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公开(公告)号:US20120107306A1
公开(公告)日:2012-05-03
申请号:US13214413
申请日:2011-08-22
申请人: Winfried ELIS , Seth ETTENGERG , Andrew Paul GARNER , Nicole HAUBST , Christian Carsten Silvester KUNZ , Elizabeth Anne Reisinger SPRAGUE
发明人: Winfried ELIS , Seth ETTENGERG , Andrew Paul GARNER , Nicole HAUBST , Christian Carsten Silvester KUNZ , Elizabeth Anne Reisinger SPRAGUE
IPC分类号: A61K39/395 , A61P35/00 , A61P35/02 , C07K16/40
CPC分类号: C07K16/32 , A61K39/39558 , A61K45/06 , A61K2039/505 , C07K16/30 , C07K16/3015 , C07K16/3023 , C07K16/303 , C07K16/3038 , C07K16/3046 , C07K16/3053 , C07K16/3061 , C07K16/3069 , C07K2317/21 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/522 , C07K2317/524 , C07K2317/526 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/73 , C07K2317/76 , C07K2317/92 , A61K2300/00
摘要: The present invention relates to antibodies or fragments thereof that target a conformational epitope of a HER receptor. In particular, the invention relates to antibodies or fragments thereof that target a conformational epitope of HER3 receptor and compositions and methods of use thereof.
摘要翻译: 本发明涉及靶向HER受体的构象表位的抗体或其片段。 特别地,本发明涉及靶向HER3受体的构象表位的抗体或其片段,以及组合物及其使用方法。
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公开(公告)号:US20170166653A1
公开(公告)日:2017-06-15
申请号:US14280017
申请日:2014-05-16
申请人: Andrew Paul GARNER , Elizabeth Anne Reisinger SPRAGUE , Seth Alexander ETTENBERG , Christian KUNZ , Nicole HAUBST , Winfried ELIS
发明人: Andrew Paul GARNER , Elizabeth Anne Reisinger SPRAGUE , Seth Alexander ETTENBERG , Christian KUNZ , Nicole HAUBST , Winfried ELIS
IPC分类号: C07K16/32 , A61K39/395 , A61K45/06 , C07K16/30
CPC分类号: C07K16/32 , A61K39/39558 , A61K45/06 , A61K2039/505 , C07K16/30 , C07K16/3015 , C07K16/3023 , C07K16/303 , C07K16/3038 , C07K16/3046 , C07K16/3053 , C07K16/3061 , C07K16/3069 , C07K2317/21 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/522 , C07K2317/524 , C07K2317/526 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/73 , C07K2317/76 , C07K2317/92 , A61K2300/00
摘要: The present invention relates to antibodies or fragments thereof that target a conformational epitope of a HER receptor. In particular, the invention relates to antibodies or fragments thereof that target a conformational epitope of HER3 receptor and compositions and methods of use thereof.
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3.THYMIC STROMAL LYMPHOPOIETIN (TSLP)-BINDING MOLECULES AND METHODS OF USING THE MOLECULES 有权
标题翻译: THYMIC STROMAL LYMPHOPOIETIN(TSLP) - 使用分子的分子和方法公开(公告)号:US20170066823A1
公开(公告)日:2017-03-09
申请号:US15258683
申请日:2016-09-07
申请人: Matthew John EDWARDS , Jean-Michel Rene RONDEAU , Danforth Miller , Daniel Huang , Hans-Peter KNOPF , Gino Anselmus VAN HEEKE , Rene HEMMIG , Kapil GUPTA , Nicole HAUBST , Barbara ANDLAUER
发明人: Matthew John EDWARDS , Jean-Michel Rene RONDEAU , Danforth Miller , Daniel Huang , Hans-Peter KNOPF , Gino Anselmus VAN HEEKE , Rene HEMMIG , Kapil GUPTA , Nicole HAUBST , Barbara ANDLAUER
IPC分类号: C07K16/24 , A61K47/42 , A61K45/06 , A61K9/00 , A61K47/26 , A61K47/22 , A61K39/395 , A61K47/18
CPC分类号: C07K16/24 , A61K9/0043 , A61K9/0075 , A61K9/1617 , A61K9/1623 , A61K39/3955 , A61K45/06 , A61K2039/505 , A61K2039/544 , A61K2039/545 , C07K16/244 , C07K2317/21 , C07K2317/33 , C07K2317/34 , C07K2317/55 , C07K2317/76 , C07K2317/92 , C07K2317/94
摘要: The invention provides molecules, e.g., antibodies or antibody fragments, that specifically bind thymic stromal lymphopoietin (TSLP), compositions comprising these molecules, and methods of using and producing these molecules.
摘要翻译: 本发明提供特异性结合胸腺基质淋巴细胞生成素(TSLP),包含这些分子的组合物的分子,例如抗体或抗体片段,以及使用和产生这些分子的方法。
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