公开(公告)号：US20050064484A1

公开(公告)日：2005-03-24

申请号：US10929796

申请日：2004-08-31

申请人： Yasuhiro Kasai ,  Takashi Sugimoto ,  Isamu Muto ,  Kanako Iwao ,  Aiko Kondo

发明人： Yasuhiro Kasai ,  Takashi Sugimoto ,  Isamu Muto ,  Kanako Iwao ,  Aiko Kondo

IPC分类号： C12N15/09 ,  C12N15/113 ,  C12Q1/68 ,  G01N33/48 ,  G01N33/50 ,  G06F17/50 ,  G06F19/16 ,  G06F19/26 ,  G06F19/00

CPC分类号： G16B45/00 ,  G16B15/00

摘要： A visual interface that allows a user to designate intuitively a two-dimensional sequence suitable for a target sequence for a functional nucleic acid is provided. Secondary structure data of a target mRNA is displayed on a screen, and various information such as characteristic sequences to be effectively influenced by the functional nucleic acid, binding sites for protein motifs, and UTRs are displayed on the secondary structure. A target site of the functional nucleic acid is designated by the user with a pointing device, and the intuitive determination of a most suitable sequence is supported by repeating the design of the functional nucleic acid.

摘要翻译： 提供允许用户直观地指定适用于功能性核酸的靶序列的二维序列的视觉界面。 靶mRNA的二级结构数据显示在屏幕上，并且在二级结构上显示各种信息，例如功能性核酸的有效影响的特征序列，蛋白质基序的结合位点和UTR。 功能性核酸的靶位点由用户用指示设备指定，并且通过重复功能性核酸的设计来支持最合适的序列的直观确定。

公开(公告)号：US20060281129A1

公开(公告)日：2006-12-14

申请号：US11506839

申请日：2006-08-21

申请人： Kanako Iwao ,  Motonao Nakao ,  Keiichi Sato ,  Toshiki Morita ,  Susumu Kuwabata

发明人： Kanako Iwao ,  Motonao Nakao ,  Keiichi Sato ,  Toshiki Morita ,  Susumu Kuwabata

IPC分类号： C12Q1/68 ,  G01N33/53 ,  C12M1/34

CPC分类号： G01N33/54353

摘要： A technique is provided that easily detects biopolymers such as a DNA or a protein by utilizing semiconductor nanoparticles having different excitation wavelengths and fluorescence due to differences in particle size. By binding the semiconductor nanoparticles with avidin (or biotin), detection of biopolymers labeled with biotin (or avidin) is enabled.