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    CUVETTE FOR BODY FLUID ANALYSIS
    1.
    发明公开
    CUVETTE FOR BODY FLUID ANALYSIS 审中-公开

    公开(公告)号：US20240328925A1

    公开(公告)日：2024-10-03

    申请号：US18567950

    申请日：2022-12-20

    申请人： Hemocue AB

    发明人： Per NILSSON ,  Joakim PETTERSSON ,  Johan RAHNBOY

    IPC分类号： G01N21/07 ,  B01L3/00

    CPC分类号： G01N21/07 ,  B01L3/502 ,  B01L2200/0684 ,  B01L2400/0409

    摘要： Disclosed is cuvette for body fluid analysis. The cuvette comprising a sampling cavity comprising a fluid inlet, a sample analysis cavity, and a venting cavity being in fluid connection with the sampling cavity and the sample analysis cavity. The venting cavity has an outlet to the exterior of the cuvette. The cuvette is configured to transfer, when a centrifugal force is applied to the cuvette, a body fluid from the sampling cavity to the sample analysis cavity via the venting cavity. The sample analysis cavity is configured to provide a first capillary force, wherein the first capillary force is higher than a capillary force in the venting cavity. The sample analysis cavity is configured for separating and analyzing the body fluid sample.

    Enumeration of white blood cells
    2.
    发明授权
    Enumeration of white blood cells 有权
    计数白细胞

    公开(公告)号：US07521243B2

    公开(公告)日：2009-04-21

    申请号：US11102837

    申请日：2005-04-11

    申请人： Stellan Lindberg ,  Johnny Svensson

    发明人： Stellan Lindberg ,  Johnny Svensson

    IPC分类号： G01N31/00

    CPC分类号： G01N21/03 ,  A61B5/150022 ,  A61B5/15003 ,  A61B5/150099 ,  A61B5/150229 ,  A61B5/150343 ,  A61B5/150755 ,  A61B5/157 ,  G01N15/1475 ,  G01N15/1484 ,  G01N21/11 ,  G01N2015/1486 ,  G01N2021/0321 ,  G01N2021/0325 ,  G01N2021/0346 ,  Y10T436/101666 ,  Y10T436/107497 ,  Y10T436/13

    摘要： A sample acquiring device for volumetric enumeration of white blood cells in a blood sample that includes a measurement cavity for receiving a blood sample. The measurement cavity has a predetermined fixed thickness. The sample acquiring device also has a reagent, which is arranged in a dried form on a surface defining the measurement cavity. The reagent has a hemolysing agent for lysing red blood cells in the sample and a staining agent for selectively staining white blood cells in the sample. Also, a system with the sample acquiring device and a measurement apparatus. The measurement apparatus has a sample acquiring device holder, a light source, and an imaging system for acquiring a digital image of a magnification of the sample The measurement apparatus also has an image analyzer arranged to analyze the acquired digital image for determining the number of white blood cells in the blood sample.

    摘要翻译： 一种用于在血液样本中体积计数白细胞的样本获取装置，其包括用于接收血液样本的测量腔。 测量空腔具有预定的固定厚度。 样品获取装置还具有在限定测量空腔的表面上以干燥形式布置的试剂。 该试剂具有用于裂解样品中红细胞的溶血剂和用于选择性染色样品中白细胞的染色剂。 而且，具有采样装置和测量装置的系统。 测量装置具有取样装置保持器，光源以及用于获取样本的倍数的数字图像的摄像系统。测量装置还具有图像分析装置，被配置为分析所获取的数字图像以确定白色的数量 血液样本中的血细胞。

    Method, device and system for volumetric enumeration of white blood cells
    8.
    发明授权
    Method, device and system for volumetric enumeration of white blood cells 有权
    白细胞体积计数的方法，装置和系统

    公开(公告)号：US08092758B2

    公开(公告)日：2012-01-10

    申请号：US11885637

    申请日：2006-03-10

    申请人： Stellan Lindberg ,  Johnny Svensson

    发明人： Stellan Lindberg ,  Johnny Svensson

    IPC分类号： G01N33/52 ,  G01N33/00

    CPC分类号： G01N21/03 ,  A61B5/150022 ,  A61B5/15003 ,  A61B5/150099 ,  A61B5/150229 ,  A61B5/150343 ,  A61B5/150755 ,  A61B5/157 ,  G01N15/1475 ,  G01N15/1484 ,  G01N21/11 ,  G01N2015/1486 ,  G01N2021/0321 ,  G01N2021/0325 ,  G01N2021/0346 ,  Y10T436/101666 ,  Y10T436/107497 ,  Y10T436/13

    摘要： A sample acquiring device for volumetric enumeration of white blood cells in a blood sample comprises a measurement cavity for receiving a blood sample. The measurement cavity has a predetermined fixed thickness. The sample acquiring device further comprises a reagent, which is arranged in a dried form on a surface defining the measurement cavity. The reagent comprises a hemolysing agent for lysing red blood cells in the blood sample, and a staining agent for selectively staining white blood cells in the blood sample. A system comprises the sample acquiring device and a measurement apparatus. The measurement apparatus comprises a sample acquiring device holder, a light source, and an imaging system for acquiring a digital image of a magnification of the sample. The measurement apparatus further comprises an image analyser arranged to analyse the acquired digital image for determining the number of white blood cells in the blood sample.

    摘要翻译： 用于在血液样本中体积计数白细胞的样本获取装置包括用于接收血液样本的测量腔。 测量空腔具有预定的固定厚度。 样品获取装置还包括在限定测量空腔的表面上以干燥形式布置的试剂。 该试剂包含用于裂解血液样品中的红细胞的溶血剂，以及用于选择性地染色血液样品中的白细胞的染色剂。 系统包括样本获取装置和测量装置。 测量装置包括样本获取装置保持器，光源和用于获取样本的放大倍数的数字图像的成像系统。 测量装置还包括一个图像分析器，被配置为分析所获取的数字图像以确定血液样本中的白细胞数。

    Apparatus and method for analysis of particles in a liquid sample
    9.
    发明申请
    Apparatus and method for analysis of particles in a liquid sample 审中-公开
    用于分析液体样品中颗粒的装置和方法

    公开(公告)号：US20090185734A1

    公开(公告)日：2009-07-23

    申请号：US12314838

    申请日：2008-12-17

    申请人： Stellan Lindberg ,  Tom Olesen ,  Martin Valvik

    发明人： Stellan Lindberg ,  Tom Olesen ,  Martin Valvik

    IPC分类号： G06K9/00 ,  G01N33/48

    CPC分类号： G06K9/00134

    摘要： The invention relates to a measurement apparatus, and method, for analysis of particles in a liquid sample, the apparatus comprising: an image acquiring device, an image analyser, a holder arranged to hold a sample retaining device, and a light refractor positioned between said image acquiring device and said holder; whereby at least one of the image acquiring device, the light refractor and the holder is movable by means of a piezoelectric motor, thereby moving a focus plane within the sample retaining device when it is held by the holder whereby the image acquiring device is adapted to acquire a plurality of images of said sample at different focus planes within the sample retaining device; wherein the image analyser is arranged to analyse at least one acquired image for identifying which of the particles are imaged in focus, and analysing those particles which have been identified as being imaged in focus.

    摘要翻译： 本发明涉及一种用于分析液体样品中的颗粒的测量装置和方法，该装置包括：图像获取装置，图像分析器，设置成保持样品保持装置的保持器和位于所述 图像获取装置和所述保持器; 由此图像获取装置，光折射器和保持器中的至少一个可以通过压电电动机移动，从而当由保持器保持时移动样品保持装置内的聚焦平面，由此图像获取装置适于 在样品保持装置内的不同聚焦平面处获取所述样品的多个图像; 其中所述图像分析器被布置成分析至少一个获取的图像，用于识别聚焦中的哪个颗粒成像，并且分析已经被识别为焦点成像的那些颗粒。