公开(公告)号：US5239171A

公开(公告)日：1993-08-24

申请号：US842256

申请日：1992-02-27

申请人： Yutaka Takabayashi ,  Hiromi Utsunomiya ,  Takashi Nagano ,  Jitsunari Kojima

发明人： Yutaka Takabayashi ,  Hiromi Utsunomiya ,  Takashi Nagano ,  Jitsunari Kojima

IPC分类号： G02B21/36

CPC分类号： G02B21/365

摘要： A photographing apparatus for microscopes is constructed so that a simultaneous observation is made by overlapping an image of a sample formed by transmitted illumination with that formed by reflected fluorescence, in which signals for designating the simultaneous observation at once cause a second shutter for the transmitted illumination to be closed and a first shutter for the reflected fluorescence to be opened, the brightness of the sample image formed by the reflected fluorescence is measured by a light-detecting element disposed in an optical path for observation, and after a light-adjusting member for the transmitted illumination is controlled so that, based on data outputted from a memory device corresponding to a measured value, the brightness of the sample image by the transmitted illumination in the simultaneous observation is balanced with that of the sample image by the reflected fluorescence, the second shutter is opened. Thus, this photographing apparatus has advantages that whenever the microscopy is switched, an operator can dispense with the need for a fine adjustment of the amount of transmitted illumination light, with the resultant ease of operation, the balance adjustment of brightness in switching is made in a short time, and the bleaching of fluorescence of the sample can be suppressed.

公开(公告)号：US5260825A

公开(公告)日：1993-11-09

申请号：US742517

申请日：1991-08-06

申请人： Takashi Nagano ,  Jitsunari Kojima

发明人： Takashi Nagano ,  Jitsunari Kojima

IPC分类号： G02B7/16 ,  G02B21/24 ,  G02B21/00 ,  G01J1/20

CPC分类号： G02B21/241 ,  G02B7/16

摘要： A microscope has a plural number of objective lenses switchable from one to another, a memory circuit for storing parfocality data for the individual objective lenses, and a correcting device for correcting imaging conditions on the basis of the parfocality data for an objective lens currently used and another objective lens to be selected for microscopy. The microscope is capable of always providing favorably focused condition even when the objective lenses are switched from one to another for changing observation magnification levels.

摘要翻译： 显微镜具有可从一个切换到另一个的多个物镜，用于存储用于各个物镜的parfocality数据的存储电路，以及用于基于当前使用的物镜的parfocality数据校正成像条件的校正装置，以及 用于显微镜的另一个物镜。 即使当物镜从一个切换到另一个以改变观察放大水平时，显微镜也能始终提供有利的聚焦状态。

公开(公告)号：US6043475A

公开(公告)日：2000-03-28

申请号：US839658

申请日：1997-04-15

申请人： Masakazu Shimada ,  Takashi Nagano ,  Takashi Yoneyama ,  Nobuyuki Nagasawa ,  Hideaki Endo ,  Jitsunari Kojima ,  Atsuhiro Tsuchiya ,  Yukiko Saeki

发明人： Masakazu Shimada ,  Takashi Nagano ,  Takashi Yoneyama ,  Nobuyuki Nagasawa ,  Hideaki Endo ,  Jitsunari Kojima ,  Atsuhiro Tsuchiya ,  Yukiko Saeki

IPC分类号： G02B21/24 ,  G02B7/04

CPC分类号： G02B21/241

摘要： A focal point adjustment apparatus applied to an optical apparatus with a projection optical system, comprises, an object lens, a stage on which a plate member on which a subject is put for measurement is placed, provision unit for providing the thickness of the plate member for measurement, determining unit for determining data on the distance between the object lens and the stage on the basis of the thickness of the plate member for measurement provided by the provision unit, and focusing unit for adjusting the distance between the object lens and the stage on the basis of the data on the distance between the object lens and the stage determined by the determining unit.

摘要翻译： 一种应用于具有投影光学系统的光学装置的焦点调节装置，包括：物镜，放置有被测体放置用于测量的板构件的台，提供单元，用于提供板构件的厚度 用于测量的确定单元，用于基于由提供单元提供的用于测量的板构件的厚度来确定物镜与台架之间的距离的数据;以及聚焦单元，用于调整物镜与舞台之间的距离 基于由所述确定单元确定的所述物镜与所述台阶之间的距离的数据。

公开(公告)号：US06917377B2

公开(公告)日：2005-07-12

申请号：US09775005

申请日：2001-02-01

申请人： Shinichiro Aizaki ,  Mitsuhiko Saito ,  Jitsunari Kojima ,  Hitoshi Ueda ,  Hideyuki Masuyama

发明人： Shinichiro Aizaki ,  Mitsuhiko Saito ,  Jitsunari Kojima ,  Hitoshi Ueda ,  Hideyuki Masuyama

IPC分类号： G02B21/36 ,  H04N5/235 ,  H04N7/18

CPC分类号： H04N5/2352 ,  G02B21/365

摘要： A microscope system provided by the present invention in which an electronic camera is used to pick up an observation image by a microscope, comprising a controlling section for setting an image pickup operation of an image pickup element in the electronic camera to an optimum state in accordance with a state of at least one of an optical system combination for a projection magnification of at least an objective lens and a photo eyepiece on a microscope side, an observation method, and lighting conditions.

摘要翻译： 由本发明提供的显微镜系统，其中电子照相机用于通过显微镜拾取观察图像，包括控制部分，用于将电子照相机中的图像拾取元件的图像拾取操作设置为最佳状态 具有用于显微镜侧的至少物镜和照片目镜的投影放大率的光学系统组合，观察方法和照明条件中的至少一个的状态。

公开(公告)号：US5703714A

公开(公告)日：1997-12-30

申请号：US592448

申请日：1996-01-26

申请人： Jitsunari Kojima

发明人： Jitsunari Kojima

IPC分类号： G02B21/00 ,  G02B21/06 ,  G02B21/36

CPC分类号： G02B21/06

摘要： A microscope apparatus includes a light source for generating illumination light, an illumination optical system for illuminating an object to be observed with the illumination light, and an observation optical system for conducting an observation image of the illuminated object to an observation site. An objective change unit is arranged in the observation optical system for holding a plurality of objectives and for selectively inserting one of the objectives onto an optical path of the observation optical system. An optical system controller, which independently controls an optical element arranged in the illumination optical system and independently controls an optical element arranged in the observation optical system, includes a frame controller for controlling the objective change unit to insert one of the plurality of objectives selected onto the optical path of the observation optical system. A recognition unit recognizes one of a plurality of predetermined observation methods designated by the observer. A memory has a table for registering setting conditions of the optical elements which correspond to the respective observation methods, and fit/unfit information indicating whether or not each of the plurality of objectives is fit for the respective observation methods. A fit determination module operates in accordance with the fit/unfit information registered in the table of the memory for: (i) when the observer designates the observation method, determining whether or not the designated observation method is fit for the selected objective, and (ii) when the observer selects the objective, determining whether or not the selected objective is fit for the designated observation method.

摘要翻译： 显微镜装置包括用于产生照明光的光源，用照明光照射被观察物体的照明光学系统和用于将被照明物体的观察图像导向观察部位的观察光学系统。 在观察光学系统中设置物镜改变单元，用于保持多个物镜并且将目标中的一个选择性地插入到观察光学系统的光路上。 独立地控制布置在照明光学系统中的光学元件并独立地控制布置在观察光学系统中的光学元件的光学系统控制器包括：帧控制器，用于控制物镜改变单元将所选择的多个目标中的一个物体插入到 观察光学系统的光路。 识别单元识别由观察者指定的多个预定观察方法中的一个。 存储器具有用于登记与各观察方法对应的光学元件的设定条件的表，以及指示多个目标中的每一个是否适合于各个观察方法的拟合/不适合信息。 拟合确定模块根据登记在存储器表中的拟合/不合格信息进行操作，用于：（i）当观察者指定观察方法时，确定指定的观察方法是否适合所选择的目标，以及（ ii）当观察者选择目标时，确定所选择的目标是否适合指定的观察方法。

公开(公告)号：US20090185034A1

公开(公告)日：2009-07-23

申请号：US12354032

申请日：2009-01-15

申请人： Hironori KISHIDA ,  Jitsunari Kojima

发明人： Hironori KISHIDA ,  Jitsunari Kojima

IPC分类号： H04N7/18

CPC分类号： G02B21/365 ,  H04N5/23296 ,  H04N5/235

摘要： An image pickup unit obtains a specimen image by picking up the observation image of a specimen produced by a microscope. An installation state information obtainment unit obtains installation state information indicating the installation state of an optical member inserted into the observation light path of the microscope. An exposure condition setup unit sets an exposure condition to be used when the image pickup unit picks up the observation image to obtain a specimen image in a second magnification ratio, on the basis of installation state information used when the image pickup unit obtained a specimen image in a first magnification ratio by picking up the observation image, and on the basis of installation state information to be used when the image pickup unit obtains a specimen image in the second magnification ratio, which is a different magnification ratio from the first magnification ratio, by picking up the specimen image.

摘要翻译： 图像拾取单元通过拾取由显微镜产生的样本的观察图像来获得样本图像。 安装状态信息获取单元获取表示插入到显微镜的观察光路中的光学构件的安装状态的安装状态信息。 曝光条件设定部根据摄像部拍摄观察图像，根据获取了标本图像的图像拍摄部所使用的安装状态信息，设定第二放大率的样本图像时所使用的曝光条件 通过拾取观察图像以第一放大倍率，并且基于当图像拍摄单元获得与第一放大率不同的倍率的第二倍率的样本图像时要使用的安装状态信息， 通过拾取标本图像。

公开(公告)号：US08253789B2

公开(公告)日：2012-08-28

申请号：US12702965

申请日：2010-02-09

申请人： Shinichiro Aizaki ,  Junzo Sakurai ,  Jitsunari Kojima

发明人： Shinichiro Aizaki ,  Junzo Sakurai ,  Jitsunari Kojima

IPC分类号： H04N9/47

CPC分类号： G02B21/365 ,  H04N1/401 ,  H04N1/409

摘要： In a correction data storing unit of a digital camera which captures a microscopic image, image data of a light image without a sample, image data obtained by using a filter for removing a defective portion for the light image without a sample, image data where a region without being corrected (or a region being corrected) is set in the light image without the sample, and shading correction data calculated from image data obtained by setting a mask region where data after being corrected is set to 0 are stored. An operator obtains, captures, records, and stores an observation image satisfactory for great-looking by using arbitrary shading correction data. In this way, a captured image satisfactory for great-looking is obtained by making a suitable shading correction according to a shading characteristic, which is caused by an optical system.

摘要翻译： 在拍摄微观图像的数字照相机的校正数据存储单元中，没有样本的光图像的图像数据，通过使用用于去除没有样本的光图像的缺陷部分的滤波器获得的图像数据，其中 没有校正的区域（或正在校正的区域）被设置在没有采样的光图像中，并且存储由将通过设置被校正后的数据设置为0的掩模区域而获得的图像数据计算出的阴影校正数据。 操作者通过使用任意阴影校正数据获得，捕获，记录和存储令人满意的观察图像。 以这种方式，通过根据由光学系统引起的阴影特性进行合适的阴影校正来获得令人满意的捕获图像。

公开(公告)号：US20050046905A1

公开(公告)日：2005-03-03

申请号：US10924594

申请日：2004-08-23

申请人： Shinichiro Aizaki ,  Junzo Sakurai ,  Jitsunari Kojima

发明人： Shinichiro Aizaki ,  Junzo Sakurai ,  Jitsunari Kojima

IPC分类号： G02B21/36 ,  G06T1/00 ,  H04N1/00 ,  H04N1/19 ,  H04N1/23 ,  H04N1/401 ,  H04N1/407 ,  H04N1/409 ,  H04N5/16 ,  H04N5/232 ,  H04N101/00

CPC分类号： G02B21/365 ,  H04N1/401 ,  H04N1/409

摘要： In a correction data storing unit of a digital camera which captures a microscopic image, image data of a light image without a sample, image data obtained by using a filter for removing a defective portion for the light image without a sample, image data where a region without being corrected (or a region being corrected) is set in the light image without the sample, and shading correction data calculated from image data obtained by setting a mask region where data after being corrected is set to 0 are stored. An operator obtains, captures, records, and stores an observation image satisfactory for great-looking by using arbitrary shading correction data. In this way, a captured image satisfactory for great-looking is obtained by making a suitable shading correction according to a shading characteristic, which is caused by an optical system.

摘要翻译： 在拍摄微观图像的数字照相机的校正数据存储单元中，没有样本的光图像的图像数据，通过使用用于去除没有样本的光图像的缺陷部分的滤波器获得的图像数据，其中 没有校正的区域（或正在校正的区域）被设置在没有采样的光图像中，并且存储由将通过设置被校正后的数据设置为0的掩模区域而获得的图像数据计算出的阴影校正数据。 操作者通过使用任意阴影校正数据获得，捕获，记录和存储令人满意的观察图像。 以这种方式，通过根据由光学系统引起的阴影特性进行合适的阴影校正来获得令人满意的捕获图像。

公开(公告)号：US07653300B2

公开(公告)日：2010-01-26

申请号：US11376232

申请日：2006-03-16

申请人： Koji Fujiyoshi ,  Jitsunari Kojima

发明人： Koji Fujiyoshi ,  Jitsunari Kojima

IPC分类号： G03B17/00 ,  G03B29/00 ,  H04N7/18

CPC分类号： G03B15/00 ,  G02B21/367 ,  G03B7/093 ,  G03B7/28 ,  G03B17/40 ,  H04N5/772 ,  H04N9/7921

摘要： An image recording apparatus for a microscope having a still camera function and/or a video photography function is disclosed. Automatic exposure (AE) adjustment is performed at appropriate time intervals in the photographic period so as to obtain sample images of roughly uniform brightness. Also, image data and data of plural photographic conditions are recorded in a single photographic session by setting up an AE adjustment time (Tae) and an exposure time (Texp) so as not to exceed a photographic interval (Tint) that is constant.

摘要翻译： 公开了一种具有静态相机功能和/或视频拍摄功能的显微镜的图像记录装置。 在摄影期间以适当的时间间隔进行自动曝光（AE）调整，以获得大致均匀亮度的样本图像。 此外，通过设置AE调整时间（Tae）和曝光时间（Texp），将图像数据和多个拍摄条件的数据记录在单次拍摄会话中，以便不超过恒定的拍摄间隔（Tint）。

公开(公告)号：US06505004B2

公开(公告)日：2003-01-07

申请号：US10085532

申请日：2002-02-27

申请人： Jitsunari Kojima ,  Kazuhiko Tsubota ,  Keiichi Iizuka ,  Tetsuo Tatsuda ,  Ri Sei ,  Tomohiro Uchida

发明人： Jitsunari Kojima ,  Kazuhiko Tsubota ,  Keiichi Iizuka ,  Tetsuo Tatsuda ,  Ri Sei ,  Tomohiro Uchida

IPC分类号： G02B2136

CPC分类号： G03B7/08

摘要： A photometric apparatus for a microscope comprises a light-reception element having a plurality of concentrically arranged photometric measurement areas, the light-reception element receiving observation light from the microscope and measuring a brightness of an observation image of the observation light, a calculation circuit for calculating an exposure time necessary for photographing the observation image, on the basis of a photometric measurement value obtained from at least one of the photometric measurement areas of the light-reception element, and a control circuit for performing an exposure operation on the basis of the exposure time calculated by the calculation circuit.