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公开(公告)号：US20160022804A1
公开(公告)日：2016-01-28
申请号：US14774924
申请日：2014-03-15
发明人： Gregory J Tobin , Peter L Nara
IPC分类号： A61K39/125 , C07K14/005
CPC分类号： A61K39/125 , A61K39/12 , A61K2039/5258 , A61K2039/58 , C07K14/005 , C07K14/095 , C07K16/1009 , C07K2317/33 , C07K2317/76 , C07K2319/00 , C12N2770/32722 , C12N2770/32723 , C12N2770/32734 , Y02A50/396
摘要： Novel compositions useful as human rhino virus immunogens are provided. The compositions enable a host response to sites normally not recognized by a host.
摘要翻译： 提供了可用作人犀牛病毒免疫原的新型组合物。 该组合物使主机能够对通常不被主机识别的位置进行响应。
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公开(公告)号：US09872899B2
公开(公告)日：2018-01-23
申请号：US14774924
申请日：2014-03-15
发明人： Gregory J Tobin , Peter L Nara
IPC分类号： A61K39/12 , A61K39/125 , C07K14/095 , C07K14/005 , C07K16/10 , A61K39/00
CPC分类号： A61K39/125 , A61K39/12 , A61K2039/5258 , A61K2039/58 , C07K14/005 , C07K14/095 , C07K16/1009 , C07K2317/33 , C07K2317/76 , C07K2319/00 , C12N2770/32722 , C12N2770/32723 , C12N2770/32734 , Y02A50/396
摘要： Novel compositions useful as human rhinovirus immunogens are provided. The compositions enable a host response to sites normally not recognized by a host.
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公开(公告)号：US20170305973A1
公开(公告)日：2017-10-26
申请号：US15491513
申请日：2017-04-19
发明人： Ann C. Palmenberg , Marchel Goldsby Hill , Kelly Elizabeth Watters , Michael G. Rossman , Yue Liu
IPC分类号： C07K14/005 , C12N7/00 , A61K39/125 , C07K16/10
CPC分类号： C07K14/005 , A61K39/12 , A61K39/125 , A61K2039/5254 , A61K2039/5258 , C07K16/1009 , C07K2317/34 , C07K2317/76 , C12N7/00 , C12N2770/32722 , C12N2770/32723 , C12N2770/32734
摘要： A peptide comprising the rhinovirus immunogen peptide of the rhinovirus structural protein 1 (VP1) of rhinovirus C and related vaccines and therapeutic compositions is disclosed.
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4.发明公开公开(公告)号：US20240350615A1
公开(公告)日：2024-10-24
申请号：US18292538
申请日：2022-07-21
发明人： Tong CHENG , Rui ZHU , Hongwei YANG , Longfa XU , Yu LIN , Zhenhong ZHOU , Xiangzhong YE , Ningshao XIA
IPC分类号： A61K39/125 , A61K39/00 , A61K39/385 , A61P31/16 , C07K14/005 , C07K16/10 , G01N33/569 , G01N33/68
CPC分类号： A61K39/125 , A61K39/385 , A61P31/16 , C07K14/005 , C07K16/1009 , G01N33/56983 , G01N33/6854 , A61K2039/6075 , C07K2317/14 , C07K2317/24 , C07K2317/565 , C07K2317/76 , C12N2770/32722 , C12N2770/32723 , G01N2333/095
摘要： The present invention belongs to the field of immunobiology, and relates to an epitope polypeptide, such as a general affinity epitope polypeptide of human rhinovirus, and the use thereof. The present invention further relates to an antibody capable of binding to the epitope polypeptide and the use thereof. The present invention further relates to the use of the affinity epitope polypeptide or the antibody in the preparation of drugs or in methods for treating and/or preventing and/or diagnosing human rhinovirus and/or identifying a titer of human rhinovirus and/or identifying a titer of a neutralizing antibody of human rhinovirus. The affinity epitope polypeptide and antibody can be used in drugs or methods for treating and/or preventing and/or diagnosing human rhinovirus and/or identifying a titer of human rhinovirus and/or identifying a titer of a neutralizing antibody of human rhinovirus.
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公开(公告)号：US20180064802A1
公开(公告)日：2018-03-08
申请号：US15811744
申请日：2017-11-14
发明人： Gregory J Tobin , Peter L Nara
IPC分类号： A61K39/125 , C07K16/10 , A61K39/12 , C07K14/005 , C07K14/095 , A61K39/00
CPC分类号： A61K39/125 , A61K39/12 , A61K2039/5258 , A61K2039/58 , C07K14/005 , C07K14/095 , C07K16/1009 , C07K2317/33 , C07K2317/34 , C07K2317/76 , C07K2319/00 , C12N2770/32034 , C12N2770/32722 , C12N2770/32723 , C12N2770/32734
摘要： Novel compositions useful as human rhino virus immunogens are provided. The compositions enable a host response to sites normally not recognized by a host.
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