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公开(公告)号：US20040210201A1
公开(公告)日：2004-10-21
申请号：US10748395
申请日：2003-12-30
申请人： Novoste Corporation
发明人： Robert C. Farnan
IPC分类号： A61M005/00
CPC分类号： A61M39/04 , A61M5/14 , A61M5/16804 , A61M39/20 , A61M2005/1404
摘要： The present invention is directed to a method and apparatus for maintaining the patency of vascular catheter lumens so as to keep such lumens open and unobstructed when an indwelling catheter is not being used to administer treatment.
摘要翻译： 本发明涉及一种用于维持血管导管腔的通畅性的方法和装置，以便当不使用留置导管进行治疗时，保持这样的内腔开放和畅通无阻。
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2.发明申请公开(公告)号：US20040044305A1
公开(公告)日：2004-03-04
申请号：US10385107
申请日：2003-03-10
申请人： Novoste Corporation
IPC分类号： A61M031/00
CPC分类号： A61N5/1007 , A61N5/1002 , A61N2005/1008
摘要： A system comprising a microprocessor-controlled transfer device and a separate catheter for intraluminal treatment of a selected site in a body of a patient by at least one treating element advanced from a removable treating element cartridge received in the transfer device into a lumen of the separate catheter by means of pressurized fluid controlled by a fluid control switch moveable between send and return positions. A safety interlock is provided for preventing both (1) the disassembly of the system unless the treating element resides in the treating element cartridge and (2) the actuation of the fluid control switch unless the system is assembled. The safety interlock comprises a first lock moveable from a first position to a second position only if both the catheter and the treating element cartridge are secured to the transfer device. The first lock blocks the movement of the fluid control switch to the send position when in its first position and prevents disassembly of either the catheter or the treating element cartridge from the transfer device when in its second position. The fluid control switch further locks the first lock into its second position when the fluid control switch is in the send position. A system is also provided for detecting whether the treating element resides at a targeted location along the lumen of the transfer device. The detection system comprises a pressure transducer that is in fluid communication with the lumen of the transfer device so as to be capable of measuring the fluid pressure at the targeted location of the lumen. Circuitry is provided for comparing the measured pressure to a reference pressure corresponding to the pressure at the targeted location when the treating elements are stored at the targeted location under fluid pressure. A signal generator provides a signal when the measured pressure differs from the reference pressure by more than a predetermined amount. The signal may activate an optical signal and/or a mechanical interlock, the latter preventing separation of the catheter from the transfer device and preventing closure of the gate when activated by a signal from the signal generator corresponding to the pressure encountered when the treating element does not reside at the targeted location.
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公开(公告)号：US20030229259A1
公开(公告)日：2003-12-11
申请号：US10411749
申请日：2003-04-11
申请人： Novoste Corporation
发明人： Ron Waksman , Thomas D. Weldon , Richard A. Hillstead , Jonathan J. Rosen , Charles E. Larsen , Ian R. Crocker , Raphael F. Meloul
IPC分类号： A61N005/00
CPC分类号： A61M25/1002 , A61M25/0028 , A61M25/003 , A61M25/0032 , A61M25/1006 , A61M2025/0034 , A61N5/1002 , A61N5/1007
摘要： Apparatus and method are described for delivery of a treating element, such as a radiation source, through a catheter to a desired site in the vascular system of a patient, such as a coronary artery, for inhibiting the formation of scar tissue such as may occur in restenosis following balloon angioplasty. The apparatus includes an elongated flexible catheter tube having proximal and distal end portions, with a lumen extending therebetween, and a diameter sufficiently small for insertion in to a patient's vascular system. One or more treating elements, such as a capsule or pellet containing radioactive material, is positionable within the lumen and movable between the proximal and distal end portions under the force of liquid flowing through the lumen. A method for using such apparatus, including a method for using such apparatus simultaneously with a balloon angioplasty procedure, is disclosed.
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公开(公告)号：USD374076S
公开(公告)日：1996-09-24
申请号：US24444
申请日：1994-06-14
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公开(公告)号：US5195990A
公开(公告)日：1993-03-23
申请号：US757684
申请日：1991-09-11
申请人： Thomas D. Weldon
发明人： Thomas D. Weldon
IPC分类号： A61M25/00
CPC分类号： A61M25/0041
摘要： The coronary catheter of the present invention has an elongated tubular member or shaft, with a proximal end portion and the distal end portion. The distal end portion terminates in a tip end portion. In accordance with the present invention, the distal end portion of the catheter is curved in three dimensions and cooperative with the shape of the human aortic arch so as to automatically place the tip end of the catheter into proximity with the right coronary ostium as the distal end portion passes over the aortic arch and into the ascending aorta.
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6.发明申请Catheter for treatment of total occlusions and methods for manufacture and use of the catheter 有权用于治疗全部闭塞的导管以及制造和使用导管的方法公开(公告)号：US20060264821A1
公开(公告)日：2006-11-23
申请号：US11291758
申请日：2005-12-01
申请人： Minh Vo , Cory Anderson
发明人： Minh Vo , Cory Anderson
IPC分类号： A61M31/00
CPC分类号： A61M25/0015 , A61M25/0009 , A61M25/0043 , A61M2025/1052
摘要： A catheter for treatment of chronic total occlusions includes an occlusion breach device, a catheter body made of a temperature-dependent softening, shape-memory, thermoplastic polymer having a first flexible state and a second stiff state. The catheter body has a heat transfer conduit and a conduit for slidably receiving the breach device. A heat-transferring device selectively changes a temperature of the heat transfer conduit to, thereby, change stiffness of the catheter body between the two states. To treat a CTO with the catheter, it is warmed above the glass-transition temperature and below the melting-temperature to make the catheter flexible. The catheter has a shape when inserted at the occlusion site and is cooled to, thereby, stiffen. Breaching of the occlusion is assisted with the stiff catheter. The catheter is removed by warming the polymer. Also provided is a method for manufacturing such a selectively stiffening catheter.
摘要翻译： 用于治疗慢性完全闭塞的导管包括闭塞突破装置，由温度依赖性软化形状记忆体形成的导管体，具有第一柔性状态和第二僵硬状态的热塑性聚合物。 导管主体具有传热导管和用于可滑动地接收突破装置的导管。 传热装置选择性地改变传热管道的温度，从而改变导管体在两种状态之间的刚度。 为了用导管治疗CTO，将其温度高于玻璃化转变温度并低于熔融温度，以使导管变得柔软。 导管在插入位置时具有形状并被冷却，从而变硬。 使用刚性导管辅助阻塞闭塞。 通过加热聚合物去除导管。 还提供了制造这种选择性加强导管的方法。
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7.发明授权Automated system for the radiation treatment of a desired area within the body of a patient 有权用于辐射治疗患者体内所需区域的自动化系统公开(公告)号：US06863658B2
公开(公告)日：2005-03-08
申请号：US10385107
申请日：2003-03-10
CPC分类号： A61N5/1007 , A61N5/1002 , A61N2005/1008
摘要： A system comprising a microprocessor-controlled transfer device and a separate catheter for intraluminal treatment of a selected site in a body of a patient by at least one treating element advanced from a removable treating element cartridge received in the transfer device into a lumen of the separate catheter by means of pressurized fluid controlled by a fluid control switch moveable between send and return positions, and a safety interlock for use with the system.
摘要翻译： 一种系统，包括微处理器控制的转移装置和单独的导管，用于通过至少一个处理元件进行管腔内处理患者体内的选定部位，所述至少一个处理元件从容纳在所述转移装置中的可移除处理元件筒进入到分离的内腔中 通过由可在发送和返回位置之间移动的流体控制开关控制的加压流体以及用于该系统的安全联锁来进行导管。
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公开(公告)号：US5806551A
公开(公告)日：1998-09-15
申请号：US409756
申请日：1995-03-24
CPC分类号： A61M5/16877 , A61M39/26 , F16K7/02 , A61M2039/267 , Y10S604/905 , Y10T137/0318
摘要： An automatic fluid control having a first and second tube members and a slidable valve element capable of moving from a sealed closed position to an open position permitting fluid passage therethrough. In a preferred first embodiment, the elastomeric valve element is slidingly received with a passageway in the first tube. The valve element has a flange portion containing a plurality of slits that, when inverted and stretched, permit fluid to pass therethrough, but when closed, are in contact with the inner wall of the first tube and prevents fluid from passing therethrough. The valve element also can have a rigid plug attached within an opening in the top surface to present a preferably non-deformable contact point for a male luer tip, which, when pressed downward on the valve element, breaks a seal between the valve element and the first tube inner wall. In a second embodiment a toroidal shaped valve portion selectively forms a seal over a pin extending axially from the second tube member, the pin having a plurality of grooves in its surface to permit passage of fluid when the seal created by the valve element is broken. In a third embodiment, a valve element maintains a seal against a pin extending from the base of the second tube member and having a plurality of grooves. When the valve element is urged downward against the upward force of a spring, the pin grooves permit fluid flow through the second tube member.
摘要翻译： 具有第一和第二管构件的自动流体控制和能够从密封的关闭位置移动到允许流体通过其中的打开位置的可滑动阀元件。 在优选的第一实施例中，弹性阀元件以第一管中的通道滑动地容纳。 阀元件具有凸缘部分，该凸缘部分包含多个狭缝，当反向和拉伸时，允许流体通过，但是当关闭时，它们与第一管的内壁接触并防止流体通过。 阀元件还可以具有附接在顶表面中的开口内的刚性插塞，以呈现用于阳性鲁尔末端的优选不可变形的接触点，当阳性鲁尔末端向下压在阀元件上时，其破坏阀元件和 第一管内壁。 在第二实施例中，环形阀部分选择性地在从第二管构件轴向延伸的销上形成密封，该销在其表面上具有多个槽，以在由阀元件产生的密封件断裂时允许流体通过。 在第三实施例中，阀元件保持密封抵靠从第二管构件的基部延伸并具有多个槽的销。 当阀元件抵抗弹簧向上的力被向下推动时，销槽允许流体流过第二管件。
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公开(公告)号：US5755702A
公开(公告)日：1998-05-26
申请号：US635496
申请日：1996-04-22
CPC分类号： A61M25/0662 , A61M25/0097
摘要： A sheath introducer for a catheterization or similar procedure comprises a main body having an exterior tapered sidewall, an interior lumen, a beveled top surface and an annular boss extending from the top surface; a rotating section having an exterior sidewall, an interior lumen, a beveled bottom surface having a recessed portion dimensioned so as to be received within the main body annular boss, and a top surface having an annular shoulder extending therefrom creating a recess; a cannula extending from the bottom end of the main body; and, a hemostatic valve having an access port and a fluid tight slit opening and seated within the upper portion and maintained by a cap, the valve being maintained within the rotating section recess and preferably slightly compressed when the rotating section and main body are assembled. When assembled, the rotating section can rotate up to approximately 180.degree., affording approximately a 45.degree. angle between the main body lumen and the rotating section lumen while maintaining an open passageway for insertion of catheters or other objects. Optionally, an angled sideport in fluid communication with the main body lumen extends from the main body.
摘要翻译： 用于导管插入或相似程序的护套引导器包括具有外锥形侧壁，内腔，斜面顶表面和从顶表面延伸的环形凸起的主体; 具有外侧壁的旋转部分，内腔，具有凹部的斜面底面，其尺寸设计成容纳在主体环形凸台内，以及顶表面，其具有从其延伸的环形肩部，形成凹部; 从主体的底端延伸的套管; 以及具有进入口和流体密封狭缝开口并位于上部并由盖保持的止血阀，所述阀保持在旋转部分凹部内，并且优选地在旋转部分和主体组装时略微压缩。 当组装时，旋转部分可以旋转大约180度，在主体腔和旋转部分腔体之间提供大致45度的角度，同时保持用于插入导管或其它物体的开放通道。 可选地，与主体内腔流体连通的倾斜侧面从主体延伸。
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公开(公告)号：US5509908A
公开(公告)日：1996-04-23
申请号：US230614
申请日：1994-04-21
CPC分类号： A61M25/0662 , A61M25/0097
摘要： A sheath introducer for a catheterization or similar procedure comprises a body having a upper portion and a lower portion, the lower portion being angled with respect to the upper portion; a curved tapering channel extending through the upper and lower portions; a cannula with a tapered distal end extending at an angle with respect to the upper portion a hemostatic valve having an access port and a fluid tight slit opening and seated within the upper portion and maintained by a cap; and an angled sideport in fluid communication with the channel. Optionally, a wiper flange extends inward within the valve access port which provide an additional fluid tight seal when a catheter is slidingly inserted, removed or maintained within the valve. A dilator can be adapted for use with the introducer by having a bend in the tube portion of the dilator.
摘要翻译： 用于导管插入或类似程序的护套引导器包括具有上部和下部的主体，下部相对于上部成一定角度; 延伸穿过上部和下部的弯曲的锥形通道; 具有锥形远端的套管，所述套管具有相对于所述上部一定角度延伸的止血阀，所述止血阀具有进入口和流体密封狭缝开口，并位于所述上部内并由盖保持; 以及与通道流体连通的倾斜侧台。 可选地，擦拭器凸缘在阀进入端口内向内延伸，当导管滑动地插入，移除或保持在阀内时，提供另外的流体密封。 扩张器可以通过在扩张器的管部分中具有弯曲而适于与导引器一起使用。
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