Stable, water-soluble quantum dot, method of preparation and conjugates thereof
    1.
    发明申请
    Stable, water-soluble quantum dot, method of preparation and conjugates thereof 有权
    稳定的水溶性量子点,其制备方法和共轭物

    公开(公告)号:US20060014315A1

    公开(公告)日:2006-01-19

    申请号:US11116454

    申请日:2005-04-28

    IPC分类号: H01L51/40

    摘要: A method for manufacturing powdered quantum dots comprising the steps of: a) reacting quantum dots comprising a core, a cap and a first ligand associated with the outer surfaces thereof with a second ligand, the second ligand displacing the first ligand and attaching to the outer surfaces of the quantum dots, b) isolating the quantum dots having the attached second ligand from the reaction mixture, c) reacting the isolated quantum dots having the attached second ligand with a small organic molecule whereby the small organic molecule attaches to the second ligand, d) reacting the quantum dots having the attached small organic molecule with a cross-linking agent to cross-link the small organic molecule attached to the second ligand with an adjacent second ligand attached to the surfaces of the quantum dots, e) isolating the quantum dots formed in step (d); and f) drying the isolated quantum dots to form powdered quantum dots. The invention includes the quantum dots.

    摘要翻译: 一种制造粉末状量子点的方法,包括以下步骤:a)使包含芯,帽和与其外表面相关联的第一配体的量子点与第二配体反应,第二配体置换第一配体并附着于外层 量子点的表面,b)从反应混合物中分离具有附着的第二配体的量子点,c)使具有附着的第二配体的分离量子点与小有机分子反应,由此小有机分子连接到第二配体, d)使具有连接的小有机分子的量子点与交联剂反应,以将连接到第二配体的小有机分子与附着于量子点表面的相邻第二配体交联,e)分离量子 在步骤(d)中形成的点; 和f)干燥分离的量子点以形成粉末状量子点。 本发明包括量子点。

    Stable, water-soluble quantum dot, method of preparation and conjugates thereof
    2.
    发明申请
    Stable, water-soluble quantum dot, method of preparation and conjugates thereof 审中-公开
    稳定的水溶性量子点,其制备方法和共轭物

    公开(公告)号:US20070042576A1

    公开(公告)日:2007-02-22

    申请号:US11589078

    申请日:2006-10-30

    IPC分类号: H01G9/20

    摘要: A method for manufacturing powdered quantum dots comprising the steps of: a) reacting quantum dots comprising a core, a cap and a first ligand associated with the outer surfaces thereof with a second ligand, the second ligand displacing the first ligand and attaching to the outer surfaces of the quantum dots, b) isolating the quantum dots having the attached second ligand from the reaction mixture, c) reacting the isolated quantum dots having the attached second ligand with a small organic molecule whereby the small organic molecule attaches to the second ligand, d) reacting the quantum dots having the attached small organic molecule with a cross-linking agent to cross-link the small organic molecule attached to the second ligand with an adjacent second ligand attached to the surfaces of the quantum dots, e) isolating the quantum dots formed in step (d); and f) drying the isolated quantum dots to form powdered quantum dots. The invention includes the quantum dots.

    摘要翻译: 一种制造粉末状量子点的方法,包括以下步骤:a)使包含芯,帽和与其外表面相关联的第一配体的量子点与第二配体反应,第二配体置换第一配体并附着到外层 量子点的表面,b)从反应混合物中分离具有附着的第二配体的量子点,c)使具有附着的第二配体的分离量子点与小有机分子反应,由此小有机分子连接到第二配体, d)使具有连接的小有机分子的量子点与交联剂反应,以将连接到第二配体的小有机分子与附着于量子点表面的相邻第二配体交联,e)分离量子 在步骤(d)中形成的点; 和f)干燥分离的量子点以形成粉末状量子点。 本发明包括量子点。

    Patterns for pre-formatted information on magnetic hard disk media
    4.
    发明授权
    Patterns for pre-formatted information on magnetic hard disk media 有权
    磁盘硬盘介质预格式化信息模式

    公开(公告)号:US07944643B1

    公开(公告)日:2011-05-17

    申请号:US11950570

    申请日:2007-12-05

    IPC分类号: G11B5/596

    CPC分类号: G11B5/59688

    摘要: A magnetic disk media is physically preformatted to have a non-user data area providing any of a servo pattern, a gray code pattern and a timing line pattern. The non-user data area patterns are preformatted to have non-recordable regions with a radial width that is always less than the track pitch of the data area. In exemplary implementations, servo patterns, gray code patterns and timing line patterns are physically preformatted to have a recordable:non-recordable radial width ratio substantially equal to that of a user data area. In certain embodiments, non-magnetic or magnetically suppressed regions having cross-track dimension substantially equal to that of spaces between tracks in the user data area are consecutively offset in a cross-track direction from the discrete track recording pattern of the user data area.

    摘要翻译: 物理地预先格式化磁盘介质以具有提供任何伺服图案,灰度码图案和定时线图案的非用户数据区域。 非用户数据区域模式被预格式化以具有总是小于数据区的轨道间距的径向宽度的不可记录区域。 在示例性实施方式中,伺服图案,灰度图案和定时线图案被物理地预格式化以具有基本上等于用户数据区域的可记录的:不可记录的径向宽度比。 在某些实施例中,具有与用户数据区域中的轨道之间的间隔基本相等的交叉轨道尺寸的非磁性或磁性抑制区域在与用户数据区域的离散轨道记录模式的交叉磁道方向上连续偏移。

    Composite soft underlayer including negative anisotropy material
    5.
    发明授权
    Composite soft underlayer including negative anisotropy material 有权
    复合软底层包括负向各向异性材料

    公开(公告)号:US08455118B2

    公开(公告)日:2013-06-04

    申请号:US12872865

    申请日:2010-08-31

    IPC分类号: G11B5/62 G11B5/667

    CPC分类号: G11B5/667

    摘要: An apparatus may include a composite soft underlayer and a perpendicular magnetic recording layer overlying the composite soft underlayer. The composite soft underlayer may include a growth template layer, a negative magnetic anisotropy layer overlying the growth template layer, and a magnetically soft layer overlying the negative magnetic anisotropy layer. In some embodiments, the negative magnetic anisotropy layer includes a plurality of grains, and substantially all the grains have negative magnetic anisotropy along an axis substantially perpendicular to a major plane of the composite soft underlayer. In some embodiments, the negative magnetic anisotropy layer includes a thickness of less than or equal to about 3 nm.

    摘要翻译: 装置可以包括复合软底层和覆盖复合软底层的垂直磁记录层。 复合软底层可以包括生长模板层,覆盖生长模板层的负磁各向异性层和覆盖负磁各向异性层的磁软层。 在一些实施例中,负磁各向异性层包括多个晶粒,并且基本上所有的晶粒沿着基本上垂直于复合软底层的主平面的轴线具有负的磁各向异性。 在一些实施例中,负磁各向异性层包括小于或等于约3nm的厚度。

    Association acceleration for transaction databases
    6.
    发明授权
    Association acceleration for transaction databases 有权
    交易数据库的关联加速

    公开(公告)号:US09110969B2

    公开(公告)日:2015-08-18

    申请号:US13746791

    申请日:2013-01-22

    IPC分类号: G06F17/00 G06F17/30

    CPC分类号: G06F17/30595 G06F17/30536

    摘要: An association rule accelerator may be used to access a transaction database storing a plurality of transactions, each transaction including one or more items. The association rule accelerator also may select a sampling rate based on an item frequency of frequent items within the transaction database, relative to a sampled item frequency of sampled items within a corresponding sampled transaction database. An an association rule selector may determine, using the selected sampling rate and corresponding sampled transaction database, frequent item sets within the sampled transactions, and may further determine an association rule relating at least two items of the sampled transactions, based on the frequent item sets.

    摘要翻译: 可以使用关联规则加速器来访问存储多个事务的事务数据库,每个事务包括一个或多个事务。 关联规则加速器还可以相对于对应的采样事务数据库内的采样项目的采样项目频率,选择基于事务数据库内的频繁项目的项目频率的采样率。 关联规则选择器可以使用所选择的采样率和相应的采样事务数据库来确定采样事务内的频繁项目集合,并且可以基于频繁项集合进一步确定与至少两个采样事务项目有关的关联规则 。

    COMPOSITE SOFT UNDERLAYER INCLUDING NEGATIVE ANISOTROPY MATERIAL
    7.
    发明申请
    COMPOSITE SOFT UNDERLAYER INCLUDING NEGATIVE ANISOTROPY MATERIAL 有权
    复合软底层,包括负面的各向异性材料

    公开(公告)号:US20120052327A1

    公开(公告)日:2012-03-01

    申请号:US12872865

    申请日:2010-08-31

    IPC分类号: G11B5/62

    CPC分类号: G11B5/667

    摘要: An apparatus may include a composite soft underlayer and a perpendicular magnetic recording layer overlying the composite soft underlayer. The composite soft underlayer may include a growth template layer, a negative magnetic anisotropy layer overlying the growth template layer, and a magnetically soft layer overlying the negative magnetic anisotropy layer. In some embodiments, the negative magnetic anisotropy layer includes a plurality of grains, and substantially all the grains have negative magnetic anisotropy along an axis substantially perpendicular to a major plane of the composite soft underlayer. In some embodiments, the negative magnetic anisotropy layer includes a thickness of less than or equal to about 3 nm

    摘要翻译: 装置可以包括复合软底层和覆盖复合软底层的垂直磁记录层。 复合软底层可以包括生长模板层,覆盖生长模板层的负磁各向异性层和覆盖负磁各向异性层的磁软层。 在一些实施例中,负磁各向异性层包括多个晶粒,并且基本上所有的晶粒沿着基本上垂直于复合软底层的主平面的轴线具有负的磁各向异性。 在一些实施例中,负磁各向异性层包括小于或等于约3nm的厚度

    Recombinant sequence, its preparation and use
    8.
    发明申请
    Recombinant sequence, its preparation and use 审中-公开
    重组序列,其制备及应用

    公开(公告)号:US20060104964A1

    公开(公告)日:2006-05-18

    申请号:US11328070

    申请日:2006-01-10

    申请人: Wen Jiang

    发明人: Wen Jiang

    CPC分类号: C07K14/475

    摘要: An isolated, purified or recombinant nucleic acid sequence is disclosed, comprising: (a) a sequence that encodes both an angiogenic factor antagonist and a vascular endothelial structure regulator; (b) a sequence substantially homologous to or that hybridises to sequence (a) under stringent conditions; or (c) a sequence substantially homologous to or that hybridises under stringent conditions to the sequence (a) or (b) but for the degeneracy of the genetic code; or (d) an oligonucleotide specific for any of the sequences (a), (b) or (c). Particular oligonucleotides (d) are those encoding the vascular endothelial structure regulator. Also described are methods for preparing the recombinant polynucleotide, proteins encoded by such polynucleotides and their use in gene or protein therapy for the treatment of conditions such as cancer.

    摘要翻译: 公开了分离的,纯化的或重组的核酸序列,其包含:(a)编码血管生成因子拮抗剂和血管内皮结构调节剂的序列; (b)在严格条件下与序列(a)基本同源或杂交的序列; 或(c)在严格条件下与序列(a)或(b)基本上同源或杂交的序列,但是遗传密码的简并性; 或(d)对(a),(b)或(c)中的任一种具有特异性的寡核苷酸。 具体的寡核苷酸(d)是编码血管内皮结构调节剂的寡核苷酸。 还描述了制备重组多核苷酸,由这些多核苷酸编码的蛋白质及其在基因或蛋白质治疗中用于治疗诸如癌症的病症的方法。

    Method of mitigating eccentricity in a disk drive with DTR media
    9.
    发明申请
    Method of mitigating eccentricity in a disk drive with DTR media 失效
    使用DTR介质减轻磁盘驱动器偏心率的方法

    公开(公告)号:US20060066994A1

    公开(公告)日:2006-03-30

    申请号:US10949459

    申请日:2004-09-24

    IPC分类号: G11B17/02

    CPC分类号: G11B19/2009 G11B25/043

    摘要: A disk drive with DTR media and method of assembly is described. The method may include aligning a discrete track recording (DTR) track pattern center on a DTR disk with a rotational center of a spindle hub and mounting the DTR disk on the spindle hub to minimize eccentricity. After the DTR disk is mounted to the spindle hub, it may be rotated to a designed rotational speed and the mass imbalance of the rotating DTR disk/spindle hub may be measured. The mass imbalance may be mitigated using a mechanical component such as a counter weight coupled to a spindle rotatable component, for example, the spindle hub, a spacer assembly, a clamp assembly, etc. The method may mitigate the eccentricity associated with DTR media and minimize run-out due to the mass imbalance of an otherwise rotated DTR disk/hub aligned for eccentricity correction.

    摘要翻译: 描述了具有DTR介质和组装方法的磁盘驱动器。 该方法可以包括将DTR盘上的离散轨迹记录(DTR)轨迹图形中心与主轴毂的旋转中心对准,并将DTR盘安装在主轴毂上以最小化偏心度。 在DTR盘安装到主轴毂之后,可以将其旋转到设计的转速,并且可以测量旋转DTR盘/主轴毂的质量不平衡。 质量不平衡可以使用诸如耦合到主轴可旋转部件(例如主轴毂,间隔件组件,夹具组件等)的机械部件的机械部件来减轻。该方法可以减轻与DTR介质相关联的偏心率, 尽可能减少由于对准用于偏心校正的另外旋转的DTR盘/毂的质量不平衡造成的跳动。

    Novel column packing material
    10.
    发明申请
    Novel column packing material 有权
    新型柱包装材料

    公开(公告)号:US20050064192A1

    公开(公告)日:2005-03-24

    申请号:US10710937

    申请日:2004-08-13

    申请人: Wen Jiang Knut Irgum

    发明人: Wen Jiang Knut Irgum

    摘要: A porous silica particle suitable can be used in zwitterionic high performance liquid chromatography. The particle comprises covalently bound zwitterionic groups grafted through a polymerization reaction. A hydrophilic column packing material suitable for use as a stationary phase in zwitterionic high performance liquid chromatography may comprise porous silica particles. The particles may comprise covalently bound zwitterionic groups. Methods for manufacturing and applying the silica particles exist.

    摘要翻译: 合适的多孔二氧化硅颗粒可用于两性离子高效液相色谱。 该颗粒包括通过聚合反应接枝的共价结合的两性离子基团。 适用于两性离子高效液相色谱法中的固定相的亲水柱填料可以包括多孔二氧化硅颗粒。 颗粒可以包含共价结合的两性离子基团。 存在制造和施加二氧化硅颗粒的方法。