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1.发明授权Process for surface modifying substrates and modified substrates resulting therefrom 有权用于表面改性基材和由其得到的改性基材的方法公开(公告)号：US06893685B2
公开(公告)日：2005-05-17
申请号：US09939145
申请日：2001-08-24
申请人： Yongxing Qiu , Lynn Cook Winterton , John Martin Lally , Paul Pasic , Hans Griesser , Peter Kambouris , Peter Chabrecek
发明人： Yongxing Qiu , Lynn Cook Winterton , John Martin Lally , Paul Pasic , Hans Griesser , Peter Kambouris , Peter Chabrecek
CPC分类号： C08J7/16 , A61L27/34 , G02B1/043 , Y10T428/31511 , Y10T428/31663 , Y10T428/31667 , Y10T428/31909 , Y10T428/31928
摘要： The invention relates to a process for coating a material surface, comprising the steps of: (a) applying to the material surface a tie layer comprising a polyionic material; (b) covalently binding a bifunctional compound comprising an ethylenically unsaturated double b3nd to the tie layer; and (c) graft polymerizing a hydrophilic monomer onto the compound comprising the ethylenically unsaturated double bond. The coated articles that are obtainable by the process of the invention have desirable characteristics regarding adherences to the substrate, durability, hydrophilicity, wettability, biocompatibility and permeability and are thus useful for the manufacture of biomedical articles such as ophthalmic devices.
摘要翻译： 本发明涉及一种用于涂覆材料表面的方法，包括以下步骤：（a）向材料表面施加包含聚离子材料的粘结层; （b）将包含烯属不饱和双b 3 nd的双官能化合物共价结合到连接层上; 和（c）将亲水性单体接枝聚合到包含烯属不饱和双键的化合物上。 通过本发明的方法可获得的涂覆制品具有关于与基材的粘合性，耐久性，亲水性，润湿性，生物相容性和渗透性有关的所需特性，因此可用于制造生物医学制品如眼科装置。
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公开(公告)号：US06582754B1
公开(公告)日：2003-06-24
申请号：US09697861
申请日：2000-10-27
IPC分类号： B05D138
摘要： The invention relates to a process for coating a material surface, comprising the steps of: (a) covalently binding a compound comprising an ethylenically unsaturated double bond to the material surface; (b) polymerizing a monomer comprising a reactive or crosslinkable group on the surface and thereby providing a primary polymer coating comprising reactive or crosslinkable groups, (c) in case of a monomer comprising a reactive group in step (b) reacting the reactive groups of the primary coating with a further compound comprising an ethylenically unsaturated double bond and graft-polymerizing a hydrophilic monomer and optionally a co-monomer having a crosslinkable group onto the primary coating obtained according to step (b) and (d) in case of crosslinkable groups being present in step (b) or (c) initiating crosslinking of said groups. The coated articles that are obtainable by the process of the invention have desirable characteristics regarding adherence to the substrate, durability, hydrophilicity, wettability, biocompatibility and permeability and are thus useful for the manufacture of biomedical articles such as ophthalmic devices.
摘要翻译： 本发明涉及一种用于涂覆材料表面的方法，包括以下步骤：（a）将包含烯键式不饱和双键的化合物共价结合到所述材料表面;（b）在表面上聚合包含反应性或可交联基团的单体 从而提供包含反应性或可交联基团的初级聚合物涂层，（c）在步骤（b）中包含反应性基团的单体的情况下，使初级涂层的反应性基团与包含烯属不饱和双键的另外的化合物和接枝 在步骤（b）或（c）中存在可交联基团的情况下，将亲水性单体和任选的具有可交联基团的共聚单体聚合到根据步骤（b）和（d）获得的初级涂层上，引发所述 团体 通过本发明的方法可获得的涂覆制品具有关于对基材的粘附性，耐久性，亲水性，润湿性，生物相容性和渗透性的所需特性，因此可用于制造生物医学制品如眼科装置。
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公开(公告)号：US08795782B2
公开(公告)日：2014-08-05
申请号：US13355072
申请日：2012-01-20
IPC分类号： C09D201/02 , C08L101/02
CPC分类号： C08J7/16 , C08F2438/03
摘要： The present invention relates to a controllable polymeric surface coating including a macromolecule, which is covalently bound to the surface of a substrate, the macromolecule including a plurality of polymerization initiators and a plurality of surface binding groups. Pendant polymers may be grafted from at least some of the polymerization initiators.
摘要翻译： 本发明涉及一种可控制的聚合物表面涂层，其包括共价结合到基底表面的大分子，该大分子包括多个聚合引发剂和多个表面结合基团。 侧链聚合物可以从至少一些聚合引发剂接枝。
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公开(公告)号：US08124188B2
公开(公告)日：2012-02-28
申请号：US11840523
申请日：2007-08-17
IPC分类号： C09D201/02 , C08L101/02
CPC分类号： C08J7/123
摘要： The present invention relates to a controllable polymeric surface coating including a macromolecule, which is covalently bound to the surface of a substrate, the macromolecule including a plurality of polymerization initiators and a plurality of surface binding groups; and pendant polymers grafted from at least some of the polymerization initiators.
摘要翻译： 本发明涉及可控制的聚合物表面涂层，其包括共价结合到基底表面的大分子，该大分子包括多个聚合引发剂和多个表面结合基团; 和从至少一些聚合引发剂接枝的侧链聚合物。
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公开(公告)号：US20120178165A1
公开(公告)日：2012-07-12
申请号：US13355072
申请日：2012-01-20
CPC分类号： C08J7/16 , C08F2438/03
摘要： The present invention relates to a controllable polymeric surface coating including a macromolecule, which is covalently bound to the surface of a substrate, the macromolecule including a plurality of polymerisation initiators and a plurality of surface binding groups. Pendant polymers may be grafted from at least some of the polymerisation initiators.
摘要翻译： 本发明涉及可控制的聚合物表面涂层，其包括共价结合到基底表面的大分子，该大分子包括多个聚合引发剂和多个表面结合基团。 侧链聚合物可以从至少一些聚合引发剂接枝。
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公开(公告)号：US20080045686A1
公开(公告)日：2008-02-21
申请号：US11840523
申请日：2007-08-17
申请人： Laurence Meagher , Helmut Thissen , Paul Pasic , Richard Evans , Graham Johnson
发明人： Laurence Meagher , Helmut Thissen , Paul Pasic , Richard Evans , Graham Johnson
IPC分类号： C08F120/18
CPC分类号： C08J7/123
摘要： The present invention relates to a controllable polymeric surface coating including a macromolecule, which is covalently bound to the surface of a substrate, the macromolecule including a plurality of polymerisation initiators and a plurality of surface binding groups; and pendant polymers grafted from at least some of the polymerisation initiators.
摘要翻译： 本发明涉及可控制的聚合物表面涂层，其包括共价结合到基底表面的大分子，该大分子包括多个聚合引发剂和多个表面结合基团; 和从至少一些聚合引发剂接枝的侧链聚合物。
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