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公开(公告)号:US10280405B2
公开(公告)日:2019-05-07
申请号:US15913058
申请日:2018-03-06
IPC分类号: A61K38/00 , A61K38/17 , A61K39/125 , C07K14/00 , C07K14/005 , C12N7/00 , C07K14/705 , G01N33/50
摘要: The present invention provides methods of propagating rhinovirus C (RV-C) in a host cell; a host cell comprising an effective amount of a heterologous CDHR3 receptor such that the host cell can support propagation of rhinovirus C; and kits comprising at least one host cell previously unable to support rhinovirus C growth, wherein the host cell comprises a heterologous CDHR3 receptor and a sample of rhinovirus C. Methods of use are also provided.
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公开(公告)号:US20170082609A1
公开(公告)日:2017-03-23
申请号:US14836327
申请日:2015-08-26
CPC分类号: C12N7/00 , C07K14/705 , C12N2770/32751 , G01N33/5014 , G01N2333/095 , G01N2500/10
摘要: The present invention provides methods of propagating rhinovirus C (RV-C) in a host cell; a host cell comprising an effective amount of a heterologous CDHR3 receptor such that the host cell can support propagation of rhinovirus C; and kits comprising at least one host cell previously unable to support rhinovirus C growth, wherein the host cell comprises a heterologous CDHR3 receptor and a sample of rhinovirus C. Methods of use are also provided.
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公开(公告)号:US20170044503A1
公开(公告)日:2017-02-16
申请号:US15232913
申请日:2016-08-10
IPC分类号: C12N7/00
CPC分类号: C12N7/00 , C07K14/005 , C12N2770/32721 , C12N2770/32722
摘要: A mutated rhinovirus C, methods of creating and methods of propagating thereof, wherein the mutated rhinovirus shows enhanced virus yields after infection and induced visible cytopathic effect.
摘要翻译: 突变的鼻病毒C,其产生方法和繁殖方法,其中突变的鼻病毒在感染后显示出增强的病毒产量并诱导可见的细胞病变效应。
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公开(公告)号:US10253300B2
公开(公告)日:2019-04-09
申请号:US15232913
申请日:2016-08-10
IPC分类号: C07K14/005 , C12N7/00 , A61K39/125
摘要: A mutated rhinovirus C, methods of creating and methods of propagating thereof, wherein the mutated rhinovirus shows enhanced virus yields after infection and induced visible cytopathic effect.
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公开(公告)号:US20170305973A1
公开(公告)日:2017-10-26
申请号:US15491513
申请日:2017-04-19
发明人: Ann C. Palmenberg , Marchel Goldsby Hill , Kelly Elizabeth Watters , Michael G. Rossman , Yue Liu
IPC分类号: C07K14/005 , C12N7/00 , A61K39/125 , C07K16/10
CPC分类号: C07K14/005 , A61K39/12 , A61K39/125 , A61K2039/5254 , A61K2039/5258 , C07K16/1009 , C07K2317/34 , C07K2317/76 , C12N7/00 , C12N2770/32722 , C12N2770/32723 , C12N2770/32734
摘要: A peptide comprising the rhinovirus immunogen peptide of the rhinovirus structural protein 1 (VP1) of rhinovirus C and related vaccines and therapeutic compositions is disclosed.
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公开(公告)号:US10428116B2
公开(公告)日:2019-10-01
申请号:US15491513
申请日:2017-04-19
发明人: Ann C. Palmenberg , Marchel Goldsby Hill , Kelly Elizabeth Watters , Michael G. Rossman , Yue Liu
IPC分类号: C07K14/005 , A61K39/125 , C12N7/00 , C07K16/10
摘要: A peptide comprising the rhinovirus immunogen peptide of the rhinovirus structural protein 1 (VP1) of rhinovirus C and related vaccines and therapeutic compositions is disclosed.
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公开(公告)号:US20190055521A1
公开(公告)日:2019-02-21
申请号:US15913058
申请日:2018-03-06
IPC分类号: C12N7/00 , C07K14/705 , G01N33/50
摘要: The present invention provides methods of propagating rhinovirus C (RV-C) in a host cell; a host cell comprising an effective amount of a heterologous CDHR3 receptor such that the host cell can support propagation of rhinovirus C; and kits comprising at least one host cell previously unable to support rhinovirus C growth, wherein the host cell comprises a heterologous CDHR3 receptor and a sample of rhinovirus C. Methods of use are also provided.
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公开(公告)号:US09938507B2
公开(公告)日:2018-04-10
申请号:US14836327
申请日:2015-08-26
IPC分类号: C12N7/00 , G01N33/50 , A61K39/125 , C07K14/005 , C07K16/10
CPC分类号: C12N7/00 , C07K14/705 , C12N2770/32751 , G01N33/5014 , G01N2333/095 , G01N2500/10
摘要: The present invention provides methods of propagating rhinovirus C (RV-C) in a host cell; a host cell comprising an effective amount of a heterologous CDHR3 receptor such that the host cell can support propagation of rhinovirus C; and kits comprising at least one host cell previously unable to support rhinovirus C growth, wherein the host cell comprises a heterologous CDHR3 receptor and a sample of rhinovirus C. Methods of use are also provided.
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