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    Method and apparatus for detecting cardiac capture
    3.
    发明授权
    Method and apparatus for detecting cardiac capture 失效
    用于检测心脏捕获的方法和装置

    公开(公告)号：US5902325A

    公开(公告)日：1999-05-11

    申请号：US126469

    申请日：1998-07-30

    申请人： Catherine R. Condie ,  Daniel J. Baxter ,  William J. Combs ,  Daniel J. Greeninger ,  Karen J. Kleckner ,  H. Toby Markowitz ,  John C. Stroebel ,  John D. Wahlstrand

    发明人： Catherine R. Condie ,  Daniel J. Baxter ,  William J. Combs ,  Daniel J. Greeninger ,  Karen J. Kleckner ,  H. Toby Markowitz ,  John C. Stroebel ,  John D. Wahlstrand

    IPC分类号： A61N1/365 ,  A61N1/37

    CPC分类号： A61N1/36521 ,  A61N1/3712 ,  A61N1/3714

    摘要： A method and apparatus for automatic determination of a pacemaker patient's pacing stimulation threshold. Circuitry is provided in a pacemaker for obtaining a signal reflecting cardiac impedance, which is known to reliably reflect certain aspects of cardiac function. Circuitry is also provided for monitoring the cardiac impedance waveform during a predetermined capture detect window following delivery of stimulating pulses. One or more values are derived which characterize the morphology of the impedance waveform during the capture detect window associated with each stimulation pulse delivered. These values are compared to predetermined control values in order to assess whether a stimulation pulse has achieved cardiac capture. The assessment of whether cardiac capture has been achieved is also based partly upon the conventional sensing of atrial and/or ventricular cardiac signals occurring during the capture detect window. In one embodiment of the invention, the control values against which impedance waveform characterization values are compared are obtained by delivering a series of stimulation pulses having sufficient energy to ensure that capture is achieved, and by monitoring the impedance waveform during delivery of these pulses.

    摘要翻译： 一种用于自动确定起搏器患者起搏刺激阈值的方法和装置。 在起搏器中提供电路以获得反映心脏阻抗的信号，这已知可靠地反映心脏功能的某些方面。 还提供电路用于在传送刺激脉冲之后的预定捕获检测窗口期间监测心脏阻抗波形。 导出一个或多个值，其表征在与递送的每个刺激脉冲相关联的捕获检测窗口期间阻抗波形的形态。 将这些值与预定的控制值进行比较，以便评估刺激脉冲是否已经实现心脏捕获。 是否已经实现心脏捕获的评估也部分地基于在捕获检测窗口期间发生的心房和/或心室心脏信号的常规感测。 在本发明的一个实施例中，通过递送具有足够能量的一系列刺激脉冲来确定阻抗波形表征值被比较的控制值，以确保实现捕获，并且通过在传送这些脉冲期间监视阻抗波形来获得。

    Capture detection method
    4.
    发明授权
    Capture detection method 失效
    捕获检测方法

    公开(公告)号：US5843137A

    公开(公告)日：1998-12-01

    申请号：US784687

    申请日：1997-01-22

    申请人： Catherine R. Condie ,  Daniel J. Baxter ,  William J. Combs ,  Daniel J. Greeninger ,  Karen J. Kleckner ,  H. Toby Markowitz ,  John C. Stroebel ,  John D. Wahlstrand

    发明人： Catherine R. Condie ,  Daniel J. Baxter ,  William J. Combs ,  Daniel J. Greeninger ,  Karen J. Kleckner ,  H. Toby Markowitz ,  John C. Stroebel ,  John D. Wahlstrand

    IPC分类号： A61N1/365 ,  A61N1/37

    CPC分类号： A61N1/36521 ,  A61N1/3712 ,  A61N1/3714

    摘要： A method and apparatus for automatic determination of a pacemaker patient's pacing stimulation threshold. Circuitry is provided in a pacemaker for obtaining a signal reflecting cardiac impedance, which is known to reliably reflect certain aspects of cardiac function. Circuitry is also provided for monitoring the cardiac impedance waveform during a predetermined capture detect window following delivery of stimulating pulses. One or more values are derived which characterize the morphology of the impedance waveform during the capture detect window associated with each stimulation pulse delivered. These values are compared to predetermined control values in order to assess whether a stimulation pulse has achieved cardiac capture. The assessment of whether cardiac capture has been achieved is also based partly upon the conventional sensing of atrial and/or ventricular cardiac signals occurring during the capture detect window. In one embodiment of the invention, the control values against which impedance waveform characterization values are compared are obtained by delivering a series of stimulation pulses having sufficient energy to ensure that capture is achieved, and by monitoring the impedance waveform during delivery of these pulses.

    摘要翻译： 一种用于自动确定起搏器患者起搏刺激阈值的方法和装置。 在起搏器中提供电路以获得反映心脏阻抗的信号，这已知可靠地反映心脏功能的某些方面。 还提供电路用于在传送刺激脉冲之后的预定捕获检测窗口期间监测心脏阻抗波形。 导出一个或多个值，其表征在与递送的每个刺激脉冲相关联的捕获检测窗口期间阻抗波形的形态。 将这些值与预定的控制值进行比较，以便评估刺激脉冲是否已经实现心脏捕获。 是否已经实现心脏捕获的评估也部分地基于在捕获检测窗口期间发生的心房和/或心室心脏信号的常规感测。 在本发明的一个实施例中，通过递送具有足够能量的一系列刺激脉冲来确定阻抗波形表征值被比较的控制值，以确保实现捕获，并且通过在传送这些脉冲期间监视阻抗波形来获得。

    Method and apparatus for automatic pacing threshold determination
    5.
    发明授权
    Method and apparatus for automatic pacing threshold determination 失效
    用于自动起搏阈值确定的方法和装置

    公开(公告)号：US5713933A

    公开(公告)日：1998-02-03

    申请号：US346815

    申请日：1994-11-30

    申请人： Catherine R. Condie ,  Daniel J. Baxter ,  William J. Combs ,  Daniel J. Greeninger ,  Karen J. Kleckner ,  H. Toby Markowitz ,  John C. Stroebel ,  John D. Wahlstrand

    发明人： Catherine R. Condie ,  Daniel J. Baxter ,  William J. Combs ,  Daniel J. Greeninger ,  Karen J. Kleckner ,  H. Toby Markowitz ,  John C. Stroebel ,  John D. Wahlstrand

    IPC分类号： A61N1/365 ,  A61N1/37

    CPC分类号： A61N1/36521 ,  A61N1/3712 ,  A61N1/3714

    摘要： A method and apparatus for automatic determination of a pacemaker patient's pacing stimulation threshold. Circuitry is provided in a pacemaker for obtaining a signal reflecting cardiac impedance, which is known to reliably reflect certain aspects of cardiac function. Circuitry is also provided for monitoring the cardiac impedance waveform during a predetermined capture detect window following delivery of stimulating pulses. One or more values are derived which characterize the morphology of the impedance waveform during the capture detect window associated with each stimulation pulse delivered. These values are compared to predetermined control values in order to assess whether a stimulation pulse has achieved cardiac capture. The assessment of whether cardiac capture has been achieved is also based partly upon the conventional sensing of atrial and/or ventricular cardiac signals occurring during the capture detect window. In one embodiment of the invention, the control values against which impedance waveform characterization values are compared are obtained by delivering a series of stimulation pulses having sufficient energy to ensure that capture is achieved, and by monitoring the impedance waveform during delivery of these pulses.

    摘要翻译： 一种用于自动确定起搏器患者起搏刺激阈值的方法和装置。 在起搏器中提供电路以获得反映心脏阻抗的信号，这已知可靠地反映心脏功能的某些方面。 还提供电路用于在传送刺激脉冲之后的预定捕获检测窗口期间监测心脏阻抗波形。 导出一个或多个值，其表征在与递送的每个刺激脉冲相关联的捕获检测窗口期间阻抗波形的形态。 将这些值与预定的控制值进行比较，以便评估刺激脉冲是否已经实现心脏捕获。 是否已经实现心脏捕获的评估也部分地基于在捕获检测窗口期间发生的心房和/或心室心脏信号的常规感测。 在本发明的一个实施例中，通过递送具有足够能量的一系列刺激脉冲来确定阻抗波形表征值被比较的控制值，以确保实现捕获，并且通过在传送这些脉冲期间监视阻抗波形来获得。

    System and method of using AV conduction timing
    6.
    发明授权
    System and method of using AV conduction timing 有权
    使用AV导通定时的系统和方法

    公开(公告)号：US08229560B2

    公开(公告)日：2012-07-24

    申请号：US13078536

    申请日：2011-04-01

    申请人： Catherine R. Condie

    发明人： Catherine R. Condie

    IPC分类号： A61N1/362

    CPC分类号： A61N1/368 ,  A61B5/0468 ,  A61N1/3682

    摘要： In an implantable medical device that provides atrial and ventricular pacing in an atrial-based pacing mode, longer periods of time are permitted for intrinsic AV conduction to occur. By monitoring the patient's AV delay under these circumstances, useful information is obtained that can be correlated to other patient conditions or symptoms.

    摘要翻译： 在以心房起搏模式提供心房和心室起搏的植入式医疗装置中，允许发生固有AV传导的较长时间段。 通过在这些情况下监测患者的AV延迟，获得可以与其他患者状况或症状相关的有用信息。

    Multipolarity epicardial radiofrequency ablation
    10.
    发明授权
    Multipolarity epicardial radiofrequency ablation 有权
    多极性心外膜射频消融

    公开(公告)号：US09044245B2

    公开(公告)日：2015-06-02

    申请号：US12984675

    申请日：2011-01-05

    申请人： Catherine R. Condie ,  Sarah E. Ahlberg

    发明人： Catherine R. Condie ,  Sarah E. Ahlberg

    IPC分类号： A61B18/18 ,  A61B18/14 ,  A61B18/00

    CPC分类号： A61B18/1492 ,  A61B2018/00029 ,  A61B2018/00267 ,  A61B2018/00363 ,  A61B2018/00577 ,  A61B2018/00821 ,  A61B2018/1407 ,  A61B2018/1467 ,  A61B2218/002

    摘要： A method of ablating an epicardial tissue region, including positioning a medical device adjacent the epicardial tissue region, the medical device having a first electrode, a second electrode, and a third electrode located in between the first and second electrodes; delivering an irrigation fluid to the tissue region; and ablating at least a portion of the tissue region by sequentially activating the third electrode in a monopolar radiofrequency delivery mode and activating the first and second electrodes in a bipolar radiofrequency delivery mode.

    摘要翻译： 一种消融心外膜组织区域的方法，包括定位邻近心外膜组织区域的医疗装置，所述医疗装置具有位于第一和第二电极之间的第一电极，第二电极和第三电极; 向组织区域输送冲洗流体; 以及通过以单极射频递送模式顺序启动所述第三电极并且以双极射频递送模式激活所述第一和第二电极，从而消融所述组织区域的至少一部分。