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    Extracellular matrix based gastroesophageal junction reinforcement device
    2.
    发明授权
    Extracellular matrix based gastroesophageal junction reinforcement device 有权
    基于细胞外基质的胃食管结合加强装置

    公开(公告)号：US08927003B2

    公开(公告)日：2015-01-06

    申请号：US13108074

    申请日：2011-05-16

    申请人： Stephen F. Badylak ,  Thomas W. Gilbert ,  Alejandro Nieponice

    发明人： Stephen F. Badylak ,  Thomas W. Gilbert ,  Alejandro Nieponice

    IPC分类号： A61L27/36 ,  A61K35/38 ,  A61L27/38

    CPC分类号： A61L27/3679 ,  A61F2/04 ,  A61F2002/044 ,  A61K35/38 ,  A61L27/362 ,  A61L27/3629 ,  A61L27/3633 ,  A61L27/3882 ,  A61L2430/22

    摘要： Provided are medical devices for implantation in patients having suffered the loss of or damage to at least part of their esophagus. The medical device connects the esophagus or remaining part thereof with the stomach to form a gastro-esophageal junction that promotes healing and encourages new host tissue growth while distributing the load and decreasing tension at the anastomotic site. The medical device comprises extracellular matrix shaped into a conformation that more closely approximates the geometry of the native gastro-esophageal junction than does direct attachment of the stomach to the shortened esophagus. Molds useful in manufacturing the medical device and methods of use of the device are also described herein.

    摘要翻译： 提供用于植入患有至少部分食管的患者的医疗装置。 医疗装置将食道或其余部分与胃连接以形成胃食管连接处，其在分配负荷并减少吻合部位的张力的同时促进愈合并促进新的宿主组织生长。 医疗装置包括细胞外基质成形为更接近天然胃食管结合物的几何形状的构象，而不是将胃直接附着于缩短的食道。 在本文中还描述了用于制造医疗装置的模具和装置的使用方法。

    EXTRACELLULAR MATRIX BASED GASTROESOPHAGEAL JUNCTION REINFORCEMENT DEVICE
    3.
    发明申请
    EXTRACELLULAR MATRIX BASED GASTROESOPHAGEAL JUNCTION REINFORCEMENT DEVICE 有权
    基于细胞基质的胃肠道结节加强装置

    公开(公告)号：US20110288654A1

    公开(公告)日：2011-11-24

    申请号：US13108074

    申请日：2011-05-16

    申请人： Stephen F. Badylak ,  Thomas W. Gilbert ,  Alejandro Nieponice

    发明人： Stephen F. Badylak ,  Thomas W. Gilbert ,  Alejandro Nieponice

    IPC分类号： A61F2/04

    CPC分类号： A61L27/3679 ,  A61F2/04 ,  A61F2002/044 ,  A61K35/38 ,  A61L27/362 ,  A61L27/3629 ,  A61L27/3633 ,  A61L27/3882 ,  A61L2430/22

    摘要： Provided are medical devices for implantation in patients having suffered the loss of or damage to at least part of their esophagus. The medical device connects the esophagus or remaining part thereof with the stomach to form a gastro-esophageal junction that promotes healing and encourages new host tissue growth while distributing the load and decreasing tension at the anastomotic site. The medical device comprises extracellular matrix shaped into a conformation that more closely approximates the geometry of the native gastro-esophageal junction than does direct attachment of the stomach to the shortened esophagus. Molds useful in manufacturing the medical device and methods of use of the device are also described herein.

    摘要翻译： 提供用于植入患有至少部分食管的患者的医疗装置。 医疗装置将食道或其余部分与胃连接以形成胃食管连接处，其在分配负荷并减少吻合部位的张力的同时促进愈合并促进新的宿主组织生长。 医疗装置包括细胞外基质成形为更接近天然胃食管结合物的几何形状的构象，而不是将胃直接附着于缩短的食道。 在本文中还描述了用于制造医疗装置的模具和装置的使用方法。

    Children's learning toy
    6.
    发明授权
    Children's learning toy 失效
    儿童学习玩具

    公开(公告)号：US06176704B1

    公开(公告)日：2001-01-23

    申请号：US09379250

    申请日：1999-08-23

    申请人： Thomas W. Gilbert

    发明人： Thomas W. Gilbert

    IPC分类号： G09B1700

    CPC分类号： G09B17/02 ,  G09B17/00

    摘要： A learning toy based upon the concept of design or pattern formation is disclosed. The toy is comprised of a tray having a transparent bottom and a plurality of blocks which are arrangeable in the tray to form a design or pattern. Each block is painted with a primary color on four of its surfaces while the fifth surface of the block is painted with two of the primary colors with the boundary therebetween being on a diagonal across the surface of the block and the sixth surface of the block is painted with the other two primary colors with the boundary therebetween being on a diagonal across the surface of the block. When the blocks are arranged in the tray to form a design or pattern, a juxtaposition of dark and light colors is created on the top surface of the blocks and an “opposite” design or pattern is formed on the bottom surfaces of the blocks which can be viewed through the transparent bottom surface of the tray.

    摘要翻译： 公开了一种基于设计或图案形成概念的学习玩具。 该玩具由具有透明底部的托盘和可布置在托盘中以形成设计或图案的多个块组成。 每个块在其四个表面上涂上原色，而块的第五表面涂有两种原色，其间的边界在块的表面上在对角线上，块的第六表面是 用其他两种原色涂漆，其间的边界在块的表面上在对角线上。 当块被布置在托盘中以形成设计或图案时，在块的顶表面上产生暗色和浅色的并置，并且在块的底表面上形成“相对”的设计或图案，其可以 通过托盘的透明底面观察。