公开(公告)号：US20080188745A1

公开(公告)日：2008-08-07

申请号：US11794930

申请日：2005-08-02

申请人： Wenzhi Chen ,  Zhibiao Wang ,  Zhilong Wang ,  Tao Lin ,  Chunliang Zhao

发明人： Wenzhi Chen ,  Zhibiao Wang ,  Zhilong Wang ,  Tao Lin ,  Chunliang Zhao

IPC分类号： A61N7/00

CPC分类号： A61N7/02 ,  A61B2090/378

摘要： The apparatus for high-intensity focused ultrasound therapy of the present invention usually comprises a ultrasound transducer, an image acquisition device, a driving unit for driving said ultrasound transducer and mechanical drive means for mechanically driving said ultrasound transducer and image acquisition device together. Additionally, this apparatus for high-intensity focused ultrasound therapy further comprises a signal processing unit connected to image acquisition device for receiving and saving the original images of the target area prior to treatment and for receiving and saving the images of the target area in a certain time during high-intensity focused ultrasound (HIFU) treatment and for evaluating the therapeutic effects according to the images of the target area before and after treatment, and a control unit respectively connected to signal processing unit, driving unit and mechanical driving means. When the signal processing unit judges that the therapeutic requirements have been met, the control unit controls the driving unit and mechanical driving means to stop the working of ultrasound transducer and when the signal processing unit judges that the therapeutic requirements have not been met, the control unit controls the driving unit and mechanical driving means to make the ultrasound transducer continue to work.

摘要翻译： 本发明的高强度聚焦超声治疗装置通常包括超声波换能器，图像采集装置，用于驱动所述超声波换能器的驱动单元和用于将所述超声换能器和图像采集装置机械驱动在一起的机械驱动装置。 此外，该高强度聚焦超声治疗装置还包括连接到图像获取装置的信号处理单元，用于在处理之前接收和保存目标区域的原始图像，并且在一定程度上接收和保存目标区域的图像 在高强度聚焦超声（HIFU）治疗期间的时间和根据治疗前后的目标区域的图像来评估治疗效果的时间，以及分别连接到信号处理单元，驱动单元和机械驱动装置的控制单元。 当信号处理单元判断满足治疗要求时，控制单元控制驱动单元和机械驱动装置来停止超声波换能器的工作，并且当信号处理单元判断出没有满足治疗要求时，控制 单元控制驱动单元和机械驱动装置，以使超声换能器继续工作。

公开(公告)号：US20090054772A1

公开(公告)日：2009-02-26

申请号：US11883097

申请日：2005-08-26

申请人： Tao Lin ,  Wenzhi Chen ,  Yingang Wen ,  Zhibiao Wang ,  Zhilong Wang

发明人： Tao Lin ,  Wenzhi Chen ,  Yingang Wen ,  Zhibiao Wang ,  Zhilong Wang

IPC分类号： A61B8/00 ,  A61N7/00

CPC分类号： A61N7/02 ,  A61B90/14 ,  A61B2090/378

摘要： The present invention pertains to an ultrasound therapy system and more specifically, to a high-intensity focused ultrasound (HIFU) therapy apparatus guided by image registration and fusion method. The therapy system of the present invention comprises a central control means; an acoustic energy applicator; a mechanical driving and locating means of said acoustic energy applicator; a real-time B-mode ultrasound image guiding device. Further the therapy system of the present invention comprises an immobilization means for body position. By the help of this immobilization means for body position, real-time B-mode ultrasound images can be registered with diagnosis images, and then on the basis of registration, said B-mode ultrasound images are fused with said diagnosis images for guiding said therapy. Comparing to the existed technical solutions in this field, the present invention has effectively solved the difficult problems in high-intensity focused ultrasound therapy and particularly for tumor treatment with a low cost. And it provides a very practical technical solution, which can be easily applied to clinical treatment of tumors.

摘要翻译： 本发明涉及一种超声治疗系统，更具体地涉及由图像配准和融合方法引导的高强度聚焦超声（HIFU）治疗装置。 本发明的治疗系统包括中央控制装置; 声能施加器; 所述声能施加器的机械驱动和定位装置; 实时B模式超声图像引导装置。 此外，本发明的治疗系统包括用于身体位置的固定装置。 借助于该身体位置的固定装置，实时B模式超声图像可以与诊断图像一起登记，然后在登记的基础上，将所述B模式超声图像与用于引导所述治疗的所述诊断图像融合 。 与现有技术方案相比，本发明有效地解决了高强度聚焦超声治疗中的困难问题，特别是低成本的肿瘤治疗。 它提供了一个非常实用的技术解决方案，可以很容易地应用于肿瘤的临床治疗。

公开(公告)号：US08375937B2

公开(公告)日：2013-02-19

申请号：US12680384

申请日：2008-06-20

申请人： Wenzhi Chen ,  Diyuan Hu ,  Chunliang Zhao

发明人： Wenzhi Chen ,  Diyuan Hu ,  Chunliang Zhao

IPC分类号： A61F5/24 ,  A61B8/00

CPC分类号： A61N7/00 ,  A61B17/2251

摘要： The present invention discloses an intestinal tract pushing apparatus for ultrasonic therapy. The intestinal tract pushing apparatus includes a pushing member and an acoustically transparent member. One end of said acoustically transparent member is connected to a buckling strip, and the other end of the acoustically transparent member is connected to an adhesive strip. The acoustically transparent member is bound to the human abdomen by virtue of the adhesive fastening of the buckling strip and the adhesive strip. The pushing member employs a hydraulic system.

摘要翻译： 本发明公开了一种用于超声波治疗的肠道推送装置。 肠道推送装置包括推动构件和声透明构件。 所述透声构件的一端连接到弯曲带，声透明构件的另一端连接到粘合带。 通过屈曲条和粘合带的粘合固定，声透明构件与人腹部结合。 推动构件采用液压系统。

公开(公告)号：US20100307486A1

公开(公告)日：2010-12-09

申请号：US12680384

申请日：2008-06-20

申请人： Wenzhi Chen ,  Diyuan Hu ,  Chunliang Zhao

发明人： Wenzhi Chen ,  Diyuan Hu ,  Chunliang Zhao

IPC分类号： A61B17/00

CPC分类号： A61N7/00 ,  A61B17/2251

摘要： The present invention discloses an intestinal tract pushing apparatus for ultrasonic therapy. The intestinal tract pushing apparatus includes a pushing member and an acoustically transparent member. One end of said acoustically transparent member is connected to a buckling strip, and the other end of the acoustically transparent member is connected to an adhesive strip. The acoustically transparent member is bound to the human abdomen by virtue of the adhesive fastening of the buckling strip and the adhesive strip. The pushing member employs a hydraulic system.

摘要翻译： 本发明公开了一种用于超声波治疗的肠道推送装置。 肠道推送装置包括推动构件和声透明构件。 所述透声构件的一端连接到弯曲带，声透明构件的另一端连接到粘合带。 通过屈曲条和粘合带的粘合固定，声透明构件与人腹部结合。 推动构件采用液压系统。

公开(公告)号：US20080275330A1

公开(公告)日：2008-11-06

申请号：US11883096

申请日：2005-08-31

申请人： Mu Mu ,  Wenzhi Chen ,  Hai Wang ,  Long Wang

发明人： Mu Mu ,  Wenzhi Chen ,  Hai Wang ,  Long Wang

IPC分类号： A61B5/055 ,  A61N7/00

CPC分类号： A61N7/02 ,  A61B34/70 ,  A61B2017/00084 ,  A61B2090/374

摘要： This invention provides a MRI guided ultrasound therapy apparatus. It comprises a static field magnet adapted to apply a static magnetic field in an magnetic resonance volume at a predetermined disposition; at least one ultrasound energy applicator adapted to apply energy within an energy application zone at a predetermined disposition; and The mechanical positioning means for moving said ultrasound energy applicator to position the applicator so that the energy application zone intersects said magnetic resonance volume within said region of the subject. In that apparatus, the static field magnet is open at both ends or open at side. The sided open is upward or downward and the mechanical positioning means of this ultrasound energy applicator is close to and is located outside of this sided open. This invention reduces the space limitation for the mechanical positioning means of the ultrasound transducer. Meanwhile, the non-magnetic requirement on the mechanical positioning means become less greatly and particularly the problem of interference from magnetic field produced by working current of the transducer power cord to MRI system can be solved.

摘要翻译： 本发明提供一种MRI引导超声治疗装置。 它包括静磁场磁体，其适于以预定的配置在磁共振体积中施加静磁场; 至少一个超声能量施加器适于在预定的配置下在能量施加区域内施加能量; 以及机械定位装置，用于移动所述超声能量施加器以定位所述施加器，使得所述能量施加区域与所述对象的所述区域内的所述磁共振体积相交。 在该装置中，静磁场磁体在两端敞开，侧面开放。 侧面打开是向上或向下的，并且该超声能量施加器的机械定位装置接近并位于该侧面打开的外侧。 本发明减小了超声波换能器的机械定位装置的空间限制。 同时，对机械定位装置的非磁性要求变得不那么大，特别是可以解决由换能器电源线的工作电流产生的磁场与MRI系统的干扰问题。

公开(公告)号：US20100056925A1

公开(公告)日：2010-03-04

申请号：US12515830

申请日：2005-02-13

申请人： Chunyan Zhang ,  Wenzhi Chen ,  Siyuan Yan

发明人： Chunyan Zhang ,  Wenzhi Chen ,  Siyuan Yan

IPC分类号： A61B8/00

CPC分类号： A61N7/02 ,  A61B2018/00023 ,  A61N2007/0013 ,  A61N2007/006 ,  A61N2007/0078 ,  A61N2007/027

摘要： An ultrasonic therapeutic device capable of multipoint transmitting includes a substrate (5), on which an ultrasonic transducer array is arranged. Wherein, each of the ultrasonic transducers in the ultrasonic transducer array can independently focus. The device of the present invention has a simple structure and a good focusing performance. There is no interference among the ultrasonic transducers. Therefore, the energy of ultrasonic wave is transmitted by predetermined route with high utilization ratio.

摘要翻译： 能够进行多点传输的超声治疗装置包括：基板（5），其上布置有超声波换能器阵列。 其中，超声波换能器阵列中的每个超声波换能器可以独立聚焦。 本发明的装置具有简单的结构和良好的聚焦性能。 超声波换能器之间没有干扰。 因此，超声波的能量通过具有高利用率的预定路径传输。

公开(公告)号：US08224420B2

公开(公告)日：2012-07-17

申请号：US11883096

申请日：2005-08-31

申请人： Mu Mu ,  Wenzhi Chen ,  Hai Wang ,  Long Wang

发明人： Mu Mu ,  Wenzhi Chen ,  Hai Wang ,  Long Wang

IPC分类号： A61B5/055

CPC分类号： A61N7/02 ,  A61B34/70 ,  A61B2017/00084 ,  A61B2090/374

摘要： This invention provides a MRI guided ultrasound therapy apparatus. It comprises a static field magnet adapted to apply a static magnetic field in an magnetic resonance volume at a predetermined disposition; at least one ultrasound energy applicator adapted to apply energy within an energy application zone at a predetermined disposition; and The mechanical positioning means for moving said ultrasound energy applicator to position the applicator so that the energy application zone intersects said magnetic resonance volume within said region of the subject. In that apparatus, the static field magnet is open at both ends or open at side. The sided open is upward or downward and the mechanical positioning means of this ultrasound energy applicator is close to and is located outside of this sided open. This invention reduces the space limitation for the mechanical positioning means of the ultrasound transducer. Meanwhile, the non-magnetic requirement on the mechanical positioning means become less greatly and particularly the problem of interference from magnetic field produced by working current of the transducer power cord to MRI system can be solved.

摘要翻译： 本发明提供一种MRI引导超声治疗装置。 它包括静磁场磁体，其适于以预定的配置在磁共振体积中施加静磁场; 至少一个超声能量施加器适于在预定的配置下在能量施加区域内施加能量; 以及机械定位装置，用于移动所述超声能量施加器以定位所述施加器，使得所述能量施加区域与所述对象的所述区域内的所述磁共振体积相交。 在该装置中，静磁场磁体在两端敞开，侧面开放。 侧面打开是向上或向下的，并且该超声能量施加器的机械定位装置接近并位于该侧面打开的外侧。 本发明减小了超声波换能器的机械定位装置的空间限制。 同时，对机械定位装置的非磁性要求变得不那么大，特别是可以解决由换能器电源线的工作电流产生的磁场与MRI系统的干扰问题。