公开(公告)号：US20110082493A1

公开(公告)日：2011-04-07

申请号：US12966311

申请日：2010-12-13

申请人： Gene Samson ,  Harold F. Carrison

发明人： Gene Samson ,  Harold F. Carrison

IPC分类号： A61F2/01

CPC分类号： A61F2/013 ,  A61B17/221 ,  A61B90/39 ,  A61B2017/22034 ,  A61B2017/22045 ,  A61B2017/22084 ,  A61B2017/2212 ,  A61B2090/376 ,  A61F2/01 ,  A61F2002/011 ,  A61F2002/016 ,  A61F2230/0006 ,  A61F2230/005 ,  A61F2230/0067 ,  A61F2230/0071

摘要： This is a surgical device usually delivered through an intravascular catheter. It may be used in several ways. It may, for instance, be used to open a clear passageway adjacent thrombus to allow both blood and medication to bypass the clot. It may be used to pierce and to remove thrombus. These thrombus are often found in tortuous vasculature. The device includes several sections. The device has a core element, typically a core wire. Placed around the distal end of the core element is a collapsible but preferably self expanding proximal cage assembly and a distal filter, preferably a self-expanding cage assembly or other filter component. The various portions of those components are preferably radio-opaque. The proximal end of the proximal cage is typically is affixed to an actuator in such a way as to allow expansion of the cage after deployment. The proximal cage assembly may be used for collecting emboli or for displacing them to allow blood flow to resume, either with or without concurrent clot-dissolving drug treatment. The distal sector, whether a self-expanding cage or fan, is placed distally of the thrombus to collect portions of the thrombus which may loosen during the treatment or removal procedure.

摘要翻译： 这是通常通过血管内导管递送的手术装置。 它可以以几种方式使用。 例如，它可以用于打开邻近血栓的清晰通道，以允许血液和药物绕过凝块。 它可以用于刺穿和去除血栓。 这些血栓通常在曲折的脉管系统中发现。 该设备包括几个部分。 该装置具有核心元件，通常为芯线。 围绕芯元件的远端放置的是可折叠但优选自扩张的近端保持器组件和远端过滤器，优选自膨胀笼组件或其它过滤器部件。 这些部件的各个部分优选地是不透射线的。 近端保持架的近端通常被固定到致动器上，以允许在展开之后使笼膨胀。 近端笼组件可用于收集栓塞或用于置换它们以允许血流恢复，无论是否伴有凝血溶解药物治疗。 远端部分，无论是自膨胀笼或风扇，是否位于血栓的远端，以收集在治疗或移除手术过程中可能松动的部分血栓。

公开(公告)号：US20110024025A1

公开(公告)日：2011-02-03

申请号：US12906872

申请日：2010-10-18

申请人： Jill M. McFadden ,  Earl Bardsley ,  Robert Garabedian

发明人： Jill M. McFadden ,  Earl Bardsley ,  Robert Garabedian

IPC分类号： B29C70/10

CPC分类号： A61M25/0045 ,  A61B5/6852 ,  A61M25/0053 ,  A61M25/0054 ,  Y10T29/49801

摘要： A catheter section comprising an elongate tubular member having a proximal end, a distal end, and a passageway defining a lumen extending between the proximal and distal ends. The elongate tubular member includes a knit tubular member and an inner tubular liner in coaxial relationship with the knit tubular member. The catheter section is for use as a distal section in a catheter having a relatively stiff proximal section.

摘要翻译： 一种导管部分，包括细长的管状部件，其具有近端，远端以及限定在近端和远端之间延伸的内腔的通道。 细长管状构件包括编织管状构件和与针织管状构件同轴关系的内部管状衬垫。 导管部分用作具有相对刚性近端部分的导管中的远侧部分。

公开(公告)号：US07875050B2

公开(公告)日：2011-01-25

申请号：US10082492

申请日：2002-02-22

申请人： Gene Samson ,  Harold F Carrison

发明人： Gene Samson ,  Harold F Carrison

IPC分类号： A61M29/00

CPC分类号： A61F2/013 ,  A61B17/221 ,  A61B90/39 ,  A61B2017/22034 ,  A61B2017/22045 ,  A61B2017/22084 ,  A61B2017/2212 ,  A61B2090/376 ,  A61F2/01 ,  A61F2002/011 ,  A61F2002/016 ,  A61F2230/0006 ,  A61F2230/005 ,  A61F2230/0067 ,  A61F2230/0071

摘要： An embolism treatment device includes an elongated core wire having a coil tip coupled to the distal end of the core wire and a cage assembly substantially coaxial to the core wire, having a first deployment shape and a second expanded shape. The core wire is freely moveable axially through the cage assembly. The device additionally includes an inner coil surrounding the core wire within the cage assembly and an actuator element, having a first position and a second position, located proximally to the cage assembly, wherein when the actuator element is in the first position, the cage assembly is in the first deployment shape and when the actuator element is in the second position, the cage assembly is in the second expanded shape.

摘要翻译： 栓塞治疗装置包括细长的芯线，其具有联接到芯线的远端的线圈末端和与芯线基本同轴的保持架组件，具有第一展开形状和第二扩张形状。 芯线可以轴向自由移动通过保持架组件。 该装置还包括围绕保持架组件内的芯线的内部线圈和具有位于保持架组件的近侧的第一位置和第二位置的致动器元件，其中当致动器元件处于第一位置时，保持架组件 处于第一展开形状，并且当致动器元件处于第二位置时，保持架组件处于第二展开形状。

公开(公告)号：US20070049903A1

公开(公告)日：2007-03-01

申请号：US11516061

申请日：2006-09-06

申请人： Lex Jansen ,  Thomas Chien ,  Perry Fukui ,  Jeffrey Sarge ,  Lawrence Alpert

发明人： Lex Jansen ,  Thomas Chien ,  Perry Fukui ,  Jeffrey Sarge ,  Lawrence Alpert

IPC分类号： A61M25/00

CPC分类号： A61M25/0053 ,  A61M25/005 ,  A61M25/0054

摘要： A catheter comprising an elongate tubular member having a proximal end, a distal end, and a passageway defining a lumen extending between the proximal and distal ends. The elongate tubular member comprises a relatively stiff proximal section and a relatively flexible distal section. The proximal section includes an inner tubular liner, a first stiffener comprising a metal alloy, and a second stiffener comprising a non-metal alloy. The first and second stiffeners are coaxially wound exterior to the proximal inner liner. The distal section includes a distal inner tubular liner and the second stiffener coaxially wound exterior to the distal inner liner. The first stiffener terminates before reaching the distal section.

摘要翻译： 导管，其包括具有近端，远端和限定在所述近端和远端之间延伸的内腔的通道的细长管状构件。 细长管状构件包括相对刚性的近端部分和相对柔性的远端部分。 近端部分包括内部管状衬垫，包括金属合金的第一加强件和包括非金属合金的第二加强件。 第一和第二加强件同轴地缠绕在近端内衬的外部。 远侧部分包括远侧内部管状衬垫，并且第二加强件同轴地缠绕在远端内衬套的外部。 第一加强件在到达远端部分之前终止。

公开(公告)号：US20030004461A1

公开(公告)日：2003-01-02

申请号：US10211399

申请日：2002-08-02

申请人： Target Therapeutics, Inc.

发明人： David Kupiecki

IPC分类号： A61M029/00

CPC分类号： A61M25/0075 ,  A61B17/12022 ,  A61B17/12109 ,  A61B17/12136 ,  A61B17/12186 ,  A61B2017/1205 ,  A61M25/104 ,  A61M2025/1052 ,  A61M2025/1063

摘要： This is a medical catheter made up of a body having on its distal end portion an expandable balloon and, proximal of the balloon, a delivery lumen ending in a port through which therapeutic or diagnostic agents may be delivered. In one variation, a single inflation/wire lumen extends from the catheter proximal end to the catheter distal end, through which the balloon is inflated with pressurized fluid and through which a guide wire extends. The guide wire may have a valve plug for selectively seating against a valve seat of the catheter distal end to seal the inflation/wire lumen for balloon inflations. In another variation, a vaso-occlusive agent is disposable within a delivery lumen in a catheter coupled with a steerable guidewire. The delivery lumen ends in a delivery port near to and proximal of an expandable balloon located at the catheter's end. A single inflation/wire lumen may also be provided for facilitating both balloon inflation and guide wire tracking.

公开(公告)号：US6066158A

公开(公告)日：2000-05-23

申请号：US686304

申请日：1996-07-25

申请人： Erik T. Engelson ,  Gene Samson

发明人： Erik T. Engelson ,  Gene Samson

IPC分类号： A61B17/22 ,  A61F2/958 ,  A61M29/00 ,  A61M29/02

CPC分类号： A61B17/3207 ,  A61B17/221 ,  A61B17/320725 ,  A61B17/32075 ,  A61B2017/22034 ,  A61B2017/22061 ,  A61B2017/2212 ,  A61M2025/1095 ,  A61M25/10 ,  A61M29/02

摘要： This is a surgical device usually delivered through an intravascular catheter. It is designed to pierce and remove emboli often found in tortuous vasculature. The device includes several sections. The device has a core element. Placed around the distal end of the core wire is a collapsible but self expanding embolism collection assembly. That collector assembly is typically joined to the core wire at its distal end. The collector assembly may have a generally conical distal portion when expanded and may have a proximal section having varied purposes, e.g. for centering the collector assembly in the vascular lumen. The assembly further may have an actuator which permits the collector assembly to expand after deployment.

摘要翻译： 这是通常通过血管内导管递送的手术装置。 它旨在刺穿和去除经常在弯曲脉管系统中发现的栓子。 该设备包括几个部分。 该设备具有核心元件。 放置在芯线远端的是可折叠但自膨胀的栓塞收集组件。 该集电器组件通常在其远端处连接到芯线。 收集器组件可以在膨胀时具有大致锥形的远侧部分，并且可以具有不同目的的近端部分，例如， 用于将收集器组件对准在血管腔中。 组件还可以具有致动器，其允许收集器组件在展开之后膨胀。

公开(公告)号：US6056761A

公开(公告)日：2000-05-02

申请号：US743494

申请日：1996-11-04

申请人： Son Gia ,  Hong Doan ,  Pete Phong Pham ,  Ivan Sepetka ,  U. Hiram Chee ,  Michael Mariant ,  David Kupiecki

发明人： Son Gia ,  Hong Doan ,  Pete Phong Pham ,  Ivan Sepetka ,  U. Hiram Chee ,  Michael Mariant ,  David Kupiecki

IPC分类号： A61F2/82 ,  A61B17/00 ,  A61B17/12 ,  A61F2/06 ,  A61F2/84 ,  A61B17/08

CPC分类号： A61B17/12022 ,  A61B17/12113 ,  A61B17/12145 ,  A61B2017/00017 ,  A61B2017/00292 ,  A61B2017/12063 ,  A61B2018/1495 ,  A61F2/95

摘要： A solderless sacrificial link between a detachable member which is placed at and is intended to remain at a desired site within the mammalian body and the core wire used to introduce the detachable member. The detachable member device may be one used to create emboli in the vascular system or may be of any other type deliverable into the human body and detached into an ionic aqueous environment, either for later removal or permanent placement.

摘要翻译： 放置在哺乳动物体内的期望部位并且旨在保持在哺乳动物体内的期望部位的可拆卸部件与用于引入可拆卸部件的芯线之间的无焊接牺牲连接。 可拆卸构件装置可以是用于在血管系统中产生栓塞的构件装置，或者可以是可输送到人体内并且分离成离子水性环境的任何其它类型的装置，用于随后的移除或永久放置。

公开(公告)号：US6036720A

公开(公告)日：2000-03-14

申请号：US990314

申请日：1997-12-15

申请人： Robert M. Abrams ,  Daniel R. Kurz

发明人： Robert M. Abrams ,  Daniel R. Kurz

IPC分类号： A61B17/12 ,  A61B17/08

CPC分类号： A61B17/12022 ,  A61B17/12113 ,  A61B17/1214 ,  A61B17/12172 ,  A61B2017/12063

摘要： This is a device for bridging the necks of wide-necked or narrow-necked aneurysms in the vasculature. It is a device which may be used by itself to bridge the neck of an aneurysm or used to stabilize the presence of other vaso-occlusive devices such as helically wound coils in that aneurysm. The included vaso-occlusive devices may be delivered to the aneurysm in a variety of different ways, e.g., by a core wire which is linked to the coils by an electrolytically severable or mechanically detachable joint. The vaso-occlusive devices may also be simply pushed into the aneurysm. The aneurysm neck bridge may also be delivered in a variety of ways, but preferably is attached to an electrolytically severable joint for its deployment. The inventive neck bridge may contain one or two sections: a first or inner section to be placed within the aneurysm and an optional second or outer section suitably placed outside the aneurysm. The first section typically has a number of array elements which are intended to be resident within the aneurysm after the device is deployed from the distal end of a catheter. The optional second or outer section has one or more array elements which are to be placed outside the aneurysm. The array elements typically extend from and are attached to an attachment area, often centrally located. The inventive device is at least partially formed of thin, usually metallic, sheets. After deployment of this retainer, the aneurysm may be partially filled with vaso-occlusive devices such as helically wound coils.

摘要翻译： 这是用于桥接脉管系统中的宽颈或窄颈动脉瘤颈部的装置。 它是一种本身可以用于桥接动脉瘤颈部或用于稳定其他血管闭塞装置的存在的装置，例如在该动脉瘤中螺旋缠绕的线圈。 包括的血管闭塞装置可以以各种不同的方式递送到动脉瘤，例如通过芯线，其通过可电解分离或机械可拆卸的关节连接到线圈。 血管闭塞装置也可以简单地推入动脉瘤。 动脉瘤颈桥还可以以各种方式递送，但是优选地附接到用于其展开的电解分离的接头。 本发明的颈桥可以包含一个或两个部分：放置在动脉瘤内的第一或内部部分和适当地放置在动脉瘤外部的任选的第二或外部部分。 第一部分通常具有多个阵列元件，其在装置从导管的远端部署之后旨在驻留在动脉瘤内。 可选的第二或外部部分具有一个或多个排列在动脉瘤外部的阵列元件。 阵列元件通常从附接区域延伸并且附接到通常位于中心的附接区域。 本发明的装置至少部分地由薄的，通常是金属的片材形成。 在展开该保持器之后，动脉瘤可以部分地填充有血管闭塞装置，例如螺旋卷绕的线圈。

公开(公告)号：US6030369A

公开(公告)日：2000-02-29

申请号：US887950

申请日：1997-07-03

申请人： Erik T. Engelson ,  Mark Carter

发明人： Erik T. Engelson ,  Mark Carter

IPC分类号： A61M25/00 ,  A61M25/16 ,  A61M5/00

CPC分类号： A61M25/0045 ,  A61M2025/0042 ,  A61M25/0009

摘要： This is a catheter having a shaft, the layers of which are coextruded in an intermittently changing pattern that produces particular mechanical and frictional properties in the structure. The outer layer of the catheter shaft is comprised of a material which has greater flexibility than the material which comprises the inner layer of the catheter shaft. The stiffer material which comprises the inner layer has frictional properties which facilitate guidewire passage and control. The invention includes the substituent shaft per se and a method of making the shaft.

摘要翻译： 这是具有轴的导管，其轴线以间歇变化的图案共挤出，在结构中产生特定的机械和摩擦特性。 导管轴的外层由与包括导管轴的内层的材料相比具有更大柔性的材料构成。 包含内层的更硬的材料具有促进导丝通过和控制的摩擦性能。 本发明包括取代轴本身以及制造轴的方法。

公开(公告)号：US6013084A

公开(公告)日：2000-01-11

申请号：US879408

申请日：1997-06-20

申请人： Christopher G. M. Ken ,  Joseph C. Eder ,  Clifford Teoh

发明人： Christopher G. M. Ken ,  Joseph C. Eder ,  Clifford Teoh

IPC分类号： A61B17/00 ,  A61B17/12 ,  A61B19/00 ,  A61F2/00 ,  A61M29/00

CPC分类号： A61B17/12022 ,  A61B17/12113 ,  A61B17/12145 ,  A61B17/1215 ,  A61B17/12154 ,  A61B2017/00867 ,  A61B2017/1205 ,  A61B2017/12063 ,  A61B2090/3937 ,  A61F2002/30093 ,  A61F2210/0019

摘要： This is an implantable vaso-occlusive device. It is typically a vaso-occlusive coil comprising a primary helically wound coil which may then be wound into a secondary shape. Central to the invention is the use of a stretch-resisting member extending through the lumen formed, which stretch-resisting member is fixedly attached, directly or indirectly, to the coil in at least two locations. The stretch-resisting member is preferably somewhat loose within the interior of the lumen so to prevent the coil from collapsing, binding, and therefore stiffening during passage of turns through the human body. The coil should bend easily. In some variations of the invention, the stretch-resisting member may be formed into coil tips at the ends of the coil using simple equipment such as soldering irons or the like. The tips are typically of the same diameter as is the coil body itself. This stretch-resisting member is for the primary purpose of preventing stretching of the coil during movement of that coil, e.g., by retrieval or repositioning after deployment. The device may have a self-forming secondary shape made from a pre-formed primary linear helically wound coil, although it need not have the secondary form. Desirably, the coil is extremely flexible and is controllaby released using a severable or mechanical joint such as an electrolytically detachable joint. External fibers may be attached to the device and affixed to the pre-formed linear member to increase thrombogenicity. The extremely flexible variation of the invention may be hydraulically delivered through the lumen of a catheter and is so flexible that it may be retrievably delivered therethrough a flow-directed catheter. The vaso-occlusive member may be also be covered with a fibrous braid. The device is typically introduced into the body through a catheter. The device is passed axially through the catheter sheath and assumes its secondary form upon exiting the catheter.

摘要翻译： 这是一种植入式血管闭塞装置。 它通常是包括初级螺旋缠绕线圈的血管闭塞线圈，然后可以将其缠绕成次级形状。 本发明的中心在于在至少两个位置上使用延伸穿过形成的内腔的拉伸抵抗构件，该拉伸抵抗构件直接地或间接地固定到线圈上。 拉伸阻力构件优选在内腔的内部稍微松动，从而防止线圈在匝穿过人体期间塌陷，结合并因此加强。 线圈应弯曲容易。 在本发明的一些变型中，可以使用诸如烙铁等的简单设备在线圈的端部处形成线圈尖端。 尖端通常具有与线圈体本身相同的直径。 该抗拉伸构件的主要目的是防止在线圈移动过程中线圈的拉伸，例如通过在展开后的取回或重新定位。 该装置可以具有由预先形成的初级线性螺旋缠绕线圈制成的自成形次级形状，尽管它不需要具有二次形式。 理想地，线圈非常柔软，并且使用可分离或机械接头（例如电解可拆卸接头）进行控制释放。 外部纤维可以附着到装置上并固定到预先形成的线性构件上以增加血栓形成。 本发明的极其灵活的变化可以通过导管的内腔液压输送，并且是如此柔性的，使得其可被可逆地递送通过其中的导向导管。 血管闭塞性构件也可以用纤维编织物覆盖。 该装置通常通过导管引入身体。 该装置轴向穿过导管护套，并在离开导管时呈现其次级形式。