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公开(公告)号:US20120136025A1
公开(公告)日:2012-05-31
申请号:US13364815
申请日:2012-02-02
申请人: Yuji KOGA , Takao OKUDA , Susumu WATANUKI , Takashi KAMIKUBO , Fukushi HIRAYAMA , Hiroyuki MORITOMO , Jiro FUJIYASU , Michihito KAGEYAMA , Toshio UEMURA , Jun TAKASAKI
发明人: Yuji KOGA , Takao OKUDA , Susumu WATANUKI , Takashi KAMIKUBO , Fukushi HIRAYAMA , Hiroyuki MORITOMO , Jiro FUJIYASU , Michihito KAGEYAMA , Toshio UEMURA , Jun TAKASAKI
IPC分类号: A61K31/47 , A61P9/00 , A61P7/02 , C07D215/22
CPC分类号: C07D513/04 , C07D215/22 , C07D215/56 , C07D401/04 , C07D401/12 , C07D401/14 , C07D405/04 , C07D405/12 , C07D409/14 , C07D413/12 , C07D417/12 , C07D417/14 , C07D471/14 , C07D487/04 , C07F7/1804 , C07F9/60
摘要: Disclosed are quinolone derivatives characterized in that these have lower alkyl, cycloalkyl or the like at the 1-position; —N(R0)C(O)-lower alkylene-CO2R0, lower alkylene-CO2R0, lower alkenylene-CO2R0, —O-lower alkylene-CO2R0, —O-(lower alkylene which may be substituted with —CO2R0)-aryl or —O-lower alkenylene-CO2R0 (wherein R0 is H or lower alkyl) at the 3-position; halogen at the 6-position; and amino group substituted with a substituent group having a ring structure at the 7-position, respectively, or pharmaceutically acceptable salts thereof, has excellent P2Y12 inhibitory activity. The quinolone derivatives have excellent platelet aggregation inhibitory activity. A method of using the compounds is also disclosed.
摘要翻译: 公开了喹诺酮衍生物,其特征在于它们在1-位具有低级烷基,环烷基等; -N(R 0)C(O) - 低级亚烷基-CO 2 R 0,低级亚烷基-CO 2 R 0,低级亚烯基-CO 2 R O,-O-低级亚烷基-CO 2 R O,-O-(可被-CO 2 R 0取代的低级亚烷基) - 芳基或 O-低级亚烯基-CO 2 R 0(其中R 0是H或低级烷基)在3-位; 6位卤素; 分别被具有7位具有环结构的取代基取代的氨基或其药学上可接受的盐具有优异的P2Y12抑制活性。 喹诺酮衍生物具有优异的血小板聚集抑制活性。 还公开了使用该化合物的方法。
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公开(公告)号:US20090124617A1
公开(公告)日:2009-05-14
申请号:US12347428
申请日:2008-12-31
申请人: Susumu WATANUKI , Yuji KOGA , Hiroyuki MORITOMO , Issei TSUKAMOTO , Daisuke KAGA , Takao OKUDA , Fukushi HIRAYAMA , Yumiko MORITANI , Jun TAKASAKI
发明人: Susumu WATANUKI , Yuji KOGA , Hiroyuki MORITOMO , Issei TSUKAMOTO , Daisuke KAGA , Takao OKUDA , Fukushi HIRAYAMA , Yumiko MORITANI , Jun TAKASAKI
IPC分类号: A61K31/5377 , C07D215/233 , A61K31/47 , C07D401/12 , C07D471/04 , C07D237/26 , A61K31/4725 , A61P7/00 , A61K31/536 , A61K31/4375 , A61K31/496 , C07D405/12 , C07D413/12
CPC分类号: C07D237/28 , A61K31/4709 , A61K31/4725 , C07D215/56 , C07D405/04 , C07F9/5765 , C07F9/60 , C07F9/650947
摘要: A platelet aggregation inhibitor comprising a quinolone derivative or a pharmaceutically acceptable salt thereof as an active ingredient, and a novel quinolone derivative or a pharmaceutically acceptable salt thereof useful as a platelet aggregation inhibitor.
摘要翻译: 包含喹诺酮衍生物或其药学上可接受的盐作为活性成分的血小板聚集抑制剂和用作血小板聚集抑制剂的新型喹诺酮衍生物或其药学上可接受的盐。
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公开(公告)号:US20100222361A1
公开(公告)日:2010-09-02
申请号:US12615968
申请日:2009-11-10
申请人: Keizo SUGASAWA , Susumu WATANUKI , Yuji KOGA , Hiroshi NAGATA , Ryutaro WAKAYAMA , Fukushi HIRAYAMA , Ken-ichi SUZUKI
发明人: Keizo SUGASAWA , Susumu WATANUKI , Yuji KOGA , Hiroshi NAGATA , Ryutaro WAKAYAMA , Fukushi HIRAYAMA , Ken-ichi SUZUKI
IPC分类号: A61K31/497 , A61P7/00
CPC分类号: C07D417/14 , A61K31/426 , A61K31/427 , A61K31/439 , A61K31/4545 , A61K31/4709 , A61K31/496 , A61K31/497 , A61K31/498 , A61K31/506 , A61K31/5377 , A61K31/538 , A61K31/695 , C07D277/46 , C07D417/04 , C07D417/12 , C07D453/02
摘要: A 2-acylaminothiazole derivative or a pharmaceutically acceptable salt thereof having an excellent effect of proliferating human c-mpl-Ba/F3 cells and an activity of increasing platelets based on the effect of promoting the formation of megakaryocytic colonies. A compound or a pharmaceutically acceptable salt thereof useful in treating thrombocytopenia.
摘要翻译: 基于促进巨核细胞集落形成的效果,具有对人c-mpl-Ba / F3细胞增殖的优异效果的2-酰基氨基噻唑衍生物或其药学上可接受的盐和增加血小板的活性。 用于治疗血小板减少症的化合物或其药学上可接受的盐。
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公开(公告)号:US20150336409A1
公开(公告)日:2015-11-26
申请号:US14816592
申请日:2015-08-03
申请人: Yuji KOGA , Masatoshi IZUCHI
发明人: Yuji KOGA , Masatoshi IZUCHI
CPC分类号: B41J25/006 , B41J2/01 , B41J11/485 , B41J13/0018 , B41J13/009 , B41J19/202 , B41J23/02 , B41J23/14 , B41J25/001 , B41J25/34
摘要: A printer has a carriage being movable between a first end and a second end of a reciprocating path; and a driving force transmitting path selecting mechanism provided at the second end of the reciprocating path. The selecting mechanism has: a common driving force outputting member; a plurality of force receiving members; a selecting member; and a position retainer for keeping the position of the selecting member. The selecting member connects the force outputting member to one of the plurality of force receiving members, and moves in association with the carriage when the carriage moves in a vicinity of the second end in a first direction extending from the first end to the second end. The position retainer keeps the position of the selecting member when the carriage moves in a second direction extending from the second end to the first end. The force receiving member connected to the force outputting member via the selecting member is selected in accordance with a movement of the carriage along the reciprocating path.
摘要翻译: 打印机具有可在往复路径的第一端和第二端之间移动的托架; 以及设置在往复路径的第二端的驱动力传递路径选择机构。 所述选择机构具有:共同的驱动力输出部件; 多个受力构件; 选择成员; 以及用于保持选择构件的位置的位置保持器。 所述选择构件将所述力输出构件连接到所述多个力接收构件中的一个,并且当所述滑架在所述第二端附近沿着从所述第一端延伸到所述第二端的第一方向移动时与所述滑架相关联地移动。 当滑架沿着从第二端延伸到第一端的第二方向移动时,位置保持器保持选择构件的位置。 根据滑架沿往复路径的移动来选择经由选择构件连接到力输出构件的受力构件。
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公开(公告)号:US20140043420A1
公开(公告)日:2014-02-13
申请号:US14060428
申请日:2013-10-22
申请人: Noriyuki KAWAMATA , Yuji KOGA , Wataru SUGIYAMA , Kenji SAMOTO
发明人: Noriyuki KAWAMATA , Yuji KOGA , Wataru SUGIYAMA , Kenji SAMOTO
IPC分类号: B41J13/03
CPC分类号: B41J11/04 , B41J2/01 , B41J13/025 , B41J13/03 , B65H5/062 , B65H2402/31 , B65H2402/5152 , B65H2404/1521 , B65H2404/174
摘要: There is provided an image recording apparatus including a transporting path, a recording section, a first and second rollers pinching the recording medium therebetween, a supporting member which rotatably supports the second roller, a holding member which is movable along a transporting direction of the recording medium, a bias applying member which applies a bias on the holding member, in an opposite direction opposite to the transporting direction and a load member which generates a load in the opposite direction, with respect to the recording medium.
摘要翻译: 提供了一种图像记录装置,包括传送路径,记录部分,夹在其间的记录介质的第一和第二辊;支撑部件,其可旋转地支撑第二辊;保持部件,其可沿着记录的传送方向移动 介质,相对于记录介质,在与传送方向相反的方向上相对于保持构件施加偏压的偏置施加构件和产生相反方向的负载的负载构件。
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公开(公告)号:US20130140764A1
公开(公告)日:2013-06-06
申请号:US13691237
申请日:2012-11-30
申请人: Kenji SAMOTO , Yuji KOGA , Takashi OMURA
发明人: Kenji SAMOTO , Yuji KOGA , Takashi OMURA
IPC分类号: B65H85/00
CPC分类号: B65H85/00 , B65H3/0684 , B65H5/38 , B65H7/02 , B65H2301/33312 , B65H2404/6111 , B65H2405/3322 , B65H2511/212 , B65H2511/417 , B65H2601/523 , B65H2801/12 , B65H2220/01 , B65H2220/11 , B65H2220/03
摘要: An image forming apparatus has a rockable member which is configured to rotate about an axis defined at a first end portion among: a first position at which a second end portion at a downstream side in the forward feed direction with respect to the first end portion is supported by the guide member having the first orientation; a second position at which the second end portion is located at a higher position that the second end portion when located at the first position; and a third position at which the second end portion is located at a lower position that the second end portion when located at the first position; and a signal generating unit configured to output a signal corresponding to the position of the rockable member. A photo sensor is provided to generate a signal in accordance with an orientation of the rockable member.
摘要翻译: 图像形成装置具有可摆动构件,该摆动构件被构造成围绕限定在第一端部处的轴线旋转:第一位置,在第一位置处,相对于第一端部在前进方向的下游侧的第二端部为 由具有第一取向的引导构件支撑; 第二位置,其中第二端部位于第二端部处于第一位置的较高位置处; 以及第三位置,在所述第三位置,所述第二端部位于所述第二端部处于所述第一位置的下位置处; 以及信号生成单元,被配置为输出与所述可摆动构件的位置相对应的信号。 提供光传感器以根据可摆动构件的取向产生信号。
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公开(公告)号:US20120080834A1
公开(公告)日:2012-04-05
申请号:US13315227
申请日:2011-12-08
申请人: Yukio SHIOHARA , Tetsuo ASADA , Yuji KOGA
发明人: Yukio SHIOHARA , Tetsuo ASADA , Yuji KOGA
CPC分类号: B65H3/44 , B41J11/485 , B41J13/103 , B65H1/04 , B65H1/22 , B65H1/266 , B65H1/28 , B65H3/0669 , B65H3/66 , B65H2301/422548 , B65H2405/32 , B65H2405/332 , B65H2601/322 , B65H2701/1131 , G06K15/102 , H04N1/0057 , H04N1/00602 , H04N1/00604 , H04N1/00623 , H04N2201/0094
摘要: An image recording apparatus including a first tray having a first holding portion for holding sheets, a second tray disposed above the first tray and including a second holding portion for holding sheets, a sheet feeder that selectively feeds a sheet from one of the first tray and the second tray in a sheet feed direction, a recording unit that records an image on the sheet fed by the sheet feeder, and a discharge roller that discharges the sheet on which the image is recorded by the recording unit. The second holding portion of the second tray moves above the first holding portion of the first tray. The second tray further includes a discharged sheet receiving portion for receiving the sheet discharged by the discharge roller. The second tray including the discharged sheet receiving portion pivots relative to the first tray.
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公开(公告)号:US20110310207A1
公开(公告)日:2011-12-22
申请号:US13072742
申请日:2011-03-27
申请人: Tsuyoshi ITO , Kensuke HIRATE , Yuji KOGA
发明人: Tsuyoshi ITO , Kensuke HIRATE , Yuji KOGA
IPC分类号: B41J2/01
CPC分类号: B65H31/22 , B65H5/38 , B65H29/52 , B65H85/00 , B65H2301/33312 , B65H2402/46 , B65H2404/693 , B65H2405/3322 , B65H2601/11 , B65H2801/06
摘要: An image recording device comprises a housing, a sheet cassette, a recording unit, and a convey path defining member. The housing has an opening. The sheet cassette is configured to hold therein sheets and configured to be inserted into and removed from the housing through the opening. The recording unit is configured to record an image on a sheet conveyed from the sheet cassette along a convey path. The convey path defining member is configured to pivot, about a pivot shaft supported by the housing, between a guiding position for forming a guide surface that defines a part of the convey path, and an exposing position for exposing the part of the convey path to the opening. The convey path defining member is configured to pivot in response to insertion and removal of the sheet cassette.
摘要翻译: 图像记录装置包括壳体,薄片盒,记录单元和传送路径限定部件。 房屋有一个开口。 片材盒被配置为保持其中的片材并且构造成通过开口插入到壳体中并从壳体移除。 记录单元被配置为沿着传送路径将图像记录在从片材盒传送的片材上。 输送路径限定构件被构造成围绕由壳体支撑的枢转轴枢转在用于形成限定输送路径的一部分的引导表面的引导位置和用于将输送路径的部分暴露于 开幕。 输送路径限定构件被配置为响应于片材盒的插入和移除而枢转。
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公开(公告)号:US20110310145A1
公开(公告)日:2011-12-22
申请号:US13072753
申请日:2011-03-27
申请人: Kenji SAMOTO , Yuji KOGA , Keisuke WAKAKUSA
发明人: Kenji SAMOTO , Yuji KOGA , Keisuke WAKAKUSA
IPC分类号: B41J29/38
CPC分类号: B41J11/42 , B41J11/0095
摘要: A multifunction machine includes: a first feeding roller and a second feeding roller; an intermediate roller pair provided to a curved portion of a transport route; a main transporting roller pair; a recording head; a first drive motor and a second drive motor; and a control section. The control section intermittently drives the main transporting roller pair and makes the recording head jet ink during a period of time in which the main transporting roller pair is stopped, and performs pre-paper feeding processing for rotating the first feeding roller a predetermined amount in a paper feeding direction when a rear end of a paper is positioned between a first sensor and the first feeding roller.
摘要翻译: 多功能机包括:第一进给辊和第二进给辊; 设置在运输路线的弯曲部分的中间辊对; 主输送辊对; 录音头 第一驱动马达和第二驱动马达; 和控制部分。 控制部分间歇地驱动主传送辊对,并使记录头在主传送辊对停止的时间段内喷射墨水,并且执行用于将第一进给辊旋转预定量的预纸进给处理 当纸的后端位于第一传感器和第一进给辊之间时,送纸方向。
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公开(公告)号:US20160129711A1
公开(公告)日:2016-05-12
申请号:US14997224
申请日:2016-01-15
申请人: Yuji KOGA , Masatoshi IZUCHI
发明人: Yuji KOGA , Masatoshi IZUCHI
CPC分类号: B41J25/006 , B41J2/01 , B41J11/485 , B41J13/0018 , B41J13/009 , B41J19/202 , B41J23/02 , B41J23/14 , B41J25/001 , B41J25/34
摘要: A printer has a carriage being movable between a first end and a second end of a reciprocating path; and a driving force transmitting path selecting mechanism provided at the second end of the reciprocating path. The selecting mechanism has: a common driving force outputting member; a plurality of force receiving members; a selecting member; and a position retainer for keeping the position of the selecting member. The selecting member connects the force outputting member to one of the plurality of force receiving members, and moves in association with the carriage when the carriage moves in a vicinity of the second end in a first direction extending from the first end to the second end. The position retainer keeps the position of the selecting member when the carriage moves in a second direction extending from the second end to the first end. The force receiving member connected to the force outputting member via the selecting member is selected in accordance with a movement of the carriage along the reciprocating path.
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