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1.发明申请Compositions and methods for treating disease utilizing a combination of radioactive therapy and cell-cycle inhibitors 审中-公开使用放射性治疗和细胞周期抑制剂的组合治疗疾病的组合物和方法公开(公告)号：US20080058579A1
公开(公告)日：2008-03-06
申请号：US11594022
申请日：2006-11-06
申请人： William Hunter , David Gravett , Richard Liggins , Troy Loss , Arpita Maiti , Philip Toleikis
发明人： William Hunter , David Gravett , Richard Liggins , Troy Loss , Arpita Maiti , Philip Toleikis
IPC分类号： A61M36/12
CPC分类号： A61N5/1027 , A61K41/0038 , A61K49/0002 , A61K49/222 , A61K51/1282 , A61L31/18 , A61N2005/1019 , A61N2005/1023 , A61K2300/00
摘要： Disclosed herein are therapeutic devices, compositions and methods for treating proliferative diseases. For example, within one aspect of the invention therapeutic devices are provided, comprising a device that locally administers radiation and a cell-cycle inhibitor
摘要翻译： 本文公开了治疗增殖性疾病的治疗装置，组合物和方法。 例如，在本发明的一个方面，提供治疗装置，其包括局部施用辐射的装置和细胞周期抑制剂
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公开(公告)号：US20050196421A1
公开(公告)日：2005-09-08
申请号：US11001417
申请日：2004-12-01
申请人： William Hunter , Philip Toleikis , David Gravett , Arpita Maiti , Richard Liggins , Aniko Takacs-Cox , Rui Avelar , Troy Loss
发明人： William Hunter , Philip Toleikis , David Gravett , Arpita Maiti , Richard Liggins , Aniko Takacs-Cox , Rui Avelar , Troy Loss
IPC分类号： A61B19/00 , A61F2/00 , A61F2/08 , A61F2/28 , A61F2/44 , A61K9/14 , A61K31/337 , A61K31/365 , A61K31/4745 , A61K31/704 , A61K31/7048 , A61K31/7072 , A61K38/00 , A61L27/54 , A61L31/16 , A61M31/00 , A61N1/00 , A61N1/05
CPC分类号： A61K45/06 , A61L27/54 , A61L31/16 , A61L2300/404 , A61L2300/416 , A61L2300/432
摘要： Compositions comprising anti-fibrotic agent(s) and/or polymeric compositions can be used in various medical applications including the prevention of surgical adhesions, treatment of inflammatory arthritis, treatment of scars and keloids, the treatment of vascular disease, and the prevention of cartilage loss.
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公开(公告)号：US20050187140A1
公开(公告)日：2005-08-25
申请号：US11000408
申请日：2004-11-29
申请人： William Hunter , Philip Toleikis , David Gravett , Arpita Maiti , Richard Liggins , Aniko Takacs-Cox , Rui Avelar , Troy Loss
发明人： William Hunter , Philip Toleikis , David Gravett , Arpita Maiti , Richard Liggins , Aniko Takacs-Cox , Rui Avelar , Troy Loss
IPC分类号： A61B19/00 , A61F2/00 , A61F2/08 , A61F2/28 , A61F2/44 , A61K9/14 , A61K31/337 , A61K31/365 , A61K31/4745 , A61K31/704 , A61K31/7048 , A61K31/7072 , A61K38/00 , A61L27/54 , A61L31/16 , A61M31/00 , A61N1/00 , A61N1/05
CPC分类号： A61K45/06 , A61L27/54 , A61L31/16 , A61L2300/404 , A61L2300/416 , A61L2300/432
摘要： Compositions comprising anti-fibrotic agent(s) and/or polymeric compositions can be used in various medical applications including the prevention of surgical adhesions, treatment of inflammatory arthritis, treatment of scars and keloids, the treatment of vascular disease, and the prevention of cartilage loss.
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公开(公告)号：US20050183731A1
公开(公告)日：2005-08-25
申请号：US11006908
申请日：2004-12-07
申请人： William Hunter , Philip Toleikis , David Gravett , Arpita Maiti , Richard Liggins , Aniko Takacs-Cox , Rui Avelar , Troy Loss
发明人： William Hunter , Philip Toleikis , David Gravett , Arpita Maiti , Richard Liggins , Aniko Takacs-Cox , Rui Avelar , Troy Loss
IPC分类号： A61B19/00 , A61F2/00 , A61F2/08 , A61F2/28 , A61F2/44 , A61K9/14 , A61K31/337 , A61K31/365 , A61K31/4745 , A61K31/704 , A61K31/7048 , A61K31/7072 , A61K38/00 , A61L27/54 , A61L31/16 , A61M31/00 , A61N1/00 , A61N1/05
CPC分类号： A61K45/06 , A61L27/54 , A61L31/16 , A61L2300/404 , A61L2300/416 , A61L2300/432
摘要： Compositions comprising anti-fibrotic agent(s) and/or polymeric compositions can be used in various medical applications including the prevention of surgical adhesions, treatment of inflammatory arthritis, treatment of scars and keloids, the treatment of vascular disease, and the prevention of cartilage loss.
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公开(公告)号：US20050175703A1
公开(公告)日：2005-08-11
申请号：US11006888
申请日：2004-12-07
申请人： William Hunter , Philip Toleikis , David Gravett , Arpita Maiti , Richard Liggins , Aniko Takacs-Cox , Rui Avelar , Troy Loss
发明人： William Hunter , Philip Toleikis , David Gravett , Arpita Maiti , Richard Liggins , Aniko Takacs-Cox , Rui Avelar , Troy Loss
IPC分类号： A61B19/00 , A61F2/00 , A61F2/08 , A61F2/28 , A61F2/44 , A61K9/14 , A61K31/337 , A61K31/365 , A61K31/4745 , A61K31/704 , A61K31/7048 , A61K31/7072 , A61K38/00 , A61L27/54 , A61L31/16 , A61M31/00 , A61N1/00 , A61N1/05
CPC分类号： A61K45/06 , A61L27/54 , A61L31/16 , A61L2300/404 , A61L2300/416 , A61L2300/432
摘要： Compositions comprising anti-fibrotic agent(s) and/or polymeric compositions can be used in various medical applications including the prevention of surgical adhesions, treatment of inflammatory arthritis, treatment of scars and keloids, the treatment of vascular disease, and the prevention of cartilage loss.
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公开(公告)号：US20050175665A1
公开(公告)日：2005-08-11
申请号：US11006896
申请日：2004-12-07
申请人： William Hunter , Philip Toleikis , David Gravett , Arpita Maiti , Richard Liggins , Aniko Takacs-Cox , Rui Avelar , Troy Loss
发明人： William Hunter , Philip Toleikis , David Gravett , Arpita Maiti , Richard Liggins , Aniko Takacs-Cox , Rui Avelar , Troy Loss
IPC分类号： A61B19/00 , A61F2/00 , A61F2/08 , A61F2/28 , A61F2/44 , A61K9/14 , A61K31/337 , A61K31/365 , A61K31/4745 , A61K31/704 , A61K31/7048 , A61K31/7072 , A61K38/00 , A61L27/54 , A61L31/16 , A61M31/00 , A61N1/00 , A61N1/05
CPC分类号： A61K45/06 , A61L27/54 , A61L31/16 , A61L2300/404 , A61L2300/416 , A61L2300/432
摘要： Compositions comprising anti-fibrotic agent(s) and/or polymeric compositions can be used in various medical applications including the prevention of surgical adhesions, treatment of inflammatory arthritis, treatment of scars and keloids, the treatment of vascular disease, and the prevention of cartilage loss.
摘要翻译： 包含抗纤维化剂和/或聚合物组合物的组合物可用于各种医学应用，包括预防手术粘连，治疗炎性关节炎，治疗瘢痕和瘢痕疙瘩，治疗血管疾病和预防软骨 失利。
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公开(公告)号：US20050178396A1
公开(公告)日：2005-08-18
申请号：US11006905
申请日：2004-12-07
申请人： William Hunter , Philip Toleikis , David Gravett , Arpita Maiti , Richard Liggins , Aniko Takacs-Cox , Rui Avelar , Troy Loss
发明人： William Hunter , Philip Toleikis , David Gravett , Arpita Maiti , Richard Liggins , Aniko Takacs-Cox , Rui Avelar , Troy Loss
IPC分类号： A61B19/00 , A61F2/00 , A61F2/08 , A61F2/28 , A61F2/44 , A61K9/14 , A61K31/337 , A61K31/365 , A61K31/4745 , A61K31/704 , A61K31/7048 , A61K31/7072 , A61K38/00 , A61L27/54 , A61L31/16 , A61M31/00 , A61N1/00 , A61N1/05
CPC分类号： A61K45/06 , A61L27/54 , A61L31/16 , A61L2300/404 , A61L2300/416 , A61L2300/432
摘要： Compositions comprising anti-fibrotic agent(s) and/or polymeric compositions can be used in various medical applications including the prevention of surgical adhesions, treatment of inflammatory arthritis, treatment of scars and keloids, the treatment of vascular disease, and the prevention of cartilage loss.
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公开(公告)号：US20050178395A1
公开(公告)日：2005-08-18
申请号：US11006900
申请日：2004-12-07
申请人： William Hunter , Philip Toleikis , David Gravett , Arpita Maiti , Richard Liggins , Aniko Takacs-Cox , Rui Avelar , Troy Loss
发明人： William Hunter , Philip Toleikis , David Gravett , Arpita Maiti , Richard Liggins , Aniko Takacs-Cox , Rui Avelar , Troy Loss
IPC分类号： A61B19/00 , A61F2/00 , A61F2/08 , A61F2/28 , A61F2/44 , A61K9/14 , A61K31/337 , A61K31/365 , A61K31/4745 , A61K31/704 , A61K31/7048 , A61K31/7072 , A61K38/00 , A61L27/54 , A61L31/16 , A61M31/00 , A61N1/00 , A61N1/05
CPC分类号： A61K45/06 , A61L27/54 , A61L31/16 , A61L2300/404 , A61L2300/416 , A61L2300/432
摘要： Compositions comprising anti-fibrotic agent(s) and/or polymeric compositions can be used in various medical applications including the prevention of surgical adhesions, treatment of inflammatory arthritis, treatment of scars and keloids, the treatment of vascular disease, and the prevention of cartilage loss.
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公开(公告)号：US20070270447A1
公开(公告)日：2007-11-22
申请号：US11888511
申请日：2007-07-31
申请人： William Hunter , David Gravett , Philip Toleikis , Richard Liggins , Troy Loss
发明人： William Hunter , David Gravett , Philip Toleikis , Richard Liggins , Troy Loss
IPC分类号： A61K31/513 , A61P31/00
CPC分类号： A61L29/16 , A61L27/34 , A61L27/54 , A61L29/085 , A61L2300/404 , A61L2300/416
摘要： Medical implants are provided which release an anthracycline, fluoropyrimidine, folic acid antagonist, podophylotoxin, camptothecin, hydroxyurea, and/or platinum complex, thereby inhibiting or reducing the incidence of infection associated with the implant.
摘要翻译： 提供了释放蒽环类抗生素，氟嘧啶，叶酸拮抗剂，足细胞毒素，喜树碱，羟基脲和/或铂络合物的医学植入物，从而抑制或降低与植入相关的感染的发生率。
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公开(公告)号：US20080089952A1
公开(公告)日：2008-04-17
申请号：US11888674
申请日：2007-07-31
申请人： William Hunter , David Gravett , Philip Toleikis , Richard Liggins , Troy Loss
发明人： William Hunter , David Gravett , Philip Toleikis , Richard Liggins , Troy Loss
CPC分类号： A61L29/16 , A61L27/34 , A61L27/54 , A61L29/085 , A61L2300/404 , A61L2300/416
摘要： Medical implants are provided which release an anthracycline, fluoropyrimidine, folic acid antagonist, podophylotoxin, camptothecin, hydroxyurea, and/or platinum complex, thereby inhibiting or reducing the incidence of infection associated with the implant.
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