公开(公告)号：US08686031B2

公开(公告)日：2014-04-01

申请号：US13329601

申请日：2011-12-19

申请人： Wenchang Chiang ,  Yun-Lian Lin ,  Cheng-Pei Chung ,  Hong-Jhang Chen

发明人： Wenchang Chiang ,  Yun-Lian Lin ,  Cheng-Pei Chung ,  Hong-Jhang Chen

IPC分类号： A61K31/343 ,  C07D307/80

CPC分类号： C07D307/83

摘要： The present invention provides novel flavonoids extracted from an alcohol extract of dehulled adlay seeds. The present invention also provides a process for the preparation of the flavonoid and a method for treating inflammation in a subject, which method comprises administering to said subject an effective amount of the flavonoid and a pharmaceutically acceptable carrier or excipient.

摘要翻译： 本发明提供从脱壳的楝树种子的醇提取物中提取的新的黄酮类化合物。 本发明还提供了一种制备类黄酮的方法和一种用于治疗受试者的炎症的方法，该方法包括向所述受试者施用有效量的类黄酮和药学上可接受的载体或赋形剂。

公开(公告)号：US09744205B2

公开(公告)日：2017-08-29

申请号：US13364055

申请日：2012-02-01

申请人： Wenchang Chiang ,  Yueh-Hsiung Kuo ,  Yun-Lian Lin ,  Cheng-Pei Chung

发明人： Wenchang Chiang ,  Yueh-Hsiung Kuo ,  Yun-Lian Lin ,  Cheng-Pei Chung

IPC分类号： A61K36/8994 ,  A23L7/10 ,  A23L33/105

CPC分类号： A61K36/8994 ,  A23L7/115 ,  A23L33/105

摘要： The present invention provides a method for treating breast cancer in a subject, which comprises administering to said subject an effective amount of an alcohol extract of dehulled adlay seeds. Preferably, an ethyl acetate sub-fraction of the alcohol extract of dehulled adlay seeds has a better effect in treating breast cancer.

公开(公告)号：US08633238B2

公开(公告)日：2014-01-21

申请号：US13364098

申请日：2012-02-01

申请人： Wenchang Chiang ,  Yueh-Hsiung Kuo ,  Yun-Lian Lin ,  Cheng-Pei Chung

发明人： Wenchang Chiang ,  Yueh-Hsiung Kuo ,  Yun-Lian Lin ,  Cheng-Pei Chung

IPC分类号： A61K31/407 ,  C07D491/107

CPC分类号： C07D491/107

摘要： The present invention provides novel lactams extracted from an alcohol extract of dehulled adlay seeds. The present invention also provides a process for the preparation of the lactams and a method for treating breast cancer in a subject, which method comprises administering to said subject an effective amount of the lactam and a pharmaceutically acceptable carrier or excipient.

摘要翻译： 本发明提供从脱壳的阿德莱种子的醇提取物提取的新型内酰胺。 本发明还提供了制备内酰胺的方法和用于治疗受试者的乳腺癌的方法，该方法包括向所述受试者施用有效量的内酰胺和药学上可接受的载体或赋形剂。

公开(公告)号：US08945638B2

公开(公告)日：2015-02-03

申请号：US13304566

申请日：2011-11-25

申请人： Wenchang Chiang ,  Yueh-Hsiung Kuo ,  Yun-Lian Lin ,  Cheng-Pei Chung

发明人： Wenchang Chiang ,  Yueh-Hsiung Kuo ,  Yun-Lian Lin ,  Cheng-Pei Chung

IPC分类号： A61K36/8994

CPC分类号： A61K36/8994

摘要： The present invention provides a method for treating gastric ulcer and/or stomach cancer in a subject, which comprises administering to said subject an effective amount of an alcohol extract of dehulled adlay seeds. Preferably, an ethyl acetate sub-fraction of the alcohol extract of dehulled adlay seeds has a better effect in treating gastric ulcer and/or stomach cancer.

摘要翻译： 本发明提供了一种用于治疗受试者的胃溃疡和/或胃癌的方法，其包括向所述受试者施用有效量的脱皮的lay粒种子的醇提取物。 优选地，脱皮的adlay种子的醇提取物的乙酸乙酯亚组分在治疗胃溃疡和/或胃癌方面具有更好的效果。

公开(公告)号：US08648215B2

公开(公告)日：2014-02-11

申请号：US13364127

申请日：2012-02-01

申请人： Wenchang Chiang ,  Yueh-Hsiung Kuo ,  Yun-Lian Lin ,  Cheng-Pei Chung

发明人： Wenchang Chiang ,  Yueh-Hsiung Kuo ,  Yun-Lian Lin ,  Cheng-Pei Chung

IPC分类号： C07C45/79 ,  C07C49/753 ,  A61K31/122

CPC分类号： A61K36/8994 ,  A61K2236/00 ,  C07C45/79 ,  C07C45/80 ,  C07C49/753

摘要： The present invention provides novel spiroenones extracted from an alcohol extract of dehulled adlay seeds. The present invention also provides a process for the preparation of the spiroenones and a method for treating breast cancer in a subject, which method comprises administering to said subject an effective amount of the spiroenone and a pharmaceutically acceptable carrier or excipient.

摘要翻译： 本发明提供从脱壳的楝树种子的醇提取物中提取的新型螺旋酮。 本发明还提供了制备螺旋酮的方法和用于治疗受试者的乳腺癌的方法，该方法包括向所述受试者施用有效量的螺螺酮和药学上可接受的载体或赋形剂。