公开(公告)号：US20240173462A1

公开(公告)日：2024-05-30

申请号：US18515201

申请日：2023-11-20

Applicant: Zhengzhou University

Inventor： Shaokang GUAN ,  Zhaoqi ZHANG ,  Jingan LI ,  Shijie ZHU ,  Liguo WANG ,  Peiduo TONG ,  Yahui WANG

IPC: A61L31/08

CPC classification number: A61L31/088 ,  A61L2420/02 ,  A61L2420/06

Abstract: A method for preparing a poly(thioctic acid)-copper coating (poly(TA-Cu)) on a surface of a cardiovascular stent material includes: grinding a cardiovascular stent material with sandpaper until the surface of the cardiovascular stent material is flat and smooth, rinsing the cardiovascular stent material with deionized water and anhydrous ethanol in sequence, and drying the cardiovascular stent material to obtain a pre-treated cardiovascular stent material; dissolving thioctic acid in an alcoholic solvent, adding anhydrous copper chloride to a mixed solution of thioctic acid and the alcoholic solvent, stirring the mixed solution, to yield a precursor solution; treating the pre-treated cardiovascular stent material with the precursor solution, and drying, thus forming a poly(thioctic acid)-copper coating on the surface of the pre-treated cardiovascular stent material. The concentration of thioctic acid in the alcoholic solvent is 0.1-0.3 g/mL, and the molar ratio of anhydrous copper chloride to thioctic acid monomer is 1:100-5000.

公开(公告)号：US20180305835A1

公开(公告)日：2018-10-25

申请号：US16022671

申请日：2018-06-28

Applicant: Zhengzhou University

Inventor： Shaokang GUAN ,  Di MEI ,  Yashan FENG ,  Shijie ZHU ,  Jun WANG ,  Liguo WANG ,  Yanhua WANG

IPC: C25D9/12 ,  A61L27/32 ,  A61L27/58

CPC classification number: C25D9/12 ,  A61L27/32 ,  A61L27/58 ,  A61L2430/02

Abstract: A method including: employing pure magnesium or a magnesium alloy as a substrate material, and sanding and cleaning the substrate material; preparing an electrolyte including 0.8-8 mmol/L of Zn2+, 30-50 mmol/L of Ca°, 15-35 mmol/L of H2PO4−, 0-0.5 mol/L of NaNO3, and 0-0.05 mmol/L of a magnesium ion complexing agent; employing the substrate material as a cathode, a graphite flake as an anode, heating the electrolyte to a temperature of between 60 and 90° C., and synchronously immersing the cathode and the anode into the electrolyte; and implementing an electrochemical deposition method in the electrolyte for between 20 and 60 min.