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公开(公告)号：US08686031B2
公开(公告)日：2014-04-01
申请号：US13329601
申请日：2011-12-19
IPC分类号： A61K31/343 , C07D307/80
CPC分类号： C07D307/83
摘要： The present invention provides novel flavonoids extracted from an alcohol extract of dehulled adlay seeds. The present invention also provides a process for the preparation of the flavonoid and a method for treating inflammation in a subject, which method comprises administering to said subject an effective amount of the flavonoid and a pharmaceutically acceptable carrier or excipient.
摘要翻译： 本发明提供从脱壳的楝树种子的醇提取物中提取的新的黄酮类化合物。 本发明还提供了一种制备类黄酮的方法和一种用于治疗受试者的炎症的方法，该方法包括向所述受试者施用有效量的类黄酮和药学上可接受的载体或赋形剂。
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公开(公告)号：US08986754B1
公开(公告)日：2015-03-24
申请号：US14539501
申请日：2014-11-12
发明人： Huang-Chung Tseng , Giao-Zhi Huang , Tung-An Chia
IPC分类号： A01N65/00 , A61K36/8994
CPC分类号： A61K36/8994
摘要： The present invention provides a composition comprising extract of adlay bran, wherein the adlay bran extract comprises C1 to C7 alcohol extract of adlay bran (A) and carbon dioxide supercritical fluid extract of adlay bran (B). Preferably, the extract of adlay bran has effects in treating a skin and/or subcutaneous tissue disease and in lowering interleukin (IL)-1α, interleukin-1β, interleukin-6, tumor necrosis factor (TNF)-α, interleukin-8, prostaglandin-2 (PGE2) and/or C-Reactive Protein (CRP).
摘要翻译： 本发明提供一种包含麸皮提取物的组合物，其中所述麸皮提取物包含麸皮（A）的C1-C7醇提取物和麸皮（B）的二氧化碳超临界流体提取物。 优选地，麸皮提取物具有治疗皮肤和/或皮下组织疾病和降低白细胞介素（IL）-1α，白细胞介素-1bb，白细胞介素-6，肿瘤坏死因子（TNF）-α，白细胞介素-8 ，前列腺素-2（PGE2）和/或C-反应蛋白（CRP）。
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公开(公告)号：US08911800B2
公开(公告)日：2014-12-16
申请号：US13839538
申请日：2013-03-15
发明人： Huang-Chung Tseng , Giao-Zhi Huang , Tung-An Chia
IPC分类号： A01N65/00 , A61K36/8994
CPC分类号： A61K36/8994
摘要： The present invention provides a composition comprising extract of adlay bran, wherein the adlay bran extract comprises C1 to C7 alcohol extract of adlay bran (A) and carbon dioxide supercritical fluid extract of adlay bran (B). Preferably, the extract of adlay bran has effects in treating a skin and/or subcutaneous tissue disease and in lowering interleukin (IL)-1α, interleukin-1β, interleukin-6, tumor necrosis factor (TNF)-α, interleukin-8, prostaglandin-2 (PGE2) and/or C-Reactive Protein (CRP).
摘要翻译： 本发明提供一种包含麸皮提取物的组合物，其中所述麸皮提取物包含麸皮（A）的C1〜C7醇提取物和麸皮（B）的二氧化碳超临界流体提取物。 优选地，麸皮提取物具有治疗皮肤和/或皮下组织疾病和降低白细胞介素（IL）-1α，白细胞介素-1bb，白细胞介素-6，肿瘤坏死因子（TNF）-α，白细胞介素-8 ，前列腺素-2（PGE2）和/或C-反应蛋白（CRP）。
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公开(公告)号：US20140093597A1
公开(公告)日：2014-04-03
申请号：US13845614
申请日：2013-03-18
IPC分类号： A61K36/77
CPC分类号： A61K36/77 , A61K2236/00
摘要： The present invention provides use of alcohol extract of longan seeds for manufacturing a drug for treating kidney tissue dysfunction. Preferably, an ethyl acetate sub-fraction of the alcohol extract of longan seeds has a better effect in treating kidney tissue dysfunction.
摘要翻译： 本发明提供龙眼种子的醇提取物的制造用于治疗肾组织功能障碍的药物的用途。 优选地，龙眼种子的醇提取物的乙酸乙酯亚组分在治疗肾组织功能障碍方面具有更好的效果。
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公开(公告)号：US08633238B2
公开(公告)日：2014-01-21
申请号：US13364098
申请日：2012-02-01
IPC分类号： A61K31/407 , C07D491/107
CPC分类号： C07D491/107
摘要： The present invention provides novel lactams extracted from an alcohol extract of dehulled adlay seeds. The present invention also provides a process for the preparation of the lactams and a method for treating breast cancer in a subject, which method comprises administering to said subject an effective amount of the lactam and a pharmaceutically acceptable carrier or excipient.
摘要翻译： 本发明提供从脱壳的阿德莱种子的醇提取物提取的新型内酰胺。 本发明还提供了制备内酰胺的方法和用于治疗受试者的乳腺癌的方法，该方法包括向所述受试者施用有效量的内酰胺和药学上可接受的载体或赋形剂。
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公开(公告)号：US09999645B2
公开(公告)日：2018-06-19
申请号：US14327393
申请日：2014-07-09
发明人： Huang-Chung Tseng , Chien-Wei Hou
CPC分类号： A61K36/77 , Y02A50/473
摘要： A method of making longan seed extract is provided with choosing an extraction solvent; heating the extraction solvent to a first predetermined temperature; adding pulverized longan seed to the extraction solvent to prepare a solution; maintaining the solution at a second temperature for a predetermined period of time to obtain an extracted substance; filtering the extracted substance; and drying and cooling the filtered extracted substance to produce an extract.
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公开(公告)号：US09744205B2
公开(公告)日：2017-08-29
申请号：US13364055
申请日：2012-02-01
IPC分类号： A61K36/8994 , A23L7/10 , A23L33/105
CPC分类号： A61K36/8994 , A23L7/115 , A23L33/105
摘要： The present invention provides a method for treating breast cancer in a subject, which comprises administering to said subject an effective amount of an alcohol extract of dehulled adlay seeds. Preferably, an ethyl acetate sub-fraction of the alcohol extract of dehulled adlay seeds has a better effect in treating breast cancer.
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公开(公告)号：US09259451B2
公开(公告)日：2016-02-16
申请号：US13845614
申请日：2013-03-18
IPC分类号： A61K36/77 , A61K36/185
CPC分类号： A61K36/77 , A61K2236/00
摘要： The present invention provides use of alcohol extract of longan seeds for manufacturing a drug for treating kidney tissue dysfunction. Preferably, an ethyl acetate sub-fraction of the alcohol extract of longan seeds has a better effect in treating kidney tissue dysfunction.
摘要翻译： 本发明提供龙眼种子的醇提取物的制造用于治疗肾组织功能障碍的药物的用途。 优选地，龙眼种子的醇提取物的乙酸乙酯亚组分在治疗肾组织功能障碍方面具有更好的效果。
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公开(公告)号：US09308233B2
公开(公告)日：2016-04-12
申请号：US14613094
申请日：2015-02-03
发明人： Huang-Chung Tseng , Giao-Zhi Huang , Tung-An Chia
IPC分类号： A01N65/00 , A61K36/8994
CPC分类号： A61K36/8994
摘要： The present invention provides a composition comprising extract of adlay bran, wherein the adlay bran extract comprises C1 to C7 alcohol extract of adlay bran (A) and carbon dioxide supercritical fluid extract of adlay bran (B). Preferably, the extract of adlay bran has effects in treating a skin and/or subcutaneous tissue disease and in lowering interleukin (IL)-1α, interleukin-1β, interleukin-6, tumor necrosis factor (TNF)-α, interleukin-8, prostaglandin-2 (PGE2) and/or C-Reactive Protein (CRP).
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10.发明授权Alcohol extract of dehulled adlay seeds for treating gastric ulcer and/or stomach cancer 有权用于治疗胃溃疡和/或胃癌的脱皮adlay种子的酒精提取物公开(公告)号：US08945638B2
公开(公告)日：2015-02-03
申请号：US13304566
申请日：2011-11-25
IPC分类号： A61K36/8994
CPC分类号： A61K36/8994
摘要： The present invention provides a method for treating gastric ulcer and/or stomach cancer in a subject, which comprises administering to said subject an effective amount of an alcohol extract of dehulled adlay seeds. Preferably, an ethyl acetate sub-fraction of the alcohol extract of dehulled adlay seeds has a better effect in treating gastric ulcer and/or stomach cancer.
摘要翻译： 本发明提供了一种用于治疗受试者的胃溃疡和/或胃癌的方法，其包括向所述受试者施用有效量的脱皮的lay粒种子的醇提取物。 优选地，脱皮的adlay种子的醇提取物的乙酸乙酯亚组分在治疗胃溃疡和/或胃癌方面具有更好的效果。
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