公开(公告)号：US20100168767A1

公开(公告)日：2010-07-01

申请号：US12492779

申请日：2009-06-26

申请人： Zia Yassinzadeh ,  Delfin Pelayo

发明人： Zia Yassinzadeh ,  Delfin Pelayo

IPC分类号： A61B17/10 ,  A61B17/08

CPC分类号： A61B17/0057 ,  A61B2017/00004 ,  A61B2017/00623 ,  A61B2017/00654 ,  A61B2017/00893 ,  A61B2017/00898 ,  A61B2017/22067 ,  A61B2090/3966

摘要： Apparatus for sealing a vascular wall penetration disposed at the end of the tissue tract comprises a shaft, an occlusion element, a hemostatic implant, and a protective sleeve. The apparatus is deployed through the tissue tract with the occlusion element temporarily occluding the vascular wall penetration and inhibiting backbleeding therethrough. The hemostatic implant, which will typically be a biodegradable polymer such as collagen carrying an anti-proliferative agent or coagulation promoter, will then be deployed from the sealing apparatus and left in place to enhance closure of the vascular wall penetration with minimum scarring. The implant may be radiopaque to allow observation before release.

摘要翻译： 用于密封设置在组织管道末端处的血管壁穿透物的装置包括轴，闭塞元件，止血植入物和保护套管。 该装置通过组织道展开，闭塞元件暂时阻塞血管壁穿透并阻止其通过其反渗透。 通常是可生物降解的聚合物（例如携带抗增殖剂或凝​​血促进剂的胶原）的止血植入物将从密封装置展开并留在原位以增强血管壁穿透的封闭，同时具有最小的瘢痕形成。 植入物可以是不透射线的，以便在释放之前观察。

公开(公告)号：US20050267522A1

公开(公告)日：2005-12-01

申请号：US10974008

申请日：2004-10-25

申请人： Zia Yassinzadeh ,  Delfin Pelayo

发明人： Zia Yassinzadeh ,  Delfin Pelayo

IPC分类号： A61B17/00 ,  A61B17/08 ,  A61F2/958

CPC分类号： A61B17/0057 ,  A61B2017/00659 ,  A61B2017/00986 ,  A61B2090/0807

摘要： The present invention advantageously provides self-tensioning occlusion devices, systems, and methods for percutaneous access and closure of vascular puncture sites. One device comprises a catheter body, an occlusion member, and a tensioning member. The occlusion member, such an expansible member, is disposed on a distal end of the body. The tensioning member, such as a spring or coil, is slidably disposed over the body and proximal the expansion member. Generally, during application, the tensioning member will be deployed against subcutaneous tissue so as to apply tension to the expansible member against the puncture site. The substantial hold once the tension is applied is then provided by external means, such as an anchoring clip.

摘要翻译： 本发明有利地提供了用于经皮通路和闭合血管穿刺部位的自张紧闭塞装置，系统和方法。 一个装置包括导管主体，遮挡构件和张紧构件。 这种可膨胀构件的遮挡构件设置在主体的远端上。 张紧构件，例如弹簧或线圈，可滑动地设置在身体上并且靠近扩张构件。 通常，在施用期间，张紧构件将被展开抵靠皮下组织，以便可靠地抵靠穿刺部位向可膨胀构件施加张力。 一旦施加张力，实质上的保持力然后由外部装置（例如锚固夹）提供。

公开(公告)号：US07993366B2

公开(公告)日：2011-08-09

申请号：US10974008

申请日：2004-10-25

申请人： Zia Yassinzadeh ,  Delfin Pelayo

发明人： Zia Yassinzadeh ,  Delfin Pelayo

IPC分类号： A61B17/08

CPC分类号： A61B17/0057 ,  A61B2017/00659 ,  A61B2017/00986 ,  A61B2090/0807

摘要： The present invention advantageously provides self-tensioning occlusion devices, systems, and methods for percutaneous access and closure of vascular puncture sites. One device includes a catheter body, an occlusion member, and a tensioning member. The occlusion member, such an expansible member, is disposed on a distal end of the body. The tensioning member, such as a spring or coil, is slidably disposed over the body and proximal the expansion member. Generally, during application, the tensioning member will be deployed against subcutaneous tissue so as to apply tension to the expansible member against the puncture site. The substantial hold once the tension is applied is then provided by an external element, such as an anchoring clip.

摘要翻译： 本发明有利地提供了用于经皮通路和闭合血管穿刺部位的自张紧闭塞装置，系统和方法。 一个装置包括导管主体，遮挡构件和张紧构件。 这种可膨胀构件的遮挡构件设置在主体的远端上。 张紧构件，例如弹簧或线圈，可滑动地设置在身体上并且靠近扩张构件。 通常，在施用期间，张紧构件将被展开抵靠皮下组织，以便可靠地抵靠穿刺部位向可膨胀构件施加张力。 一旦张力被施加，实质上的保持力就由诸如锚固夹的外部元件提供。

公开(公告)号：US20120209321A1

公开(公告)日：2012-08-16

申请号：US13452656

申请日：2012-04-20

申请人： Zia Yassinzadeh ,  Delfin Pelayo

发明人： Zia Yassinzadeh ,  Delfin Pelayo

IPC分类号： A61B17/08

CPC分类号： A61B17/0057 ,  A61B90/39 ,  A61B2017/00004 ,  A61B2017/00623 ,  A61B2017/00654 ,  A61B2017/00893 ,  A61B2017/00898 ,  A61B2017/22067 ,  A61B2090/3966

摘要： Apparatus for sealing a vascular wall penetration disposed at the end of the tissue tract comprises a shaft, an occlusion element, a hemostatic implant, and a protective sleeve. The apparatus is deployed through the tissue tract with the occlusion element temporarily occluding the vascular wall penetration and inhibiting backbleeding therethrough. The hemostatic implant, which will typically be a biodegradable polymer such as collagen carrying an anti-proliferative agent or coagulation promoter, will then be deployed from the sealing apparatus and left in place to enhance closure of the vascular wall penetration with minimum scarring. The implant may be radiopaque to allow observation before release.

摘要翻译： 用于密封设置在组织管道末端处的血管壁穿透物的装置包括轴，闭塞元件，止血植入物和保护套管。 该装置通过组织道展开，闭塞元件暂时阻塞血管壁穿透并阻止其通过其反渗透。 通常是可生物降解的聚合物（例如携带抗增殖剂或凝​​血促进剂的胶原）的止血植入物将从密封装置展开并留在原位以增强血管壁穿透的封闭，同时具有最小的瘢痕形成。 植入物可以是不透射线的，以便在释放之前观察。

公开(公告)号：US08911472B2

公开(公告)日：2014-12-16

申请号：US13452656

申请日：2012-04-20

申请人： Zia Yassinzadeh ,  Delfin Pelayo

发明人： Zia Yassinzadeh ,  Delfin Pelayo

IPC分类号： A61B17/08 ,  A61D1/00 ,  A61B17/00 ,  A61B19/00 ,  A61B17/22

CPC分类号： A61B17/0057 ,  A61B90/39 ,  A61B2017/00004 ,  A61B2017/00623 ,  A61B2017/00654 ,  A61B2017/00893 ,  A61B2017/00898 ,  A61B2017/22067 ,  A61B2090/3966

摘要： Apparatus for sealing a vascular wall penetration disposed at the end of the tissue tract comprises a shaft, an occlusion element, a hemostatic implant, and a protective sleeve. The apparatus is deployed through the tissue tract with the occlusion element temporarily occluding the vascular wall penetration and inhibiting backbleeding therethrough. The hemostatic implant, which will typically be a biodegradable polymer such as collagen carrying an anti-proliferative agent or coagulation promoter, will then be deployed from the sealing apparatus and left in place to enhance closure of the vascular wall penetration with minimum scarring. The implant may be radiopaque to allow observation before release.

摘要翻译： 用于密封设置在组织管道末端处的血管壁穿透物的装置包括轴，闭塞元件，止血植入物和保护套管。 该装置通过组织道展开，闭塞元件暂时阻塞血管壁穿透并阻止其通过其反渗透。 通常是可生物降解的聚合物（例如携带抗增殖剂或凝​​血促进剂的胶原）的止血植入物将从密封装置展开并留在原位以增强血管壁穿透的封闭，同时具有最小的瘢痕形成。 植入物可以是不透射线的，以便在释放之前观察。