公开(公告)号：US20240228521A1

公开(公告)日：2024-07-11

申请号：US18554795

申请日：2022-04-14

Applicant: YEDA RESEARCH AND DEVELOPMENT CO. LTD.

Inventor： David SPERANDIO ,  Helena SHOMAR MONNGES ,  Eugene J. EISENBERG ,  Arthur MACHLENKIN

IPC: C07F9/6561 ,  A61K31/675

CPC classification number: C07F9/6561 ,  A61K31/675

Abstract: Disclosed herein are 3, 4-didehydro- and 3′-deoxy-3, 4-didehydro-compounds, and pharmaceutical compositions thereof. The 3, 4-didehydro- and 3′-deoxy-3, 4-didehydro-compounds, and pharmaceutical compositions thereof may be used in methods of treating diseases including virus-induced diseases, cancer, autoimmune diseases, immune disorders, and bacterial-associated diseases or infections, or combinations thereof. Examples of viral-induced diseases include viral infections by RNA or DNA viruses, for example SARS-CoV-2, EBV, and BKV.