公开(公告)号：US20240074473A1

公开(公告)日：2024-03-07

申请号：US18387165

申请日：2023-11-06

Applicant: Yeda Research and Development Co. Ltd.

Inventor： Eldad TZAHOR ,  Ori PORAT-AVINOAM ,  Tamar Miriam Rose EIGLER-HIRSH

IPC: A23L13/40 ,  C12N5/077

CPC classification number: A23L13/45 ,  C12N5/0658 ,  C12N2500/14 ,  C12N2501/50 ,  C12N2501/727 ,  C12N2510/00

Abstract: A method of inducing multinucleated myotube formation is provided. The method comprising contacting myogenic precursor cells from a farmed animal with an Extracellular Regulated Signaling Kinase (ERK1/2) inhibitor and/or an upregulator of intracellular Ca 2+ and/or RXR/RAR agonists, enhancing fusion and myogenic maturation.