利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

22 条记录 (耗时 0.038 秒)

    Micturitional assist device
    1.
    发明授权
    Micturitional assist device 失效
    MICTURITIONAL ASSIST设备

    公开(公告)号：US5199430A

    公开(公告)日：1993-04-06

    申请号：US667523

    申请日：1991-03-11

    申请人： Zi-Ping Fang ,  J. Thomas Mortimer ,  Graham H. Creasey

    发明人： Zi-Ping Fang ,  J. Thomas Mortimer ,  Graham H. Creasey

    IPC分类号： A61N1/05

    CPC分类号： A61N1/36007 ,  A61N1/0556

    摘要： Cuff electrodes (40a, 40b) are surgically implanted around S.sub.3 sacral ventral root nerve trunks (16a, 16b). The sacral ventral roots have smaller diameter nerve fibers (20a, 20b) which convey action potentials to cause detrusor activation to contract the bladder (10) and larger diameter nerve fibers (18a, 18 b) which carry action potentials for causing contraction of a urethral sphincter (12) to block the flow of urine from the bladder. A current source (50) causes current pulses (52) between such electrical contacts (46, 48) and a central electrical contact (44). The current pulses have an appropriate amplitude and waveform to initiate action potentials adjacent the central contact and to block the propagation of action potentials adjacent the end electrodes along the larger diameter nerve fibers (which have fewer nodes between the contacts) but not the smaller diameter nerve fibers (which have more nodes between the electrodes). In this manner, action potentials are electrically excited to propagate at least downstream on the smaller diameter nerve fibers causing contraction of the bladder. Concurrently, blocking action potentials are allowed to propagate upstream on at least the larger diameter nerve fibers, collision blocking naturally occurring action potentials propagating downstream. The transmission of action potentials downstream on the larger diameter nerve fibers is blocked by the current pulses allowing the urinary sphincter to relax.

    摘要翻译： 袖带电极（40a，40b）通过外科手术植入S3骶神经根神经干（16a，16b）周围。 骶腹根具有较小直径的神经纤维（20a，20b），其传达动作电位以引起逼尿肌激活以收缩膀胱（10）和较大直径的神经纤维（18a，18b），其具有引起尿道收缩的动作电位 括约肌（12）阻止尿液从膀胱流出。 电流源（50）在这种电触头（46,48）和中心电触点（44）之间引起电流脉冲（52）。 电流脉冲具有适当的幅度和波形，以引发邻近中心触点的动作电位，并阻止沿着较大直径的神经纤维（其中在触点之间具有较少节点）的端电极附近的动作电位的传播，而不是较小直径的神经 光纤（电极之间具有更多的节点）。 以这种方式，动作电位被电激励，至少在较小直径的神经纤维的下游传播，引起膀胱收缩。 同时，阻塞动作电位允许在至少较大直径的神经纤维上游传播，碰撞阻止在下游传播的自然发生的动作电位。 在较大直径的神经纤维下游的动作电位的传递被允许尿括约肌松弛的电流脉冲阻止。

    Systems and methods for producing asynchronous neural responses to treat pain and/or other patient conditions
    9.
    发明授权
    Systems and methods for producing asynchronous neural responses to treat pain and/or other patient conditions 有权
    用于产生用于治疗疼痛和/或其他患者病症的异步神经反应的系统和方法

    公开(公告)号：US08255057B2

    公开(公告)日：2012-08-28

    申请号：US12362244

    申请日：2009-01-29

    申请人： Zi-Ping Fang ,  Anthony V. Caparso ,  Andre B. Walker

    发明人： Zi-Ping Fang ,  Anthony V. Caparso ,  Andre B. Walker

    IPC分类号： A61N1/00

    CPC分类号： A61N1/36171 ,  A61N1/0551 ,  A61N1/36071 ,  A61N1/37247

    摘要： Systems and methods for producing asynchronous neural responses to treat pain and/or other patient conditions are disclosed. A method in accordance with a particular embodiment includes selecting a target stimulation frequency that is above a threshold frequency, with the threshold frequency corresponding to a refractory period for neurons of a target sensory neural population. The method can further include producing a patient sensation of paresthesia by directing an electrical signal to multiple sensory neurons of the target sensory neural population at the stimulation frequency, with individual neurons of the sensory neural population completing corresponding individual refractory periods at different times, resulting in an asynchronous sensory neuron response to the electrical signal.

    摘要翻译： 公开了用于产生用于治疗疼痛和/或其他患者状况的异步神经反应的系统和方法。 根据特定实施例的方法包括选择阈值频率以上的目标刺激频率，阈值频率对应于目标感觉神经群体的神经元的不应期。 该方法可以进一步包括通过在刺激频率下将电信号引导到目标感觉神经群体的多个感觉神经元来产生感觉异常感觉，感觉神经群体的个体神经元在不同时间完成相应的单个不应期，导致 对电信号的异步感觉神经元响应。

    Treatment of shoulder dysfunction using a percutaneous intramuscular stimulation system
    10.
    发明授权
    Treatment of shoulder dysfunction using a percutaneous intramuscular stimulation system 有权
    使用经皮肌肉内刺激系统治疗肩功能障碍

    公开(公告)号：US08249713B2

    公开(公告)日：2012-08-21

    申请号：US11982789

    申请日：2007-11-05

    申请人： Zi-Ping Fang ,  Maria E. Walker

    发明人： Zi-Ping Fang ,  Maria E. Walker

    IPC分类号： A61N1/05

    CPC分类号： A61N1/36003 ,  A61N1/36017

    摘要： A method of treating shoulder dysfunction involves the use of a percutaneous, intramuscular stimulation system. A plurality of intramuscular stimulation electrodes are implanted directly into select shoulder muscles of a patient who has suffered a disruption of the central nervous system such as a stroke, traumatic brain injury, spinal cord injury or cerebral palsy. An external microprocessor based multi-channel stimulation pulse train generator is used for generating select electrical stimulation pulse train signals. A plurality of insulated electrode leads percutaneously, electrically interconnect the plurality of intramuscular stimulation electrodes to the external stimulation pulse train generator, respectively. Stimulation pulse train parameters for each of the stimulation pulse train output channels are selected independently of the other channels. The shoulder is evaluated for subluxation in more than one dimension. More than one muscle or muscle group is simultaneously subjected to a pulse train dosage. Preferably, the at least two dosages are delivered asynchronously to two muscle groups comprising the supraspinatus in combination with the middle deltoid, and the trapezious in combination with the posterior deltoid.

    摘要翻译： 治疗肩功能障碍的方法涉及使用经皮肌肉内刺激系统。 将多个肌内刺激电极直接植入患有中枢神经系统如脑卒中，创伤性脑损伤，脊髓损伤或脑瘫的中断的患者的选择的肩部肌肉。 用于产生选择电刺激脉冲串信号的外部基于微处理器的多通道刺激脉冲串发生器被使用。 多个绝缘电极引线经皮地将多个肌内刺激电极分别电连接到外部刺激脉冲串发生器。 每个刺激脉冲串输出通道的刺激脉冲序列参数独立于其它通道进行选择。 评估肩膀在多于一个维度的半脱位。 多个肌肉组或肌肉组同时进行脉搏训练。 优选地，将至少两种剂量异步地递送到包括上棘的两个肌肉组合，与中间三角肌组合，并且与后三角肌组合呈梯形。