computed tomography (CT) apparatus, in which a) for scanning an object by a cone-shaped beam exiting from a focal point and by a matrix-like detector array for detecting the beam, the focal point is moved in relation to the object on a spiral path, whose center axis corresponds to a system axis, and the detector array provides output data corresponding to the received radiation; and b) for imaging an object region that executes a periodic motion, a signal that reproduces the course over time of the periodic motion is obtained during the scanning; c) from output data furnished during the motion of the focal point on a spiral segment, images with an inclined image plane are reconstructed, the image planes being inclined relative to the system axis both about a first axis, which perpendicularly intersects the system axis, by an angle of inclination &ggr; and about a second axis, which perpendicularly intersects both the first axis and the system axis, by a tilt angle &dgr;; and spiral segments that immediately succeed one another overlap one another by an overlap angle that is greater than or equal to zero; and the spiral segments are selected, taking into account the signal that reproduces the course over time of the periodic motion, such that they correspond to a phase of the periodic motion that is to be imaged.

摘要翻译： 本发明涉及一种用于执行计算机断层摄影的方法，以及计算机断层摄影（CT）装置，其中a）通过从焦点出射的锥形束和用于检测的矩阵状检测器阵列扫描物体 光束，焦点相对于螺旋路径上的物体移动，螺旋路径的中心轴对应于系统轴，并且检测器阵列提供对应于接收到的辐射的输出数据; 以及b）为了对执行周期性运动的对象区域进行成像，在扫描期间获得在周期性运动中再现该过程的信号; c）从在焦点的运动中在螺旋段上提供的输出数据中重建具有倾斜图像平面的图像，图像平面相对于垂直于系统轴线的第一轴线相对于系统轴线倾斜， 通过与第一轴和系统轴两者垂直相交的倾斜角γ和大约第二轴的倾斜角δ; 并且立即成功的螺旋段彼此重叠大于或等于零的重叠角; 并且考虑到再现周期性运动的时间过程的信号，使得它们对应于要成像的周期性运动的相位，并选择螺旋段。

公开(公告)号：US06556697B1

公开(公告)日：2003-04-29

申请号：US09396337

申请日：1999-09-15

申请人： Herbert Bruder ,  Thomas Flohr ,  Bernd Ohnesorge ,  Stefan Schaller ,  Bernhard Scholz

发明人： Herbert Bruder ,  Thomas Flohr ,  Bernd Ohnesorge ,  Stefan Schaller ,  Bernhard Scholz

IPC分类号： G06K900

CPC分类号： A61B6/541 ,  A61B5/0456 ,  A61B6/027 ,  A61B6/032 ,  A61B6/4085

摘要： In an image reconstruction method for imaging a periodically moving object with a computed tomography apparatus employing a multi-line detector unit, suitable selection of the rotational speed of the carrier of the computed tomography apparatus and employment of a three-dimensional back-projection algorithm, allow qualitatively high-great images of the object to be produced in every motion phase.

摘要翻译： 在利用采用多线检测器单元的计算机断层摄影装置对周期性运动物体进行成像的图像重建方法中，对计算机断层摄影装置的载体的旋转速度进行合适的选择并使用三维反投影算法， 允许在每个运动阶段产生对象的定性高伟大图像。

公开(公告)号：US5666391A

公开(公告)日：1997-09-09

申请号：US669931

申请日：1996-06-25

申请人： Bernd Ohnesorge ,  Ernstpeter Ruehrnschopf ,  Klaus Klingenbeck-Regn

发明人： Bernd Ohnesorge ,  Ernstpeter Ruehrnschopf ,  Klaus Klingenbeck-Regn

IPC分类号： A61B6/03 ,  G01N23/04 ,  H05G1/60

CPC分类号： A61B6/5282 ,  G01N23/046 ,  G01N2223/419

摘要： An x-ray examination apparatus with a detector array having a number of detector elements includes a data correction computer in which the subject-scattered radiation can be numerically determined and corrected. The forward scatter intensity is determined by multiplication of the measured intensities, windowed with a window function, with the natural logarithm of the intensity normalized with the unattenuated primary intensity. The subject-scattered radiation can then be calculated and corrected through filtering of the forward scatter intensity with a convolution kernel and a suitable scaling.

摘要翻译： 具有检测器元件数量的检测器阵列的X射线检查装置包括数据校正计算机，其中可以数字地确定和校正被摄体散射的辐射。 前向散射强度通过用窗函数加窗的测量强度乘以与未衰减的初始强度归一化的强度的自然对数来确定。 然后可以通过使用卷积核和合适的缩放过滤前向散射强度来计算和校正主体散射辐射。

公开(公告)号：US06560309B1

公开(公告)日：2003-05-06

申请号：US09724055

申请日：2000-11-28

申请人： Christoph Becker ,  Thomas Flohr ,  Bernd Ohnesorge

发明人： Christoph Becker ,  Thomas Flohr ,  Bernd Ohnesorge

IPC分类号： G01N2300

CPC分类号： A61B6/541 ,  A61B6/027 ,  G03B42/02 ,  H05G1/34

摘要： In a method for examining a body region executing a periodic motion in an examination subject with a diagnostic apparatus having a radiation source for generating radiation penetrating the examination subject and a detector system for the radiation emanating from the radiation source, the intensity of the radiation emanating from the radiation source is modulated between a reference value and a reduced value compared to the reference value, substantially synchronously with the movement, so that the reference value is present during a phase of the periodic motion to be imaged with the diagnostic apparatus, and substantially only the data that were output by the detector system during the presence of the reference value of the radiation are utilized for the determination of the image.

摘要翻译： 在利用具有用于产生穿过检查对象的辐射源的辐射源的诊断装置和用于从辐射源发出的辐射的检测器系统来检查检查对象中执行周期性运动的身体区域的方法中，辐射发射的强度 与基准值相比，辐射源在与基准值相比基准值和减小的值之间进行调制，与移动基本上同步，使得参考值在与诊断装置成像的周期性运动的相位期间存在， 仅在辐射的参考值存在期间由检测器系统输出的数据被用于图像的确定。

公开(公告)号：US06381487B1

公开(公告)日：2002-04-30

申请号：US09451228

申请日：1999-11-29

申请人： Thomas Flohr ,  Bernd Ohnesorge

发明人： Thomas Flohr ,  Bernd Ohnesorge

IPC分类号： A61B505

CPC分类号： A61B6/541 ,  A61B6/032 ,  A61B6/4085 ,  G01N23/04

摘要： In a method and CT apparatus for producing CT images of a body region periodically moving with resting or motion phases, data corresponding to a number of projections serving the purpose of imaging are analyzed to determine whether each projection was acquired during a resting or motion phase, and only those data that were acquired during a resting phase are employed for image reconstruction.

摘要翻译： 在用于产生以休息或运动相位周期性移动的身体区域的CT图像的方法和CT装置中，分析与用于成像目的的多个投影对应的数据，以确定在休息或运动阶段期间是否获取每个投影， 并且仅将在静止阶段获取的数据用于图像重建。