公开(公告)号：US20070055352A1

公开(公告)日：2007-03-08

申请号：US11221647

申请日：2005-09-07

申请人： Wendy Naimark ,  Peter Shank ,  Maria Palasis ,  Toby Freyman ,  Anastasia Panos ,  Samuel Epstein ,  Alexandra Rousseau

发明人： Wendy Naimark ,  Peter Shank ,  Maria Palasis ,  Toby Freyman ,  Anastasia Panos ,  Samuel Epstein ,  Alexandra Rousseau

IPC分类号： A61F2/90

CPC分类号： A61L31/16 ,  A61F2/91 ,  A61F2/915 ,  A61F2002/075 ,  A61F2002/91525 ,  A61F2002/91533 ,  A61F2002/91575 ,  A61F2210/0076 ,  A61F2220/0008 ,  A61F2230/0013 ,  A61F2250/0068 ,  A61L2300/606

摘要： A medical device for: delivering a therapeutic agent to a body lumen is described. The device may generally be a stent with an inner sidewall surface and an outer sidewall surface, with a plurality of struts having a plurality of openings therein. An inner and outer layer may be applied to the stent, forming pockets within at least a portion of the openings. The pockets may be filled with at least one therapeutic agent. The pockets may take a variety of shapes and sizes, and may be designed for release or rupture in variety of ways.

摘要翻译： 描述了用于将治疗剂递送到体腔的医疗装置。 该装置通常可以是具有内侧壁表面和外侧壁表面的支架，多个支柱在其中具有多个开口。 内层和外层可以施加到支架上，在开口的至少一部分内形成袋。 口袋可以填充有至少一种治疗剂。 口袋可以采取各种形状和尺寸，并且可以设计为以各种方式释放或破裂。

公开(公告)号：US20080051702A1

公开(公告)日：2008-02-28

申请号：US11726608

申请日：2007-03-22

申请人： Robert A. Herrmann ,  John J. Damarati ,  Sepideh Hashemi ,  Wendy Naimark ,  Barry N. Gellman ,  Robert Rioux ,  Alexandra Rousseau ,  Raymond Lareau

发明人： Robert A. Herrmann ,  John J. Damarati ,  Sepideh Hashemi ,  Wendy Naimark ,  Barry N. Gellman ,  Robert Rioux ,  Alexandra Rousseau ,  Raymond Lareau

IPC分类号： A61K31/573

CPC分类号： A61K31/573

摘要： Methods for the treatment of asthma are provided, which comprise: (a) providing an implantable or insertable medical device that comprises an asthma treatment agent; and (b) inserting or implanting the medical device within the lungs (e.g., the trachea or the bronchial tree) of a patient, whereupon the therapeutic agent is delivered to the patient in an amount effective to reduce or eliminate the symptoms of asthma. Also disclosed herein are medical devices and kits for carrying out such methods.

摘要翻译： 提供了治疗哮喘的方法，其包括：（a）提供包含哮喘治疗剂的可植入或可插入的医疗装置; 和（b）将医疗装置插入或植入患者的肺部（例如，气管或支气管树）中，于是将治疗剂以有效减少或消除哮喘症状的量递送给患者。 本文还公开了用于执行这些方法的医疗装置和套件。

公开(公告)号：US20120231047A1

公开(公告)日：2012-09-13

申请号：US13480227

申请日：2012-05-24

申请人： Robert A. Herrmann ,  John J. Damarati ,  Sepideh Hashemi ,  Wendy Naimark ,  Barry N. Gellman ,  Robert Rioux ,  Alexandra Rousseau ,  Raymond Lareau

发明人： Robert A. Herrmann ,  John J. Damarati ,  Sepideh Hashemi ,  Wendy Naimark ,  Barry N. Gellman ,  Robert Rioux ,  Alexandra Rousseau ,  Raymond Lareau

IPC分类号： A61K31/56 ,  A61K47/02 ,  A61P11/06 ,  A61M37/00 ,  A61P35/00 ,  A61P21/02 ,  A61M25/10 ,  A61K9/00 ,  A61P29/00

CPC分类号： A61K31/573

摘要： Methods for the treatment of asthma are provided, which comprise: (a) providing an implantable or insertable medical device that comprises an asthma treatment agent; and (b) inserting or implanting the medical device within the lungs (e.g., the trachea or the bronchial tree) of a patient, whereupon the therapeutic agent is delivered to the patient in an amount effective to reduce or eliminate the symptoms of asthma. Also disclosed herein are medical devices and kits for carrying out such methods.

摘要翻译： 提供了治疗哮喘的方法，其包括：（a）提供包含哮喘治疗剂的可植入或可插入的医疗装置; 和（b）将医疗装置插入或植入患者的肺部（例如，气管或支气管树）中，于是将治疗剂以有效减少或消除哮喘症状的量递送给患者。 本文还公开了用于执行这些方法的医疗装置和套件。

公开(公告)号：US08728093B2

公开(公告)日：2014-05-20

申请号：US12209591

申请日：2008-09-12

申请人： Alexandra Rousseau ,  Mark Wood ,  Jon T. McIntyre ,  Claude Clerc ,  Gary Leanna ,  Michael S. H. Chu

发明人： Alexandra Rousseau ,  Mark Wood ,  Jon T. McIntyre ,  Claude Clerc ,  Gary Leanna ,  Michael S. H. Chu

IPC分类号： A61B17/10

CPC分类号： A61B17/12013 ,  A61B17/12009 ,  A61B2017/0419 ,  A61B2017/12018

摘要： A lung volume reduction system includes a percutaneously, laparoscopically or thorocospically insertable delivery element comprising a control end which remains outside the body and an insertion end which, when in an operative position, is adjacent to an external surface of a target portion of a lung and a constriction element deployable from the distal end of the delivery element to apply compressive force to an external surface of the target portion of the lung to constrict at least one airway therein and collapse the target portion of the lung.

摘要翻译： 肺容积减小系统包括经皮，腹腔镜或胸腔可插入的输送元件，其包括保持在身体外部的控制端和当处于操作位置时与肺的目标部分的外表面相邻的插入端，以及 收缩元件可从输送元件的远端展开，以向肺的目标部分的外表面施加压缩力，以收缩其中的至少一个气道并折叠肺的目标部分。

公开(公告)号：US08016749B2

公开(公告)日：2011-09-13

申请号：US11385320

申请日：2006-03-21

申请人： Claude O Clerc ,  John Hutchins ,  Alexandra Rousseau ,  F Anthony Headley, Jr.

发明人： Claude O Clerc ,  John Hutchins ,  Alexandra Rousseau ,  F Anthony Headley, Jr.

IPC分类号： A61B1/00 ,  A61B1/012

CPC分类号： A61B1/018 ,  A61B1/2676 ,  A61B5/065

摘要： Embodiments of the present invention are generally directed to a visualization system including a small gauge vision catheter that is designed to be standalone or received within an instrument channel of a larger endoscope. The vision catheter has imaging means disposable within an imaging channel, a working channel, and an electromagnetic sensor element insertable into the working channel of the catheter to provide position tracking. The working channel of the catheter also provides access for therapeutic and diagnostic tools.

摘要翻译： 本发明的实施例一般涉及一种可视化系统，其包括设计成独立的或容纳在较大内窥镜的仪器通道内的小规模视觉导管。 视觉导管具有可在成像通道内的成像装置，工作通道和可插入到导管的工作通道中以提供位置跟踪的电磁传感器元件。 导管的工作通道还提供治疗和诊断工具的通路。

公开(公告)号：US20070225559A1

公开(公告)日：2007-09-27

申请号：US11385320

申请日：2006-03-21

申请人： Claude Clerc ,  John Hutchins ,  Alexandra Rousseau ,  F. Headley

发明人： Claude Clerc ,  John Hutchins ,  Alexandra Rousseau ,  F. Headley

IPC分类号： A61B1/00 ,  A61B1/04

CPC分类号： A61B1/018 ,  A61B1/2676 ,  A61B5/065

摘要： The present invention is a visualization system including a small gauge vision catheter that is designed to be stand-alone or received within an instrument channel of a larger endoscope. The vision catheter has imaging means disposable within an imaging channel, a working channel, and an electromagnetic sensor element insertable into the working channel of the catheter to provide position tracking. The working channel of the catheter also provides access for therapeutic and diagnostic tools.

摘要翻译： 本发明是一种可视化系统，其包括设计成独立的或容纳在较大内窥镜的仪器通道内的小规模视觉导管。 视觉导管具有可在成像通道内的成像装置，工作通道和可插入到导管的工作通道中以提供位置跟踪的电磁传感器元件。 导管的工作通道还提供治疗和诊断工具的通路。