摘要:
The invention provides peptides that are chemically modified by covalent attachment of a water-soluble oligomer. A conjugate of the invention, when administered by any of a number of administration routes, exhibits characteristics that are different from the characteristics of the peptide not attached to the water-soluble oligomer.
摘要:
The invention provides peptides that are chemically modified by covalent attachment of a water soluble oligomer. A conjugate of the invention, when administered by any of a number of administration routes, exhibits characteristics that are different from the characteristics of the peptide not attached to the water soluble oligomer.
摘要:
The invention provides protegrin that are chemically modified by covalent attachment of a water soluble oligomer. A conjugate of the invention has enhanced half-life and/or reduced clearance.
摘要:
Conjugates of an interleukin-2 (“IL-2”) moiety and one or more nonpeptidic, water-soluble polymers are provided. Typically, the nonpeptidic, water-soluble polymer is poly(ethylene glycol) or a derivative thereof. Also provided, among other things, are compositions comprising conjugates, methods of making conjugates, methods of administering compositions to an individual, nucleic acid sequences, expression systems, host cells, and methods for preparing IL-moieties.
摘要:
A method and apparatus for capturing database system workload and replaying that workload in a database system is provided. According to one aspect, in order to subject a test database system to the same workload to which the production database system actually would be subjected, a database server in the production system captures and records workload that the database server receives from external entities. This captured workload is processed. Processes external to a database server in the test database system send the processed workload to that database server. As a result, the test database system is subjected to the same workload to which the production database system originally was subjected. The foregoing technique permits a database administrator to determine how the production database system will fare if the difference that is present in the test database system is introduced into the production database system.
摘要:
A method for replaying a simulation workload is provided. The simulation workload identifies a plurality of workload parts. Each workload part is at least a portion of a respective captured workload. In an embodiment, a first workload part is a portion of a first workload executed relative to a first capture database server and a second workload part is a portion of a second workload executed relative to a second capture database server. A portion of the first workload part and a portion of the second workload part may be replayed concurrently.
摘要:
A method and apparatus for capturing database system workload and replaying that workload in a database system is provided. According to one aspect, in order to subject a test database system to the same workload to which the production database system actually would be subjected, a database server in the production system captures and records workload that the database server receives from external entities. This captured workload is processed. Processes external to a database server in the test database system send the processed workload to that database server. As a result, the test database system is subjected to the same workload to which the production database system originally was subjected. The foregoing technique permits a database administrator to determine how the production database system will fare if the difference that is present in the test database system is introduced into the production database system.
摘要:
A method for replaying a simulation workload is provided. The simulation workload identifies a plurality of workload parts. Each workload part is at least a portion of a respective captured workload. In an embodiment, a first workload part is a portion of a first workload executed relative to a first capture database server and a second workload part is a portion of a second workload executed relative to a second capture database server. A portion of the first workload part and a portion of the second workload part may be replayed concurrently.
摘要:
To provide a new natural fiber material with excellent physical properties. Any one of the following nucleic acids (a) to (d): (a) a nucleic acid having a base sequence of SEQ ID NO: 1 or 19; (b) a nucleic acid encoding a protein having an amino acid sequence of SEQ ID NO: 2 or 20; (c) a nucleic acid encoding a dragline protein and having a sequence identity of 90% or more with the nucleic acid (a); (d) a nucleic acid which encodes a dragline protein and hybridizes with a complementary chain of the nucleic acid (a) under stringent conditions.
摘要翻译:提供具有优异物理性能的新型天然纤维材料。 以下核酸(a)至(d)中的任一种:(a)具有SEQ ID NO:1或19的碱基序列的核酸; (b)编码具有SEQ ID NO:2或20的氨基酸序列的蛋白质的核酸; (c)与核酸(a)具有90%或更高的序列同一性的编码牵引蛋白的核酸; (d)编码牵引蛋白并在严格条件下与核酸(a)的互补链杂交的核酸。
摘要:
A method, apparatus, and computer-readable medium is provided for replaying captured workload data in a database environment with connection pools. A replay system includes a dispatcher that manages a connection pool. In one aspect, the dispatcher selects available connections for sending database commands that are ready to be executed against a database, but prevents from being sent, or holds, commands that are not ready to be executed against the database. Commands may be stored at the dispatcher until the database advances to a state that allows the commands to be executed. In another aspect, the dispatcher may use an available connection to send a command to a database instance even though the command is not ready to be executed, as long as at least a threshold number or percentage of connections remains available.