公开(公告)号：US20180231461A1

公开(公告)日：2018-08-16

申请号：US15953276

申请日：2018-04-13

Applicant: Waters Technologies Corporation

Inventor： Anthony C. Jeannotte ,  Mark Basile ,  Senthil Bala ,  Colin Fredette

IPC: G01N21/41 ,  G01N21/05 ,  G01N30/74

CPC classification number: G01N21/4133 ,  G01N21/05 ,  G01N30/74 ,  G01N2021/4146

Abstract: The invention provides differential refractive index detectors and methods for the use of differential refractive index detectors. In an exemplary embodiment, a differential refractive index detector includes a flow cell body having a proximal end, a distal end, and a flow axis extending between the proximal and the distal end. The flow cell body includes a first chamber and a second chamber and the fluid conduits coupled to the flow cell body can be tapered to reduce dispersion.

公开(公告)号：US11268902B2

公开(公告)日：2022-03-08

申请号：US15953276

申请日：2018-04-13

Applicant: Waters Technologies Corporation

Inventor： Anthony C. Jeannotte ,  Mark Basile ,  Senthil Bala ,  Colin Fredette

IPC: G01N21/41 ,  G01N21/05 ,  G01N30/74

Abstract: The invention provides differential refractive index detectors and methods for the use of differential refractive index detectors. In an exemplary embodiment, a differential refractive index detector includes a flow cell body having a proximal end, a distal end, and a flow axis extending between the proximal and the distal end. The flow cell body includes a first chamber and a second chamber and the fluid conduits coupled to the flow cell body can be tapered to reduce dispersion.

公开(公告)号：US11604174B2

公开(公告)日：2023-03-14

申请号：US16684930

申请日：2019-11-15

Applicant: Waters Technologies Corporation

Inventor： Abhijit Tarafder ,  Sebastien Besner ,  Mark Basile ,  Martin Gilar

IPC: G01N30/74 ,  G01N21/33 ,  G01N30/32 ,  G01N30/34

Abstract: Exemplary embodiments are directed to methods and systems for controlling fluid parameters within a detector. A first and second fluid pump manager control the flow of a first and second fluid to one or more heating/cooling devices, and a mixer receives and mixes the first and second fluids. An optical detector flow cell receives the fluid mixture from the mixer, and a pressure regulator controls the pressure at the optical detector flow cell. Thus, the composition, temperature, and pressure of a fluid mixture entering an optical detector flow cell can be controlled in real time.

公开(公告)号：US20200158605A1

公开(公告)日：2020-05-21

申请号：US16684930

申请日：2019-11-15

Applicant: Waters Technologies Corporation

Inventor： Abhijit Tarafder ,  Sebastien Besner ,  Mark Basile ,  Martin Gilar

IPC: G01N1/38 ,  G01N21/01 ,  G01N21/33

Abstract: Exemplary embodiments are directed to methods and systems for controlling fluid parameters within a detector. A first and second fluid pump manager control the flow of a first and second fluid to one or more heating/cooling devices, and a mixer receives and mixes the first and second fluids. An optical detector flow cell receives the fluid mixture from the mixer, and a pressure regulator controls the pressure at the optical detector flow cell. Thus, the composition, temperature, and pressure of a fluid mixture entering an optical detector flow cell can be controlled in real time.

公开(公告)号：US09989459B2

公开(公告)日：2018-06-05

申请号：US14775752

申请日：2014-03-11

Applicant: Waters Technologies Corporation

Inventor： Anthony C. Jeannotte ,  Mark Basile ,  Senthil Bala ,  Colin Fredette

IPC: G01N21/05 ,  G01N30/74 ,  G01N21/41

CPC classification number: G01N21/4133 ,  G01N21/05 ,  G01N30/74 ,  G01N2021/4146

Abstract: The invention provides differential refractive index detectors and methods for the use of differential refractive index detectors. In an exemplary embodiment, a differential refractive index detector includes a flow cell body having a proximal end, a distal end, and a flow axis extending between the proximal and the distal end. The flow cell body includes a first chamber and a second chamber and the fluid conduits coupled to the flow cell body can be tapered to reduce dispersion.