公开(公告)号：US08317826B2

公开(公告)日：2012-11-27

申请号：US12587461

申请日：2009-10-07

申请人： Young Hwan Park ,  Jung Nam Im ,  Jae Hoon Ko ,  Kyoung Woo Lee ,  Yong Woo Cho

发明人： Young Hwan Park ,  Jung Nam Im ,  Jae Hoon Ko ,  Kyoung Woo Lee ,  Yong Woo Cho

IPC分类号： A61B17/04 ,  A61F13/00

CPC分类号： A61B17/06166 ,  A61B2017/00526 ,  A61B2017/00893 ,  A61L17/10 ,  A61L27/58 ,  D02G1/0286 ,  D02G1/20 ,  D02G3/448

摘要： An absorbable multifilament draw-textured yarn having a bulky structure, and a manufacturing method and medical use thereof The absorbable multifilament draw-textured yarn is obtained by draw-texturing a multifilament made of an absorbable polymer and has bulkiness and a superior soft touch, which are the characteristics of draw-textured yarns. As a result of partially imparting a bulkiness of 150-1000% to the multifilament draw-textured yarn, it is possible to culture cells in the bulky structure, and the multifilament draw-textured yarn is suitable for cell delivery or drug delivery.

摘要翻译： 一种具有体积庞大结构的可吸收复丝拉伸加工纱线及其制造方法和医疗用途可吸收复丝拉伸加工纱线通过拉伸变形由可吸收聚合物制成的复丝而获得，并且具有蓬松性和优异的柔软触感， 是拉伸变形纱线的特征。 由于部分地赋予复丝拉伸变形纱线的150-1000％的膨松度，所以可以将细胞培养成体积大的结构，并且复丝拉伸加工纱线适合于细胞递送或药物递送。

公开(公告)号：US20100087856A1

公开(公告)日：2010-04-08

申请号：US12587461

申请日：2009-10-07

申请人： Young Hwan Park ,  Jung Nam Im ,  Jae Hoon Ko ,  Kyoung Woo Lee ,  Yong Woo Cho

发明人： Young Hwan Park ,  Jung Nam Im ,  Jae Hoon Ko ,  Kyoung Woo Lee ,  Yong Woo Cho

IPC分类号： A61L17/06 ,  D02G1/20 ,  D02G3/02 ,  D02G3/24 ,  A61B17/04

CPC分类号： A61B17/06166 ,  A61B2017/00526 ,  A61B2017/00893 ,  A61L17/10 ,  A61L27/58 ,  D02G1/0286 ,  D02G1/20 ,  D02G3/448

摘要： An absorbable multifilament draw-textured yarn having a bulky structure, and a manufacturing method and medical use thereof The absorbable multifilament draw-textured yarn is obtained by draw-texturing a multifilament made of an absorbable polymer and has bulkiness and a superior soft touch, which are the characteristics of draw-textured yarns. As a result of partially imparting a bulkiness of 150-1000% to the multifilament draw-textured yarn, it is possible to culture cells in the bulky structure, and the multifilament draw-textured yarn is suitable for cell delivery or drug delivery.

摘要翻译： 一种具有体积庞大结构的可吸收复丝拉伸加工纱线及其制造方法和医疗用途可吸收复丝拉伸加工纱线通过拉伸变形由可吸收聚合物制成的复丝而获得，并且具有蓬松性和优异的柔软触感， 是拉伸变形纱线的特征。 由于部分地赋予复丝拉伸变形纱线的150-1000％的膨松度，所以可以将细胞培养成体积大的结构，并且复丝拉伸加工纱线适合于细胞递送或药物递送。

公开(公告)号：US07511023B2

公开(公告)日：2009-03-31

申请号：US10473629

申请日：2002-08-14

申请人： Ick Chan Kwon ,  In-San Kim ,  Seo Young Jeong ,  Hesson Chung ,  Yong Woo Cho ,  Yoen Ju Son ,  Chong Rae Park ,  Sang Bong Seo

发明人： Ick Chan Kwon ,  In-San Kim ,  Seo Young Jeong ,  Hesson Chung ,  Yong Woo Cho ,  Yoen Ju Son ,  Chong Rae Park ,  Sang Bong Seo

IPC分类号： A01N43/04 ,  A61K31/70

CPC分类号： A61K31/704 ,  A61K47/61 ,  A61K47/6907

摘要： The present invention relates to an anticancer drug-chitosan complex forming self-aggregates and the preparation method thereof. More precisely, the present invention relates to the anticancer drug-chitosan complex forming self-aggregates in aqueous media composed of a hydrophobic anticancer agent and a hydrophilic chitosan, and the preparation method thereof. The anticancer drug-chitosan complex of the present invention not only works selectively against target tumor tissue but also continues to release the medicine over a long period of time. Besides, the anticancer drug-chitosan complex could have greater amount of drug by adding the anticancer drug into self-aggregates, which is generally limited by chemical bond. Therefore, the anticancer drug-chitosan complex of the present invention can be effectively used for the cancer chemotherapy.

摘要翻译： 本发明涉及形成自聚集体的抗癌药物 - 壳聚糖复合物及其制备方法。 更准确地说，本发明涉及在由疏水性抗癌剂和亲水性壳聚糖组成的水性介质中形成自聚集体的抗癌药物 - 壳聚糖复合物及其制备方法。 本发明的抗癌药物 - 壳聚糖复合物不仅对目标肿瘤组织有选择性的作用，而且还能够长时间地释放药物。 此外，抗癌药物 - 壳聚糖复合物可以通过将抗癌药物加入自聚集体中而具有更大量的药物，其通常受化学键的限制。 因此，本发明的抗癌药物 - 壳聚糖复合物可以有效地用于癌症化疗。