公开(公告)号：US09128059B2

公开(公告)日：2015-09-08

申请号：US13257194

申请日：2010-03-19

Applicant: Wolfgang Langbein ,  Paola Borri

Inventor： Wolfgang Langbein ,  Paola Borri

IPC: G01J3/44 ,  G01J3/30 ,  G01N21/25 ,  G01J1/58 ,  G01N21/64 ,  G01N21/65 ,  G01J3/02

CPC classification number: G01N21/65 ,  G01J3/02 ,  G01J3/0224 ,  G01J3/44 ,  G01N2021/653

Abstract: A coherent anti-Stokes Raman spectroscopy (CARS) system comprises a laser light source for emitting pulsed light, a dichroic beam splitter for splitting a light pulse from the light source into a pump pulse and a Stokes pulse and directing these pulses along respective distinct paths, chirping means, e.g. dispersive glass blocks for chirping the pump and Stokes pulses, directing means for directing the chirped pump and Stokes samples to a sample in time overlap, and detecting means for detecting light stimulated from the sample by the interaction of the pump and Stokes pulses. The system may comprise a reflector connected to a linear motor, for adjusting the period between the arrival at the sample of the starts of the chirped pump and Stokes pulses. The system may further comprise a pulse replicating unit for converting a pulse from the light source into a plurality of pulses distributed in time.

Abstract translation: 相干的反斯托克斯拉曼光谱（CARS）系统包括用于发射脉冲光的激光光源，用于将来自光源的光脉冲分解为泵脉冲和斯托克斯脉冲的二向色分束器，并将这些脉冲引导到相应的不同路径 啁啾手段，例如 用于啁啾泵和斯托克斯脉冲的分散玻璃块，用于将啁啾的泵和斯托克斯样品以时间重叠的方式引导到样品的引导装置，以及用于通过泵和斯托克斯脉冲的相互作用检测从样品刺激的光的检测装置。 系统可以包括连接到线性电动机的反射器，用于调节到达啁啾泵的起始点与斯托克斯脉冲之间的时间段。 该系统还可以包括用于将来自光源的脉冲转换成在时间上分布的多个脉冲的脉冲复制单元。

公开(公告)号：US08817261B2

公开(公告)日：2014-08-26

申请号：US13140163

申请日：2009-12-15

Applicant: Paola Borri ,  Wolfgang Langbein ,  Francesco Masia

Inventor： Paola Borri ,  Wolfgang Langbein ,  Francesco Masia

IPC: G01N21/55

CPC classification number: G01N33/54373 ,  B82Y20/00 ,  G01B11/2441 ,  G01N21/554 ,  G02B5/008 ,  G02B21/00 ,  G02F1/33 ,  G02F1/3526 ,  G02F1/3536 ,  G02F2202/36 ,  G02F2203/10

Abstract: Laser pulses are applied to surface plasmon resonant articles such as gold nanoparticles within a microscopy sample to generate a four-wave mixing signal that is detected as the output of the microscopy process.

Abstract translation: 将激光脉冲施加到表面等离子体共振制品例如显微镜样品中的金纳米颗粒以产生被检测为显微镜方法的输出的四波混合信号。

公开(公告)号：US20120092662A1

公开(公告)日：2012-04-19

申请号：US13257194

申请日：2010-03-19

Applicant: Wolfgang Langbein ,  Paola Borri

Inventor： Wolfgang Langbein ,  Paola Borri

IPC: G01J3/44

CPC classification number: G01N21/65 ,  G01J3/02 ,  G01J3/0224 ,  G01J3/44 ,  G01N2021/653

Abstract: A coherent anti-Stokes Raman spectroscopy (CARS) system comprises a laser light source for emitting pulsed light, a dichroic beam splitter for splitting a light pulse from the light source into a pump pulse and a Stokes pulse and directing these pulses along respective distinct paths, chirping means, e.g. dispersive glass blocks for chirping the pump and Stokes pulses, directing means for directing the chirped pump and Stokes samples to a sample in time overlap, and detecting means for detecting light stimulated from the sample by the interaction of the pump and Stokes pulses. The system may comprise a reflector connected to a linear motor, for adjusting the period between the arrival at the sample of the starts of the chirped pump and Stokes pulses. The system may further comprise a pulse replicating unit for converting a pulse from the light source into a plurality of pulses distributed in time.

Abstract translation: 相干的反斯托克斯拉曼光谱（CARS）系统包括用于发射脉冲光的激光光源，用于将来自光源的光脉冲分解为泵脉冲和斯托克斯脉冲的二向色分束器，并将这些脉冲引导到相应的不同路径 啁啾手段，例如 用于啁啾泵和斯托克斯脉冲的分散玻璃块，用于将啁啾的泵和斯托克斯样品以时间重叠的方式引导到样品的引导装置，以及用于通过泵和斯托克斯脉冲的相互作用检测从样品刺激的光的检测装置。 系统可以包括连接到线性电动机的反射器，用于调节到达啁啾泵的起始点与斯托克斯脉冲之间的时间段。 该系统还可以包括用于将来自光源的脉冲转换成在时间上分布的多个脉冲的脉冲复制单元。