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公开(公告)号:US20180105786A1
公开(公告)日:2018-04-19
申请号:US15112909
申请日:2016-07-06
Applicant: XYLECO, INC.
Inventor: Marshall Medoff , Thomas Craig Masterman , Robert Paradis , Aiichiro Yoshida , Karen Heinze
Abstract: According to various aspects and embodiments, a system and method for aerobic fermentation of an aqueous sugar solution is provided. The system includes a vessel, at least one air diffuser in fluid communication with an interior of the vessel, and at least one blower that is configured to deliver air to the at least one air diffuser.
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公开(公告)号:US10364412B2
公开(公告)日:2019-07-30
申请号:US15112909
申请日:2016-07-06
Applicant: XYLECO, INC.
Inventor: Marshall Medoff , Thomas Craig Masterman , Robert Paradis , Aiichiro Yoshida , Karen Heinze
Abstract: According to various aspects and embodiments, a system and method for aerobic fermentation of an aqueous sugar solution is provided. The system includes a vessel, at least one air diffuser in fluid communication with an interior of the vessel, and at least one blower that is configured to deliver air to the at least one air diffuser.
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公开(公告)号:US20190024068A1
公开(公告)日:2019-01-24
申请号:US16151690
申请日:2018-10-04
Applicant: XYLECO, INC.
Inventor: Marshall Medoff , Natasha Kreder , James J. Lynch , Sean Landry , Aiichiro Yoshida , Desiree Pangilinan , Thomas Craig Masterman
Abstract: The present invention relates to compositions comprising an aglycosylated polypeptide having cellobiase activity, and methods for producing and using the same.
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公开(公告)号:US10131894B2
公开(公告)日:2018-11-20
申请号:US14768126
申请日:2015-08-07
Applicant: XYLECO, INC.
Inventor: Marshall Medoff , Natasha Kreder , James J. Lynch , Sean Landry , Aiichiro Yoshida , Desiree Pangilinan , Thomas Craig Masterman
Abstract: The present invention relates to compositions comprising an aglycosylated polypeptide having cellobiase activity, and methods for producing and using the same.
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公开(公告)号:US09963727B2
公开(公告)日:2018-05-08
申请号:US14016481
申请日:2013-09-03
Applicant: Xyleco, Inc.
Inventor: Marshall Medoff , Thomas Craig Masterman , Jaewoong Moon , Aiichiro Yoshida
Abstract: The processes disclosed herein include saccharifying cellulosic and/or lignocellulosic biomass and fermenting the sugars to produce a sugar alcohol.
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公开(公告)号:US20170137797A1
公开(公告)日:2017-05-18
申请号:US14768126
申请日:2015-08-07
Applicant: XYLECO, INC.
Inventor: Marshall Medoff , Natasha Kreder , James Lynch , Sean Landry , Aiichiro Yoshida , Desiree Pangilinan , Thomas Craig Masterman
CPC classification number: C12N9/2445 , C12P19/02 , C12P19/14 , C12Y302/01021
Abstract: The present invention relates to compositions comprising an aglycosylated polypeptide having cellobiase activity, and methods for producing and using the same.
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公开(公告)号:US20190316108A1
公开(公告)日:2019-10-17
申请号:US16456536
申请日:2019-06-28
Applicant: XYLECO, INC.
Inventor: Marshall Medoff , Natasha Kreder , James Lynch , Sean Landry , Aiichiro Yoshida , Desiree Pangilinan , Thomas Craig Masterman
Abstract: The present invention relates to mixtures comprising a polypeptide or a plurality of polypeptides having biomass-degrading activity that is solubilized from an inclusion body, and retaining biomass-degrading activity, and methods for producing and using the same. The invention described herein provides methods for increasing the yield of recombinant protein with biomass-degrading activity that can be isolated from host cells.
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公开(公告)号:US20190292508A1
公开(公告)日:2019-09-26
申请号:US16439264
申请日:2019-06-12
Applicant: XYLECO, INC.
Inventor: Marshall Medoff , Thomas Craig Masterman , Robert Paradis , Aiichiro Yoshida , Karen Heinze
Abstract: A system for delivering air to an aqueous liquid for aerobic fermentation of the aqueous liquid includes a vessel having a length to diameter ratio of less than 2:1, an aeration system including at least one sparge tube having a pore size of less than 5 microns and a porosity of greater than 50 percent in fluid communication with an interior of the vessel, at least one blower configured to deliver air at a pressure of less than 15 psig to the at least one sparge tube, and a heat exchanger in fluid communication between the at least one blower and the at least one sparge tube that cools the air to below 100° F. (37.8° C.) prior to entering the at least one sparge tube.
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公开(公告)号:US10377999B2
公开(公告)日:2019-08-13
申请号:US14782205
申请日:2015-09-25
Applicant: XYLECO, INC.
Inventor: Marshall Medoff , Natasha Kreder , James J. Lynch , Sean Landry , Aiichiro Yoshida , Desiree Pangilinan , Thomas Craig Masterman
Abstract: The present invention relates to mixtures comprising a polypeptide or a plurality of polypeptides having biomass-degrading activity that is solubilized from an inclusion body, and retaining biomass-degrading activity, and methods for producing and using the same. The invention described herein provides methods for increasing the yield of recombinant protein with biomass-degrading activity that can be isolated from host cells.
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公开(公告)号:US20180010088A1
公开(公告)日:2018-01-11
申请号:US15031439
申请日:2016-03-30
Applicant: XYLECO, INC.
Inventor: Marshall Medoff , Thomas Craig Masterman , Aiichiro Yoshida , Jaewoong Moon , Christopher G. Bergeron , James J. Lynch
CPC classification number: C12N1/14 , C12N1/22 , C12N1/38 , C12N9/2437 , C12P19/02 , C12P19/14 , C12Y302/01004 , Y02E50/16 , Y02E50/17
Abstract: The present invention relates to compositions to induce production of proteins, e.g., enzymes, e.g., amylases or biomass degrading enzymes in a host cell, and methods for increasing the yield of the proteins, e.g., enzymes produced. Such compositions comprise a caramelized sugar product. The methods described herein can also be used to enhance processing of biomass materials, e.g., to produce sugar products.
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