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    KITS FOR PREPARING A REACTIVE GRAFT MATERIAL AND INJECTING THE GRAFT MATERIAL INTO A PATIENT
    1.
    发明申请
    KITS FOR PREPARING A REACTIVE GRAFT MATERIAL AND INJECTING THE GRAFT MATERIAL INTO A PATIENT 有权

    公开(公告)号：US20210220514A1

    公开(公告)日：2021-07-22

    申请号：US17219763

    申请日：2021-03-31

    申请人： Agnovos Healthcare, LLC

    发明人： Jon P. Moseley ,  Jamie MacDougall ,  Katie Harrigan

    IPC分类号： A61L27/12 ,  C04B28/34 ,  A61L24/02 ,  A61L27/02 ,  A61L27/36 ,  A61L27/54 ,  A61L27/56 ,  A61L27/58 ,  A61L24/00 ,  C04B28/14 ,  A61L27/38

    摘要： Disclosed are kits for preparing a reactive graft material and injecting the graft material into a patient. Kits may include a first syringe containing a first powdered component and a second syringe containing a second powdered component that is reactive with the first powdered component when the first and second powdered components are dispersed in a diluent solution. The kits may further include a vial sealed by a septum and containing the diluent solution. A syringe connector may be included that has a connector at each end configured to make a fluidic connection to, respectively, the first syringe and the second syringe, and also comprises a passageway adapted to allow fluid to pass between the syringes when the syringes are both fluidically connected to the syringe connector. A vial adapter comprising a connector adapted for fluidically connecting to at least one of the first syringe and the second syringe, a passageway adapted to allow fluid to pass from the vial into a syringe fluidically connected to the connector of the vial adapter, and a spike in fluidic communication with the passageway of the vial adapter may be included. The spike is adapted for piercing the septum of the vial. Certain kits also contain one or more needles for delivery of the graft material to a site within a body of a patient.

    METHODS OF TREATING DEGENERATIVE BONE CONDITIONS
    4.
    发明申请
    METHODS OF TREATING DEGENERATIVE BONE CONDITIONS 审中-公开
    治疗骨质疏松症的方法

    公开(公告)号：US20170027591A1

    公开(公告)日：2017-02-02

    申请号：US15294954

    申请日：2016-10-17

    申请人： Agnovos Healthcare, LLC

    发明人： Olaf Schulz ,  James G. Howe ,  Rick Swaim ,  Bryan Huber ,  Joel Batts ,  David Harness ,  Ryan Belaney

    IPC分类号： A61B17/16 ,  A61B17/17 ,  A61M1/00

    摘要： A combination suction and irrigation device for a medical procedure. The device includes an elongated body having a proximal end and a distal end and defines an open channel that extends from the proximal end to the distal end. The open channel is open at both the proximal end and the distal end. A suction port is in communication with the open channel and is connectable to a source of suction. An irrigation port is in communication with the open channel and is connectable to a source of irrigation fluid. A valve selectively opens and closes the open channel to flow relative to the suction port and to the open proximal end, and to flow relative to the irrigation port.

    摘要翻译： 用于医疗程序的组合吸入和冲洗装置。 该装置包括具有近端和远端的细长主体，并且限定从近端延伸到远端的开口通道。 开放通道在近端和远端都是敞开的。 吸入口与开放通道连通，并且可连接到吸入源。 灌溉口与开放通道连通，可连接到冲洗流体源。 阀选择性地打开和关闭开放通道以相对于吸入口和开放的近端流动并相对于冲洗口流动。

    Composite bone graft substitute cement and articles produced therefrom
    6.
    发明授权
    Composite bone graft substitute cement and articles produced therefrom 有权
    复合骨移植替代水泥及其制品

    公开(公告)号：US09180224B2

    公开(公告)日：2015-11-10

    申请号：US12814033

    申请日：2010-06-11

    申请人： Jon P. Moseley ,  Michael E. Carroll ,  Jonathan D. McCanless

    发明人： Jon P. Moseley ,  Michael E. Carroll ,  Jonathan D. McCanless

    IPC分类号： A61L27/02 ,  A61L27/12 ,  A61L27/36 ,  A61L27/42 ,  A61L27/58

    CPC分类号： A61L27/427 ,  A61L27/025 ,  A61L27/12 ,  A61L27/365 ,  A61L27/58 ,  A61L2400/06 ,  A61L2430/02

    摘要： The invention provides a particulate composition adapted for forming a bone graft substitute cement upon mixing with an aqueous solution, including i) a calcium sulfate hemihydrate powder having a bimodal particle distribution and a median particle size of about 5 to about 20 microns, wherein the calcium sulfate hemihydrate is present at a concentration of at least about 70 weight percent based on the total weight of the particulate composition; ii) a monocalcium phosphate monohydrate powder; and iii) a β-tricalcium phosphate powder having a median particle size of less than about 20 microns. Bone graft substitute cements made therefrom, a bone graft substitute kit comprising the particulate composition, methods of making and using the particulate composition, and articles made from the bone graft substitute cement are also provided.

    摘要翻译： 本发明提供一种适于在与水溶液混合时形成骨移植物替代水泥的颗粒组合物，包括i）具有约5至约20微米的双峰颗粒分布和中值粒度的硫酸钙半水合物粉末，其中所述钙 硫酸盐半水合物以基于颗粒组合物的总重量的至少约70重量％的浓度存在; ii）一水合一磷酸钙粉末; 和iii）中值粒度小于约20微米的磷酸三钙粉末。 还提供了由其制成的骨移植替代物水泥，包含颗粒组合物的骨移植替代试剂盒，制备和使用颗粒组合物的方法，以及由骨移植物替代水泥制成的制品。

    Composite bone graft substitute cement and articles produced therefrom
    10.
    发明授权
    Composite bone graft substitute cement and articles produced therefrom 有权
    复合骨移植替代水泥及其制品

    公开(公告)号：US08685464B2

    公开(公告)日：2014-04-01

    申请号：US11624460

    申请日：2007-01-18

    申请人： Jon P. Moseley ,  Michael E. Carroll ,  Jonathan D. McCanless

    发明人： Jon P. Moseley ,  Michael E. Carroll ,  Jonathan D. McCanless

    IPC分类号： A61K33/42 ,  A61K9/00 ,  A61K9/14 ,  A61K33/04 ,  A61K33/06 ,  A61K35/32 ,  A61K38/18 ,  A61K47/12 ,  A61P19/00

    CPC分类号： A61L27/427 ,  A61L27/025 ,  A61L27/12 ,  A61L27/365 ,  A61L27/58 ,  A61L2400/06 ,  A61L2430/02

    摘要： The invention provides a particulate composition adapted for forming a bone graft substitute cement upon mixing with an aqueous solution, including i) a calcium sulfate hemihydrate powder having a bimodal particle distribution and a median particle size of about 5 to about 20 microns, wherein the calcium sulfate hemihydrate is present at a concentration of at least about 70 weight percent based on the total weight of the particulate composition; ii) a monocalcium phosphate monohydrate powder; and iii) a β-tricalcium phosphate powder having a median particle size of less than about 20 microns. Bone graft substitute cements made therefrom, a bone graft substitute kit comprising the particulate composition, methods of making and using the particulate composition, and articles made from the bone graft substitute cement are also provided.

    摘要翻译： 本发明提供一种适于在与水溶液混合时形成骨移植物替代水泥的颗粒组合物，包括i）具有约5至约20微米的双峰颗粒分布和中值粒度的硫酸钙半水合物粉末，其中所述钙 硫酸盐半水合物以基于颗粒组合物的总重量的至少约70重量％的浓度存在; ii）一水合一磷酸钙粉末; 和iii）中值粒度小于约20微米的磷酸三钙粉末。 还提供了由其制成的骨移植替代物水泥，包含颗粒组合物的骨移植替代试剂盒，制备和使用颗粒组合物的方法，以及由骨移植物替代水泥制成的制品。