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7 条记录 (耗时 0.03 秒)

    Novel 1,2,4-benzotriazine-1,4-dioxides
    1.
    发明申请
    Novel 1,2,4-benzotriazine-1,4-dioxides 有权
    新的1,2,4-苯并三嗪-1,4-二氧化物

    公开(公告)号：US20070197534A1

    公开(公告)日：2007-08-23

    申请号：US10590796

    申请日：2005-03-01

    申请人： William Denny ,  Michael Hay ,  Kevin Hicks ,  Frederik Pruijn ,  William Wilson ,  Karin Pchalek

    发明人： William Denny ,  Michael Hay ,  Kevin Hicks ,  Frederik Pruijn ,  William Wilson ,  Karin Pchalek

    IPC分类号： C07D253/08 ,  A61K31/28 ,  A61K31/53

    CPC分类号： C07D253/10 ,  C07D253/08 ,  C07D401/12

    摘要： The present invention provides a simplified set of characteristics that can be used to select 1,2,4 benzotriazine 1,4 dioxide compounds (TPZ analogues) with therapeutic activity against hypoxic cells in human tumour xenografts, and to further provide a novel class of 1,2,4-benzotriazine-1,4-dioxides (TPZ analogues) with predicted in vivo activity against tumours, to their preparation, and to their use as hypoxia-selective cytotoxic drugs and radiosensitizers for cancer therapy, both alone or in combination with radiation and/or other anticancer drugs.

    摘要翻译： 本发明提供了可用于选择具有对人类肿瘤异种移植物中的缺氧细胞具有治疗活性的1,2,4苯并三嗪二氧化物化合物（TPZ类似物）的简化特征集，并进一步提供新的1类 ，具有预测的针对肿瘤的体内活性的2,4-苯并三嗪-1,4-二氧化物（TPZ类似物），其制备及其作为用于癌症治疗的缺氧选择性细胞毒性药物和放射增敏剂的用途，单独或与 辐射和/或其他抗癌药物。

    EVALUATING RISK OF INFORMATION MISMANAGEMENT IN COMPUTER STORAGE
    3.
    发明申请
    EVALUATING RISK OF INFORMATION MISMANAGEMENT IN COMPUTER STORAGE 审中-公开
    评估计算机存储信息错误的风险

    公开(公告)号：US20090222415A1

    公开(公告)日：2009-09-03

    申请号：US12041560

    申请日：2008-03-03

    申请人： Yasuyuki MIMATSU ,  Michael Hay ,  Keiko Harada

    发明人： Yasuyuki MIMATSU ,  Michael Hay ,  Keiko Harada

    IPC分类号： G06F7/06 ,  G06F17/30

    CPC分类号： G06F21/62 ,  G06F21/577

    摘要： Method and system of evaluating overall risk of mismanagement of information contained in a file and its copies on a storage system. The method collects information about storage availability, accessibility, preservation and searchability of the data in each file. The method quantifies the collected information and allows a user to define risk criteria and assign risk values for each aspect of the collected information. The file risk of mismanagement of a specified data file is evaluated and compared against a threshold to determine whether or not the file is well-managed. If the file has copies, the file risk of mismanagement of each of the copies is also evaluated to obtain the risk of mismanagement of information in all of the copies. Copies with high risks of mismanagement may be discarded to lower the risk of mismanagement of the information. An administrator of a storage system may perform the method.

    摘要翻译： 对文件中包含的信息管理不善的整体风险及存储系统的副本进行评估的方法和系统。 该方法收集有关每个文件中的数据的存储可用性，可访问性，保存和可搜索性的信息。 该方法量化收集的信息，并允许用户定义风险标准，并为收集的信息的每个方面分配风险值。 评估指定数据文件管理不当的文件风险，并与阈值进行比较，以确定文件是否管理良好。 如果该文件有副本，则还会对每个副本的管理不善造成的文件风险进行评估，以获得所有副本中信息管理不善的风险。 复制管理不善的高风险可能会被丢弃，以降低信息管理不善的风险。 存储系统的管理员可以执行该方法。

    COMPUTER SYSTEM AND STORAGE CAPACITY EXTENSION METHOD
    5.
    发明申请
    COMPUTER SYSTEM AND STORAGE CAPACITY EXTENSION METHOD 审中-公开
    计算机系统和存储容量扩展方法

    公开(公告)号：US20120102080A1

    公开(公告)日：2012-04-26

    申请号：US12746216

    申请日：2010-05-20

    申请人： Yasuhiro Kirihata ,  Michael Hay ,  Kota Yamaguchi

    发明人： Yasuhiro Kirihata ,  Michael Hay ,  Kota Yamaguchi

    IPC分类号： G06F17/30

    CPC分类号： H04L67/1097 ,  G06F16/1774 ,  G06F16/1827 ,  G06F21/604 ,  G06F21/6218 ,  G06F2221/2141 ,  G06F2221/2147

    摘要： Provided is a computer system configured so that security compliance problems can be avoided and an access control model which can be uniquely customized can be implemented by extending the storage capacity to an external storage service by means of integrated management of an existing NAS(s) and the external storage service, and controlling the optimum data placement according to the confidentiality and importance level of data.In a computer system according to this invention, a local storage system includes an extended server for integrating a NAS(s) existing in the local storage system with an external storage service and thereby providing a client with a storage area as a single virtual NAS.

    摘要翻译： 提供了一种被配置为使得可以避免安全合规性问题的计算机系统，并且可以通过对现有NAS的集成管理将存储容量扩展到外部存储服务来实现可以独特定制的访问控制模型，并且 外部存储服务，并根据数据的机密性和重要性级别控制最佳数据布局。 在根据本发明的计算机系统中，本地存储系统包括用于将存在于本地存储系统中的NAS与外部存储服务集成的扩展服务器，从而向客户端提供作为单个虚拟NAS的存储区域。

    Search system that returns query results as files in a file system
    6.
    发明申请
    Search system that returns query results as files in a file system 审中-公开
    搜索系统将查询结果作为文件系统中的文件返回

    公开(公告)号：US20060294116A1

    公开(公告)日：2006-12-28

    申请号：US11166063

    申请日：2005-06-23

    申请人： Michael Hay

    发明人： Michael Hay

    IPC分类号： G06F7/00

    CPC分类号： G06F16/156

    摘要： Search systems that perform a search or inquiry to find information elements that satisfy some searching criteria usually return some indication of these information elements in a form that can be viewed or accessed only within the search system itself. An improved system presents the information elements as files in a conventional file system so that the search results can be viewed or accessed by essentially any program or other facility that is capable of accessing conventional files.

    摘要翻译： 执行搜索或查询以查找满足一些搜索条件的信息元素的搜索系统通常以仅可以在搜索系统本身内查看或访问的形式返回这些信息元素的一些指示。 改进的系统将信息元素呈现为传统文件系统中的文件，使得可以通过基本上能够访问常规文件的任何程序或其他设施来查看或访问搜索结果。

    Friction slide
    7.
    发明申请
    Friction slide 失效
    摩擦滑块

    公开(公告)号：US20060066190A1

    公开(公告)日：2006-03-30

    申请号：US11238941

    申请日：2005-09-29

    申请人： Michael Hay

    发明人： Michael Hay

    IPC分类号： A47B88/00 ,  A47B95/00

    CPC分类号： A47B88/49 ,  A47B88/40 ,  A47B88/497 ,  A47B2210/0059

    摘要： The apparatus and methods reduce the force needed to open and close a drawer, as well as reduce noise generated by friction slide mechanisms when the drawer is opened and closed. A drawer slide mechanism includes a first elongated track, an elongated rail, and a low friction material. The rail is telescopically received by the track, by which a path of motion is defined for the rail. The rail remains at least partially received by the track along the entire path of motion of the rail. In addition, the low friction material is disposed between the track and the rail such that the low friction material remains at least partially disposed between the track and the rail throughout the entire path of motion.

    摘要翻译： 该装置和方法减少了打开和关闭抽屉所需的力，并且减少了当抽屉打开和关闭时由摩擦滑动机构产生的噪音。 抽屉滑动机构包括第一细长轨道，细长轨道和低摩擦材料。 轨道由轨道可伸缩地接收，通过该轨道为轨道定义运动路径。 轨道至少部分地沿着轨道的整个运动路径被轨道接收。 此外，低摩擦材料设置在轨道和轨道之间，使得低摩擦材料至少部分地设置在轨道和轨道之间的整个运动路径上。