摘要:
A method of assaying a physiologically active substance, which comprises activating blood coagulation factor XII in plasma in the presence of said physiologically active substance being tested to convert prekallikrein in the plasma into kallikrein, and measuring the activity of kallikrein thus formed.
摘要:
Parabanic acid compound of the formula (I): ##STR1## wherein R is hydrogen or a lower alkyl group, X is hydrogen, an alkyl group, a cycloalkyl group, a lower alkylcycloalkyl group, a phenyl group or a phenalkyl group, and n represents an integer of 1 to 4, exhibit excellent aldose reductase inhibitory activity and are useful as drugs for treating or prevention of complications of diabetes.
摘要:
This invention relates to novel vincamine derivatives useful as cerebral metabolic and circulatory regulators. The compounds have the following structural formula: ##STR1## wherein R.sub.1 is hydrogen or a hydroxyl group and R.sub.2 is an alkyl group.
摘要:
A physiologically active substance is extracted from infected tissues inoculated with a poxvirus. The novel substance of the present invention has inhibitory action against the formation of kallikrein, thus is useful as drugs such as antiinflammatory, analgesic and antiallergic agents.