公开(公告)号：US11504437B2

公开(公告)日：2022-11-22

申请号：US15706429

申请日：2017-09-15

申请人： William Marsh Rice University

发明人： Nancy J. Halas ,  Ciceron Ayala-Orozco ,  Sandra Bishnoi ,  Luke Henderson ,  Oara Neumann ,  Robia Pautler ,  Peter Nordlander

IPC分类号： A61K49/18 ,  H01B3/02 ,  C23C18/16 ,  C23C18/31

摘要： A Magnetic Resonance Imaging (MRI) enhancement agent includes a plurality of particles, each particle including: a metal core; a dielectric shell disposed on the metal core comprising at least one MRI contrast agent; and a metal shell disposed on the exterior surface of the dielectric shell that encapsulates the dielectric shell.

公开(公告)号：US20180008730A1

公开(公告)日：2018-01-11

申请号：US15706429

申请日：2017-09-15

申请人： William Marsh Rice University

发明人： Nancy J. Halas ,  Ciceron Ayala-Orozco ,  Sandra Bishnoi ,  Luke Henderson ,  Oara Neumann ,  Robia Pautler

IPC分类号： A61K49/18 ,  C23C18/16 ,  C23C18/31 ,  H01B3/02

CPC分类号： A61K49/1881 ,  A61K49/1833 ,  C23C18/1646 ,  C23C18/31 ,  H01B3/02

摘要： A Magnetic Resonance Imaging (MRI) enhancement agent includes a plurality of particles, each particle including: a metal core; a dielectric shell disposed on the metal core comprising at least one MRI contrast agent; and a metal shell disposed on the exterior surface of the dielectric shell that encapsulates the dielectric shell.