公开(公告)号：US20190136310A1

公开(公告)日：2019-05-09

申请号：US16155729

申请日：2018-10-09

Applicant: uBiome, Inc.

Inventor： Zachary Apte ,  Jessica Richman ,  Daniel Almonacid ,  Eduardo Morales ,  Luis Leon ,  Sara W. Bird ,  Juan Ugalde

IPC: C12Q1/6869

Abstract: Embodiments of a method and/or system (e.g., for improved single molecule sequencing, etc.) can include preparing a set of unique molecular identifier (UMI)-based molecules associated with a set of target nucleic acid sequences; facilitating generation of (e.g., generating, etc.) a set of tagged nucleic acid molecules based on the set of UMI-based molecules and a set of nucleic acid molecules corresponding to (e.g., including, etc.) the set of target nucleic acid sequences; and/or facilitating (e.g., performing, etc.) single molecule sequencing with the set of tagged nucleic acid molecules.

公开(公告)号：US20170308669A1

公开(公告)日：2017-10-26

申请号：US15649497

申请日：2017-07-13

Applicant: uBiome, Inc.

Inventor： Zachary Apte ,  Jessica Richman ,  Daniel Almonacid ,  Inti Pedroso ,  Juan Ugalde ,  Rodrigo Ortiz

IPC: G06F19/00 ,  G06F19/28

CPC classification number: G06F19/3418 ,  C12Q1/6883 ,  C12Q1/689 ,  C12Q2600/106 ,  C12Q2600/118 ,  C12Q2600/156 ,  G06F19/30 ,  G16B20/00 ,  G16B30/10 ,  G16B40/20 ,  G16B50/00 ,  G16B50/20 ,  G16B50/30 ,  G16H10/40 ,  G16H20/10 ,  G16H20/40 ,  G16H40/63 ,  G16H40/67 ,  G16H50/20 ,  G16H50/50

Abstract: Embodiments of a method and system for microbial pharmacogenomics can include: a sample handling system operable to collect containers including biological samples from a set of users, the handling system including a sequencing system operable to determine microorganism sequences from the biological samples; a microbiome characterization system operable to: determine microbiome pharmacogenomics data based on the microorganism sequences, collect supplementary data associated with the antibiotics-associated condition for the set of users, and transform the supplementary data and features extracted from the microbiome pharmacogenomics data into a characterization model associated with the antibiotics-associated condition; and a treatment system operable to promote a treatment to the user for the antibiotics-associated condition based on characterizing user biological material with the characterization model in relation to the antibiotics-associated condition.

公开(公告)号：US20190019575A1

公开(公告)日：2019-01-17

申请号：US16124108

申请日：2018-09-06

Applicant: uBiome, Inc.

Inventor： Zachary Apte ,  Jessica Richman ,  Daniel Almonacid ,  Juan Ugalde ,  Patricia Vera-Wolf ,  Sandro Valenzuela

IPC: G16H20/10 ,  G06F19/28 ,  G16H10/60 ,  C12Q1/689

Abstract: Embodiments of a method and/or system (e.g., for nasal-related characterization) can include determining a microorganism dataset associated with a set of subjects; and/or performing a characterization process based on the microorganism dataset, where performing the characterization process can additionally or alternatively include performing a nasal-related characterization process, and/or determining one or more therapies, such as for one or more nasal-related conditions.