公开(公告)号：US20080051702A1

公开(公告)日：2008-02-28

申请号：US11726608

申请日：2007-03-22

申请人： Robert A. Herrmann ,  John J. Damarati ,  Sepideh Hashemi ,  Wendy Naimark ,  Barry N. Gellman ,  Robert Rioux ,  Alexandra Rousseau ,  Raymond Lareau

发明人： Robert A. Herrmann ,  John J. Damarati ,  Sepideh Hashemi ,  Wendy Naimark ,  Barry N. Gellman ,  Robert Rioux ,  Alexandra Rousseau ,  Raymond Lareau

IPC分类号： A61K31/573

CPC分类号： A61K31/573

摘要： Methods for the treatment of asthma are provided, which comprise: (a) providing an implantable or insertable medical device that comprises an asthma treatment agent; and (b) inserting or implanting the medical device within the lungs (e.g., the trachea or the bronchial tree) of a patient, whereupon the therapeutic agent is delivered to the patient in an amount effective to reduce or eliminate the symptoms of asthma. Also disclosed herein are medical devices and kits for carrying out such methods.

摘要翻译： 提供了治疗哮喘的方法，其包括：（a）提供包含哮喘治疗剂的可植入或可插入的医疗装置; 和（b）将医疗装置插入或植入患者的肺部（例如，气管或支气管树）中，于是将治疗剂以有效减少或消除哮喘症状的量递送给患者。 本文还公开了用于执行这些方法的医疗装置和套件。

公开(公告)号：US20120231047A1

公开(公告)日：2012-09-13

申请号：US13480227

申请日：2012-05-24

申请人： Robert A. Herrmann ,  John J. Damarati ,  Sepideh Hashemi ,  Wendy Naimark ,  Barry N. Gellman ,  Robert Rioux ,  Alexandra Rousseau ,  Raymond Lareau

发明人： Robert A. Herrmann ,  John J. Damarati ,  Sepideh Hashemi ,  Wendy Naimark ,  Barry N. Gellman ,  Robert Rioux ,  Alexandra Rousseau ,  Raymond Lareau

IPC分类号： A61K31/56 ,  A61K47/02 ,  A61P11/06 ,  A61M37/00 ,  A61P35/00 ,  A61P21/02 ,  A61M25/10 ,  A61K9/00 ,  A61P29/00

CPC分类号： A61K31/573

摘要： Methods for the treatment of asthma are provided, which comprise: (a) providing an implantable or insertable medical device that comprises an asthma treatment agent; and (b) inserting or implanting the medical device within the lungs (e.g., the trachea or the bronchial tree) of a patient, whereupon the therapeutic agent is delivered to the patient in an amount effective to reduce or eliminate the symptoms of asthma. Also disclosed herein are medical devices and kits for carrying out such methods.

摘要翻译： 提供了治疗哮喘的方法，其包括：（a）提供包含哮喘治疗剂的可植入或可插入的医疗装置; 和（b）将医疗装置插入或植入患者的肺部（例如，气管或支气管树）中，于是将治疗剂以有效减少或消除哮喘症状的量递送给患者。 本文还公开了用于执行这些方法的医疗装置和套件。

公开(公告)号：US08133240B2

公开(公告)日：2012-03-13

申请号：US11773936

申请日：2007-07-05

申请人： John J. Damarati

发明人： John J. Damarati

IPC分类号： A61B17/10

CPC分类号： A61B17/122 ,  A61B17/1227 ,  A61B17/1285 ,  A61B2017/00296 ,  A61B2017/00867 ,  A61B2017/2905 ,  A61B2017/2924 ,  Y10T29/53783

摘要： Spring clips are arranged end to end in a cavity of an inner shaft. Such shaft slides within an outer shaft, and a pusher member slides in the cavity behind the clips. The clips have jaws biased together, but which are wedged apart by an opener as the pusher is moved distally. An opened clip is ejected by relative movement of the inner and outer shafts to clamp body tissue at a desired site.

摘要翻译： 弹簧夹端对端设置在内轴的空腔中。 这种轴在外轴内滑动，并且推动构件在夹子后面的空腔中滑动。 夹子具有偏压在一起的爪，但是当推动器向远侧移动时，它们被开启器楔入。 通过内轴和外轴的相对运动来弹出打开的夹子，以将身体组织夹紧在期望的位置。

公开(公告)号：US07341564B2

公开(公告)日：2008-03-11

申请号：US10132879

申请日：2002-04-24

申请人： Aaron Zwiefel ,  John J. Damarati ,  Masaru Yokomaku ,  Keisuke Hirai ,  Hideko Goto ,  Kumiko Tatami ,  Eiko Hikage

发明人： Aaron Zwiefel ,  John J. Damarati ,  Masaru Yokomaku ,  Keisuke Hirai ,  Hideko Goto ,  Kumiko Tatami ,  Eiko Hikage

IPC分类号： A61B10/06

CPC分类号： A61B10/06 ,  A61B2017/00907 ,  A61B2017/320064

摘要： An endoscopic biopsy device having an outer sheath that is transparent, at least along a portion thereof, to allow visualization of at least a portion of the inside of the device. A distal portion of the outer sheath may be relatively more opaque or relatively less reflective to avoid glare that may otherwise result due to the sheath reflecting light from the endoscopic light source.

摘要翻译： 至少沿其一部分具有透明的外护套的内窥镜活检装置，以允许装置内部的至少一部分可视化。 外护套的远侧部分可以是相对更不透明或相对更少的反射性，以避免由于外壳反射来自内窥镜光源的光而导致的眩光。

公开(公告)号：US06679894B2

公开(公告)日：2004-01-20

申请号：US10281900

申请日：2002-10-24

申请人： John J. Damarati

发明人： John J. Damarati

IPC分类号： A61B1700

CPC分类号： A61B17/122 ,  A61B17/1227 ,  A61B17/1285 ,  A61B2017/00296 ,  A61B2017/00867 ,  A61B2017/2905 ,  A61B2017/2924 ,  Y10T29/53783

摘要： Spring clips are arranged end to end in a cavity of an inner shaft. Such shaft slides within an outer shaft, and a pusher member slides in the cavity behind the clips. The clips have jaws biased together, but which are wedged apart by an opener as the pusher is moved distally. An opened clip is ejected by relative movement of the inner and outer shafts to clamp body tissue at a desired site.

摘要翻译： 弹簧夹端对端设置在内轴的空腔中。 这种轴在外轴内滑动，并且推动构件在夹子后面的空腔中滑动。 夹子具有偏压在一起的爪，但是当推动器向远侧移动时，它们被开启器楔入。 通过内轴和外轴的相对运动来弹出打开的夹子，以将身体组织夹紧在期望的位置。

公开(公告)号：US09301862B2

公开(公告)日：2016-04-05

申请号：US11341540

申请日：2006-01-27

申请人： Gary A. Jordan ,  Claude O. Clerc ,  Paul K. Norton ,  Michael Zupkofska ,  John J. Damarati

发明人： Gary A. Jordan ,  Claude O. Clerc ,  Paul K. Norton ,  Michael Zupkofska ,  John J. Damarati

IPC分类号： A61F2/95 ,  A61F2/90 ,  A61F2/88

CPC分类号： A61F2/90 ,  A61F2/885 ,  A61F2/95 ,  A61F2002/9511 ,  A61F2002/9528 ,  A61F2002/9534 ,  A61F2210/0014 ,  A61F2210/0057 ,  A61F2230/0069 ,  A61F2250/0039

摘要： An implantable stent includes a stent retrieval member for repositioning or retrieval of the stent after it has been implanted into a bodily lumen. The stent includes a distensible tubular stent having a tubular structure having a tubular wall defined by an interior surface and an exterior surface and having opposed open ends; and a stent retrieval member comprising an elongate member comprising a generally circular perimetric base and a shaped projection having first and second spaced apart members extending acutely or perpendicularly from the base and connected by an apical portion. Force exerted on the shaped projection causes contraction or expansion of the circular base. The circular base is securably attached to one of the open ends of the stent, and the shaped projection extends longitudinally beyond this open end of the stent.

公开(公告)号：US08936610B2

公开(公告)日：2015-01-20

申请号：US13369503

申请日：2012-02-09

申请人： John J. Damarati

发明人： John J. Damarati

IPC分类号： A61B17/10 ,  A61B17/122 ,  A61B17/128 ,  A61B17/00 ,  A61B17/29

CPC分类号： A61B17/122 ,  A61B17/1227 ,  A61B17/1285 ,  A61B2017/00296 ,  A61B2017/00867 ,  A61B2017/2905 ,  A61B2017/2924 ,  Y10T29/53783

摘要： Spring clips are arranged end to end in a cavity of an inner shaft. Such shaft slides within an outer shaft, and a pusher member slides in the cavity behind the clips. The clips have jaws biased together, but which are wedged apart by an opener as the pusher is moved distally. An opened clip is ejected by relative movement of the inner and outer shafts to clamp body tissue at a desired site.

公开(公告)号：US07001399B2

公开(公告)日：2006-02-21

申请号：US10723433

申请日：2003-11-26

申请人： John J. Damarati

发明人： John J. Damarati

IPC分类号： A61B17/00

CPC分类号： A61B17/122 ,  A61B17/1227 ,  A61B17/1285 ,  A61B2017/00296 ,  A61B2017/00867 ,  A61B2017/2905 ,  A61B2017/2924 ,  Y10T29/53783

摘要： Spring clips are arranged end to end in a cavity of an inner shaft. Such shaft slides within an outer shaft, and a pusher member slides in the cavity behind the clips. The clips have jaws biased together, but which are wedged apart by an opener as the pusher is moved distally. An opened clip is ejected by relative movement of the inner and outer shafts to clamp body tissue at a desired site.