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公开(公告)号：US09273026B2
公开(公告)日：2016-03-01
申请号：US14685926
申请日：2015-04-14
申请人： Yves Auberson , Mark Gary Bock , Dario Braga , Marco Curzi , Stephanie Kay Dodd , Stefano Luca Giaffreda , Hayang Jiang , Piotr Karpinski , Thomas J. Troxler , Tie-Lin Wang , Xiaoyang Wang , Xuechun Zhang
发明人： Yves Auberson , Mark Gary Bock , Dario Braga , Marco Curzi , Stephanie Kay Dodd , Stefano Luca Giaffreda , Hayang Jiang , Piotr Karpinski , Thomas J. Troxler , Tie-Lin Wang , Xiaoyang Wang , Xuechun Zhang
IPC分类号： A61K31/501 , C07D401/04 , A61K31/496 , C07C57/15 , C07C59/265 , C07D403/04
CPC分类号： C07D401/04 , A61K31/496 , A61K31/501 , C07B2200/13 , C07C57/15 , C07C59/265 , C07D403/04
摘要： The invention relates to compound of the formula I or a salt thereof, wherein the substituents are as defined in the specification; to its preparation, to its use as medicament and to medicaments comprising it.
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公开(公告)号：US09624192B2
公开(公告)日：2017-04-18
申请号：US15049739
申请日：2016-02-22
申请人： Yves Auberson , Mark Gary Bock , Dario Braga , Marco Curzi , Stephanie Kay Dodd , Stefano Luca Giaffreda , Haiyang Jiang , Piotr Karpinski , Thomas J. Troxler , Tie-Lin Wang , Xiaoyang Wang , Xuechun Zhang
发明人： Yves Auberson , Mark Gary Bock , Dario Braga , Marco Curzi , Stephanie Kay Dodd , Stefano Luca Giaffreda , Haiyang Jiang , Piotr Karpinski , Thomas J. Troxler , Tie-Lin Wang , Xiaoyang Wang , Xuechun Zhang
IPC分类号： A61K31/501 , C07D401/04 , A61K31/496 , C07C57/15 , C07C59/265 , C07D403/04
CPC分类号： C07D401/04 , A61K31/496 , A61K31/501 , C07B2200/13 , C07C57/15 , C07C59/265 , C07D403/04
摘要： The invention relates to compound of the formula I or a salt thereof, wherein the substituents are as defined in the specification; to its preparation, to its use as medicament and to medicaments comprising it.
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公开(公告)号：US09034874B2
公开(公告)日：2015-05-19
申请号：US13944354
申请日：2013-07-17
申请人： Yves Auberson , Mark Gary Bock , Dario Braga , Marco Curzi , Stephanie Kay Dodd , Stefano Luca Giaffreda , Haiyang Jiang , Piotr Karpinski , Thomas J. Troxler , Tielin Wang , Xiaoyang Wang , Xuechun Zhang
发明人： Yves Auberson , Mark Gary Bock , Dario Braga , Marco Curzi , Stephanie Kay Dodd , Stefano Luca Giaffreda , Haiyang Jiang , Piotr Karpinski , Thomas J. Troxler , Tielin Wang , Xiaoyang Wang , Xuechun Zhang
IPC分类号： A61K31/496 , A61K31/501 , C07D401/04 , C07D403/04 , C07C57/15 , C07C59/265
CPC分类号： C07D401/04 , A61K31/496 , A61K31/501 , C07B2200/13 , C07C57/15 , C07C59/265 , C07D403/04
摘要： The invention relates to compound of the formula I or a salt thereof, wherein the substituents are as defined in the specification; to its preparation, to its use as medicament and to medicaments comprising it.
摘要翻译： 本发明涉及式I化合物或其盐，其中取代基如说明书中所定义; 作为其制备，用作药物和包含它的药物。
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公开(公告)号：US20140163036A1
公开(公告)日：2014-06-12
申请号：US13944354
申请日：2013-07-17
申请人： Yves AUBERSON , Mark Gary Bock , Dario Braga , Marco Curzi , Stephanie Kay Dodd , Stefano Luca Giaffreda , Haiyang Jiang , Piotr Karpinski , Thomas J. Troxler , Tielin Wang , Xiaoyang Wang , Xuechun Zhang
发明人： Yves AUBERSON , Mark Gary Bock , Dario Braga , Marco Curzi , Stephanie Kay Dodd , Stefano Luca Giaffreda , Haiyang Jiang , Piotr Karpinski , Thomas J. Troxler , Tielin Wang , Xiaoyang Wang , Xuechun Zhang
IPC分类号： C07D401/04 , C07C57/15 , C07C59/265 , A61K31/501 , A61K31/496
CPC分类号： C07D401/04 , A61K31/496 , A61K31/501 , C07B2200/13 , C07C57/15 , C07C59/265 , C07D403/04
摘要： The invention relates to compound of the formula I or a salt thereof, wherein the substituents are as defined in the specification; to its preparation, to its use as medicament and to medicaments comprising it.
摘要翻译： 本发明涉及式I化合物或其盐，其中取代基如说明书中所定义; 作为其制备，用作药物和包含它的药物。
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公开(公告)号：US20110009637A1
公开(公告)日：2011-01-13
申请号：US12702573
申请日：2010-02-09
申请人： Dario Braga , Stefano Luca Giaffreda , Marco Curzi
发明人： Dario Braga , Stefano Luca Giaffreda , Marco Curzi
IPC分类号： C07D401/12 , C30B7/06
CPC分类号： C07D401/12 , C30B7/06 , C30B29/54
摘要： The present invention relates to crystals of the Active Pharmaceutical Ingredient (API) Dexlansoprazole, including methods of making the crystals, pharmaceutical compositions comprising the crystals, and methods of treating a patient with the crystals.
摘要翻译： 本发明涉及活性药物成分（API）德兰索拉唑的晶体，包括制备晶体的方法，包含晶体的药物组合物和用晶体治疗患者的方法。
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公开(公告)号：US08673978B2
公开(公告)日：2014-03-18
申请号：US13078039
申请日：2011-04-01
IPC分类号： A61K31/192 , A61P25/28 , C07C61/40
CPC分类号： A61K31/192 , A61K9/0053 , C07B2200/13 , C07C61/40 , C07C229/26 , C07C279/14 , C07C2601/02
摘要： Novel polymorphic forms and salts of 1-(3′,4′-dichloro-2-fluorobiphenyl-4-yl)cyclopropanecarboxylic acid are useful for the prevention or treatment of Alzheimer's Disease.
摘要翻译： 1-（3'，4'-二氯-2-氟联苯-4-基）环丙烷羧酸的新型多晶型物和盐可用于预防或治疗阿尔茨海默氏病。
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公开(公告)号：US20110245346A1
公开(公告)日：2011-10-06
申请号：US13078039
申请日：2011-04-01
IPC分类号： A61K31/192 , C07C61/40 , A61P25/28
CPC分类号： A61K31/192 , A61K9/0053 , C07B2200/13 , C07C61/40 , C07C229/26 , C07C279/14 , C07C2601/02
摘要： Novel polymorphic forms and salts of 1-(3′,4′-dichloro-2-fluorobiphenyl-4-yl)cyclopropanecarboxylic acid are useful for the prevention or treatment of Alzheimer's Disease.
摘要翻译： 1-（3'，4'-二氯-2-氟联苯-4-基）环丙烷羧酸的新型多晶型物和盐可用于预防或治疗阿尔茨海默病。
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