PROCESS FOR PREPARATION OF 2-METHYL-2'-PHENYLPROPIONIC ACID DERIVATIVES AND NOVEL INTERMEDIATE COMPOUNDS
    4.
    发明申请
    PROCESS FOR PREPARATION OF 2-METHYL-2'-PHENYLPROPIONIC ACID DERIVATIVES AND NOVEL INTERMEDIATE COMPOUNDS 有权
    2-甲基-2'-苯基丙酸衍生物和新型中间体化合物的制备方法

    公开(公告)号:US20130116439A1

    公开(公告)日:2013-05-09

    申请号:US13726932

    申请日:2012-12-26

    申请人: YUHAN CORPORATION

    IPC分类号: C07D401/04

    摘要: The present invention relates to a process for preparing 2-methyl-2′-phenylpropionic acid derivatives showing antihistamine activity in more simplified way, intermediate compounds and their preparation processes used therefore. According to the present invention, pharmaceutically useful 2-methyl-2′-phenylpropionic acid derivatives can be prepared with high yield and purity on industrial scale.

    摘要翻译: 本发明涉及以更简化的方式制备显示出抗组胺活性的2-甲基-2'-苯基丙酸衍生物的方法,因此中间体化合物及其制备方法。 根据本发明,可以以工业规模高产率和纯度制备药学上可用的2-甲基-2'-苯基丙酸衍生物。