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公开(公告)号:US08338180B2
公开(公告)日:2012-12-25
申请号:US10865663
申请日:2004-06-09
CPC分类号: C12Q1/702 , G01N33/5008 , G01N33/56983 , G01N2333/155 , G01N2500/00
摘要: The present invention provides methods of identifying an agent that inhibits an activity of a lentiviral Vif protein. The present invention provides methods of identifying an agent that increases the level of active APOBEC3G in a cell. The present invention provides agents identified by a subject screening method; and further provides methods for treating lentivirus infections.
摘要翻译: 本发明提供鉴定抑制慢病毒Vif蛋白活性的试剂的方法。 本发明提供鉴定增加细胞中活性APOBEC3G水平的试剂的方法。 本发明提供了通过受试者筛选方法鉴定的药剂; 并进一步提供治疗慢病毒感染的方法。
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公开(公告)号:US07723021B2
公开(公告)日:2010-05-25
申请号:US11671991
申请日:2007-02-06
申请人: Warner C. Greene , Kimberly S. Stopak , Carlos M. deNoronha , Ya-Lin Chiu , Vanessa B. Soros , Wesley M. Yonemoto
发明人: Warner C. Greene , Kimberly S. Stopak , Carlos M. deNoronha , Ya-Lin Chiu , Vanessa B. Soros , Wesley M. Yonemoto
IPC分类号: C12Q1/00
CPC分类号: C12Q1/702 , G01N33/5008 , G01N33/56983 , G01N2333/155 , G01N2500/00
摘要: The present invention provides methods of identifying an agent that inhibits an activity of a lentiviral Vif protein. The present invention provides methods of identifying an agent that increases the level of active APOBEC3G in a cell. The present invention provides agents identified by a subject screening method; and further provides methods for treating lentivirus infections.
摘要翻译: 本发明提供鉴定抑制慢病毒Vif蛋白活性的试剂的方法。 本发明提供鉴定增加细胞中活性APOBEC3G水平的试剂的方法。 本发明提供了通过受试者筛选方法鉴定的药剂; 并进一步提供治疗慢病毒感染的方法。
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