-
公开(公告)号：US08951791B2
公开(公告)日：2015-02-10
申请号：US14093833
申请日：2013-12-02
申请人： iBio, Inc.
CPC分类号： C12N15/8203 , C07K14/61 , C07K14/62 , C12N7/00 , C12N15/8257 , C12N2770/00043 , C12P21/02
摘要： The present invention provides trans-complementation systems for expressing gene products in plants. In general, the invention provides systems including a carrier vector and a producer vector, both based on plant viruses. The producer vector is defective for at least one function needed for successful systemic infection of a plant, e.g., replication, cell-to-cell movement, or long distance movement. The carrier vector supplies the missing function in trans. Certain producer vectors lack a functional coat protein coding sequence, in which case the corresponding producer vector supplies coat protein in trans. The invention also provides novel plant viral vectors and methods of use, e.g., to produce polypeptides or active RNAs in plants.
-
公开(公告)号：US09765349B2
公开(公告)日：2017-09-19
申请号：US15398388
申请日：2017-01-04
申请人： iBio, Inc.
CPC分类号： C12N15/8203 , C07K14/61 , C07K14/62 , C12N7/00 , C12N15/8257 , C12N2770/00043 , C12P21/02
摘要： The present invention provides trans-complementation systems for expressing gene products in plants. In general, the invention provides systems including a carrier vector and a producer vector, both based on plant viruses. The producer vector is defective for at least one function needed for successful systemic infection of a plant, e.g., replication, cell-to-cell movement, or long distance movement. The carrier vector supplies the missing function in trans. Certain producer vectors lack a functional coat protein coding sequence, in which case the corresponding producer vector supplies coat protein in trans. The invention also provides novel plant viral vectors and methods of use, e.g., to produce polypeptides or active RNAs in plants.
-
公开(公告)号：US09551001B2
公开(公告)日：2017-01-24
申请号：US14602769
申请日：2015-01-22
申请人： iBio, Inc.
CPC分类号： C12N15/8203 , C07K14/61 , C07K14/62 , C12N7/00 , C12N15/8257 , C12N2770/00043 , C12P21/02
摘要： The present invention provides trans-complementation systems for expressing gene products in plants. In general, the invention provides systems including a carrier vector and a producer vector, both based on plant viruses. The producer vector is defective for at least one function needed for successful systemic infection of a plant, e.g., replication, cell-to-cell movement, or long distance movement. The carrier vector supplies the missing function in trans. Certain producer vectors lack a functional coat protein coding sequence, in which case the corresponding producer vector supplies coat protein in trans. The invention also provides novel plant viral vectors and methods of use, e.g., to produce polypeptides or active RNAs in plants.
摘要翻译： 本发明提供用于在植物中表达基因产物的反式互补系统。 通常，本发明提供了包括载体载体和生产者载体的系统，其都是基于植物病毒的。 生产者载体对于植物的成功的全身感染所需的至少一个功能是有缺陷的，例如复制，细胞到细胞运动或长距离运动。 载波向量以反向方式提供丢失的功能。 某些生产者载体缺乏功能外壳蛋白编码序列，在这种情况下，相应的生产者载体以反式提供外壳蛋白。 本发明还提供新的植物病毒载体和使用方法，例如在植物中产生多肽或活性RNA。
-
公开(公告)号：US20160060644A1
公开(公告)日：2016-03-03
申请号：US14602769
申请日：2015-01-22
申请人： iBio, Inc.
IPC分类号： C12N15/82
CPC分类号： C12N15/8203 , C07K14/61 , C07K14/62 , C12N7/00 , C12N15/8257 , C12N2770/00043 , C12P21/02
摘要： The present invention provides trans-complementation systems for expressing gene products in plants. In general, the invention provides systems including a carrier vector and a producer vector, both based on plant viruses. The producer vector is defective for at least one function needed for successful systemic infection of a plant, e.g., replication, cell-to-cell movement, or long distance movement. The carrier vector supplies the missing function in trans. Certain producer vectors lack a functional coat protein coding sequence, in which case the corresponding producer vector supplies coat protein in trans. The invention also provides novel plant viral vectors and methods of use, e.g., to produce polypeptides or active RNAs in plants.
摘要翻译： 本发明提供用于在植物中表达基因产物的反式互补系统。 通常，本发明提供了包括载体载体和生产者载体的系统，其都是基于植物病毒的。 生产者载体对于植物的成功的全身感染所需的至少一个功能是有缺陷的，例如复制，细胞到细胞运动或长距离运动。 载波向量以反向方式提供丢失的功能。 某些生产者载体缺乏功能外壳蛋白编码序列，在这种情况下，相应的生产者载体以反式提供外壳蛋白。 本发明还提供新的植物病毒载体和使用方法，例如在植物中产生多肽或活性RNA。
-
公开(公告)号：US20170121721A1
公开(公告)日：2017-05-04
申请号：US15398388
申请日：2017-01-04
申请人： iBio, Inc.
CPC分类号： C12N15/8203 , C07K14/61 , C07K14/62 , C12N7/00 , C12N15/8257 , C12N2770/00043 , C12P21/02
摘要： The present invention provides trans-complementation systems for expressing gene products in plants. In general, the invention provides systems including a carrier vector and a producer vector, both based on plant viruses. The producer vector is defective for at least one function needed for successful systemic infection of a plant, e.g., replication, cell-to-cell movement, or long distance movement. The carrier vector supplies the missing function in trans. Certain producer vectors lack a functional coat protein coding sequence, in which case the corresponding producer vector supplies coat protein in trans. The invention also provides novel plant viral vectors and methods of use, e.g., to produce polypeptides or active RNAs in plants.
-
公开(公告)号：US20140220674A1
公开(公告)日：2014-08-07
申请号：US14093833
申请日：2013-12-02
申请人： iBio, Inc.
IPC分类号： C12N15/82
CPC分类号： C12N15/8203 , C07K14/61 , C07K14/62 , C12N7/00 , C12N15/8257 , C12N2770/00043 , C12P21/02
摘要： The present invention provides trans-complementation systems for expressing gene products in plants. In general, the invention provides systems including a carrier vector and a producer vector, both based on plant viruses. The producer vector is defective for at least one function needed for successful systemic infection of a plant, e.g., replication, cell-to-cell movement, or long distance movement. The carrier vector supplies the missing function in trans. Certain producer vectors lack a functional coat protein coding sequence, in which case the corresponding producer vector supplies coat protein in trans. The invention also provides novel plant viral vectors and methods of use, e.g., to produce polypeptides or active RNAs in plants.
摘要翻译： 本发明提供用于在植物中表达基因产物的反式互补系统。 通常，本发明提供了包括载体载体和生产者载体的系统，其都是基于植物病毒的。 生产者载体对于植物的成功的全身感染所需的至少一个功能是有缺陷的，例如复制，细胞到细胞运动或长距离运动。 载波向量以反向方式提供丢失的功能。 某些生产者载体缺乏功能外壳蛋白编码序列，在这种情况下，相应的生产者载体以反式提供外壳蛋白。 本发明还提供新的植物病毒载体和使用方法，例如在植物中产生多肽或活性RNA。
-
-
-
-
-
搜索结果
6 条记录 (耗时 0.017 秒)
