公开(公告)号：US6036720A

公开(公告)日：2000-03-14

申请号：US990314

申请日：1997-12-15

申请人： Robert M. Abrams ,  Daniel R. Kurz

发明人： Robert M. Abrams ,  Daniel R. Kurz

IPC分类号： A61B17/12 ,  A61B17/08

CPC分类号： A61B17/12022 ,  A61B17/12113 ,  A61B17/1214 ,  A61B17/12172 ,  A61B2017/12063

摘要： This is a device for bridging the necks of wide-necked or narrow-necked aneurysms in the vasculature. It is a device which may be used by itself to bridge the neck of an aneurysm or used to stabilize the presence of other vaso-occlusive devices such as helically wound coils in that aneurysm. The included vaso-occlusive devices may be delivered to the aneurysm in a variety of different ways, e.g., by a core wire which is linked to the coils by an electrolytically severable or mechanically detachable joint. The vaso-occlusive devices may also be simply pushed into the aneurysm. The aneurysm neck bridge may also be delivered in a variety of ways, but preferably is attached to an electrolytically severable joint for its deployment. The inventive neck bridge may contain one or two sections: a first or inner section to be placed within the aneurysm and an optional second or outer section suitably placed outside the aneurysm. The first section typically has a number of array elements which are intended to be resident within the aneurysm after the device is deployed from the distal end of a catheter. The optional second or outer section has one or more array elements which are to be placed outside the aneurysm. The array elements typically extend from and are attached to an attachment area, often centrally located. The inventive device is at least partially formed of thin, usually metallic, sheets. After deployment of this retainer, the aneurysm may be partially filled with vaso-occlusive devices such as helically wound coils.

摘要翻译： 这是用于桥接脉管系统中的宽颈或窄颈动脉瘤颈部的装置。 它是一种本身可以用于桥接动脉瘤颈部或用于稳定其他血管闭塞装置的存在的装置，例如在该动脉瘤中螺旋缠绕的线圈。 包括的血管闭塞装置可以以各种不同的方式递送到动脉瘤，例如通过芯线，其通过可电解分离或机械可拆卸的关节连接到线圈。 血管闭塞装置也可以简单地推入动脉瘤。 动脉瘤颈桥还可以以各种方式递送，但是优选地附接到用于其展开的电解分离的接头。 本发明的颈桥可以包含一个或两个部分：放置在动脉瘤内的第一或内部部分和适当地放置在动脉瘤外部的任选的第二或外部部分。 第一部分通常具有多个阵列元件，其在装置从导管的远端部署之后旨在驻留在动脉瘤内。 可选的第二或外部部分具有一个或多个排列在动脉瘤外部的阵列元件。 阵列元件通常从附接区域延伸并且附接到通常位于中心的附接区域。 本发明的装置至少部分地由薄的，通常是金属的片材形成。 在展开该保持器之后，动脉瘤可以部分地填充有血管闭塞装置，例如螺旋卷绕的线圈。

公开(公告)号：US08529619B2

公开(公告)日：2013-09-10

申请号：US13181357

申请日：2011-07-12

申请人： Robert M. Abrams

发明人： Robert M. Abrams

IPC分类号： A61F2/84

CPC分类号： A61F2/07 ,  A61B17/12022 ,  A61B17/12109 ,  A61B17/12113 ,  A61B17/12168 ,  A61B2017/1205 ,  A61B2017/12063 ,  A61F2/88 ,  A61F2/95 ,  A61F2002/075 ,  A61F2230/008

摘要： An endoprosthesis cover may be attached to the distal end of a delivery device. The cover may be generally cylindrical in shape and may have a lumen through it. An endoprosthesis may then be covered as it is delivered to a treatment site.

摘要翻译： 内置假体盖可以附接到输送装置的远端。 盖可以是大致圆柱形的并且可以具有通过其的内腔。 然后可以在将内置假体递送至治疗部位时予以覆盖。

公开(公告)号：US08372062B2

公开(公告)日：2013-02-12

申请号：US13586280

申请日：2012-08-15

申请人： Richard Murphy ,  Michael P. Wallace ,  Tri Tran ,  Kim Nguyen ,  Hanh Ho ,  My Doan ,  Robert M. Abrams ,  Harold F. Carrison

发明人： Richard Murphy ,  Michael P. Wallace ,  Tri Tran ,  Kim Nguyen ,  Hanh Ho ,  My Doan ,  Robert M. Abrams ,  Harold F. Carrison

IPC分类号： A61B17/00

CPC分类号： A61B17/12113 ,  A61B17/12022 ,  A61B17/1214 ,  A61B17/12168 ,  A61B17/12172 ,  A61B90/39 ,  A61B2017/1205 ,  A61B2017/12063

摘要： In one embodiment, a neck bridge for bridging the neck of an aneurysm includes a junction region, a number of radially extending array elements attached to the junction region, and a cover attached to one or both of the junction region and an array element. The array elements are configured to be positioned within the aneurysm after the neck bridge is deployed from a delivery device. In a second embodiment, the neck bridge includes a junction region and a braided or mesh-like structure secured to the junction region. The braided or mesh-like structure is made from an elastic material.

公开(公告)号：US08303616B2

公开(公告)日：2012-11-06

申请号：US11028808

申请日：2005-01-03

申请人： Robert M. Abrams ,  Elaine Lee

发明人： Robert M. Abrams ,  Elaine Lee

IPC分类号： A61M29/00

CPC分类号： G06Q10/00 ,  A61F2/95 ,  A61F2002/9511 ,  G06F19/00 ,  G06Q50/22 ,  G06Q50/24

摘要： A medical device delivery system comprises a catheter having a catheter shaft with a proximal region and a distal region. The catheter shaft has a pull wire lumen therein. An expandable medical device is disposed about medical device receiving region of the catheter shaft. The expandable medical device has a reduced configuration and an expanded configuration. The system further comprises a retractable retaining wire, at least a portion of which is coiled about the expandable medical device and retains the expandable medical device in the reduced configuration. One end of the retractable retaining wire terminates in a pull-wire. The pull-wire extends into the pull-wire lumen to the proximal region of the catheter shaft.

摘要翻译： 医疗装置输送系统包括具有导管轴的导管，其具有近端区域和远端区域。 导管轴在其中具有拉丝腔。 可扩张医疗装置设置在导管轴的医疗装置接收区域周围。 可扩展医疗设备具有减小的配置和扩展配置。 该系统进一步包括可缩回保持线，其至少一部分围绕可扩张医疗装置卷绕并将可扩张医疗装置保持在减小的构型。 可伸缩保持线的一端终止于拉线。 拉线延伸到拉线管腔到导管轴的近端区域。

公开(公告)号：US20090124978A1

公开(公告)日：2009-05-14

申请号：US12353112

申请日：2009-01-13

申请人： Robert M. Abrams ,  Michael P. Wallace

发明人： Robert M. Abrams ,  Michael P. Wallace

IPC分类号： A61B17/34

CPC分类号： A61M25/0662 ,  A61M25/10 ,  A61M2025/0006 ,  A61M2025/0293 ,  A61M2025/0681 ,  A61M2025/09125 ,  A61M2025/1063

摘要： An apparatus for accessing a site within a body includes a cannula and an elongate member. The cannula has a proximal end, a distal end, and a lumen extending therebetween. The elongate member has a distal end configured for insertion into the lumen, wherein the distal end of the elongate member is attachable to and releasable from the distal end of the cannula. A method for accessing a site within a body includes inserting a distal end of an elongate member into a lumen of a cannula, detachably attaching the distal end of the elongate member to the cannula, and steering a distal end of the cannula to a desired site using the elongate member.

摘要翻译： 用于进入体内部位的装置包括套管和细长构件。 套管具有近端，远端和在其间延伸的内腔。 细长构件具有构造成用于插入内腔的远端，其中细长构件的远端可附接到插管的远端并且可从插管的远端释放。 用于访问体内部位的方法包括将细长构件的远端插入套管的内腔，将细长构件的远端可拆卸地连接到套管上，并将套管的远端转向所需位置 使用细长构件。

公开(公告)号：US06682608B2

公开(公告)日：2004-01-27

申请号：US10117155

申请日：2002-04-05

申请人： Robert M. Abrams ,  Sepehr Fariabi

发明人： Robert M. Abrams ,  Sepehr Fariabi

IPC分类号： C22C1903

CPC分类号： A61L31/14 ,  A61L31/022 ,  A61L2400/16 ,  A61M25/09 ,  A61M2025/09008 ,  A61M2025/09083 ,  A61M2025/09141 ,  A61M2025/09175 ,  A61M2205/0266 ,  C22C14/00 ,  C22C30/00 ,  C22F1/006

摘要： An improved guiding member for use within a body lumen having a unique combination of superelastic characteristics. The superelastic alloy material has a composition consisting of about 30% to about 52% (atomic) titanium, and about 38% to 52% nickel and may have one or more elements selected from the group consisting of iron, cobalt, platinum, palladium, vanadium, copper, zirconium, hafnium and niobium. The alloy material is subjected to thermomechanical processing which includes a final cold working of about 10 to about 75% and then a heat treatment at a temperature between about 450° and about 600° C. and preferably about 475° to about 550° C. Before the heat treatment the cold worked alloy material is preferably subjected to mechanical straightening. The alloy material is preferably subjected to stresses equal to about 5 to about 50% of the room temperature ultimate yield stress of the material during the thermal treatment. The guiding member using such improved material exhibits a stress-induced austenite-to-martensite phase transformation at an exceptionally high constant yield strength of over 90 ksi for solid members and over 70 ksi for tubular members with a broad recoverable strain of at least about 4% during the phase transformation. An essentially whip free product is obtained.

摘要翻译： 改进的引导构件用于体腔内，具有超弹性特征的独特组合。 超弹性合金材料具有由约30％至约52％（原子）钛和约38％至52％的镍组成的组成，并且可以具有一种或多种选自铁，钴，铂，钯， 钒，铜，锆，铪和铌。 对合金材料进行热机械加工，其包括约10至约75％的最终冷加工，然后在约450℃至约600℃，优选约475℃至约550℃的温度下进行热处理。 在热处理之前，冷加工合金材料优选进行机械矫直。 合金材料优选在热处理期间受到等于材料的室温极限屈服应力的约5至约50％的应力。 使用这种改进的材料的引导构件在固体构件的超过90ksi的异常高的恒定屈服强度下显示出应力诱发的奥氏体 - 马氏体相变，对于具有至少约4的广泛可恢复应变的管状构件，具有超过70ksi ％相变。 获得基本上无鞭状产品。

公开(公告)号：US06461453B1

公开(公告)日：2002-10-08

申请号：US09589646

申请日：2000-06-07

申请人： Robert M. Abrams ,  Sepehr Fariabi

发明人： Robert M. Abrams ,  Sepehr Fariabi

IPC分类号： C22C1903

CPC分类号： A61M25/09 ,  A61L31/022 ,  A61L31/14 ,  A61L2400/16 ,  A61M2025/09008 ,  A61M2025/09083 ,  A61M2025/09141 ,  A61M2025/09175 ,  A61M2205/0266 ,  C22C14/00 ,  C22C30/00 ,  C22F1/006

摘要： An improved guiding member for use within a body lumen having a unique combination of superelastic characteristics. The superelastic alloy material has a composition consisting of about 30% to about 52% (atomic) titanium, and about 38% to 52% nickel and may have one or more elements selected from the group consisting of iron, cobalt, platinum, palladium, vanadium, copper, zirconium, hafnium and niobium. The alloy material is subjected to thermomechanical processing which includes a final cold working of about 10 to about 75% and then a heat treatment at a temperature between about 450° and about 600° C. and preferably about 475° to about 550° C. Before the heat treatment the cold worked alloy material is preferably subjected to mechanical straightening. The alloy material is preferably subjected to stresses equal to about 5 to about 50% of the room temperature ultimate yield stress of the material during the thermal treatment. The guiding member using such improved material exhibits a stress-induced austenite-to-martensite phase transformation at an exceptionally high constant yield strength of over 90 ksi for solid members and over 70 ksi for tubular members with a broad recoverable strain of at least about 4% during the phase transformation. An essentially whip free product is obtained.

摘要翻译： 改进的引导构件用于体腔内，具有超弹性特征的独特组合。 超弹性合金材料具有由约30％至约52％（原子）钛和约38％至52％的镍组成的组成，并且可以具有一种或多种选自铁，钴，铂，钯， 钒，铜，锆，铪和铌。 对合金材料进行热机械加工，其包括约10至约75％的最终冷加工，然后在约450℃至约600℃，优选约475℃至约550℃的温度下进行热处理。 在热处理之前，冷加工合金材料优选进行机械矫直。 合金材料优选在热处理期间受到等于材料的室温极限屈服应力的约5至约50％的应力。 使用这种改进的材料的引导构件在固体构件的超过90ksi的异常高的恒定屈服强度下显示出应力诱发的奥氏体 - 马氏体相变，对于具有至少约4的广泛可恢复应变的管状构件，具有超过70ksi ％相变。 获得基本上无鞭状产品。

公开(公告)号：US06165292A

公开(公告)日：2000-12-26

申请号：US484218

申请日：1995-06-07

申请人： Robert M. Abrams ,  Sepehr Fariabi

发明人： Robert M. Abrams ,  Sepehr Fariabi

IPC分类号： A61L31/02 ,  A61M25/09 ,  C22C14/00 ,  C22C30/00 ,  C22F1/00 ,  C22F1/10 ,  C22K1/00

CPC分类号： A61M25/09 ,  A61L31/022 ,  A61L31/14 ,  A61L2400/16 ,  A61M2025/09008 ,  A61M2025/09083 ,  A61M2025/09141 ,  A61M2025/09175 ,  A61M2205/0266 ,  C22C14/00 ,  C22C30/00 ,  C22F1/006

摘要： An improved guiding member for use within a body lumen having a unique combination of superelastic characteristics. The superelastic alloy material has a composition consisting of about 30% to about 52% (atomic) titanium, and about 38% to 52% nickel and may have one or more elements selected from the group consisting of iron, cobalt, platinum, palladium, vanadium, copper, zirconium, hafnium and niobium. The alloy material is subjected to thermomechanical processing which includes a final cold working of about 10 to about 75% and then a heat treatment at a temperature between about 450.degree. and about 600.degree. C. and preferably about 475.degree. to about 550.degree. C. Before the heat treatment the cold worked alloy material is preferably subjected to mechanical straightening. The alloy material is preferably subjected to stresses equal to about 5 to about 50% of the room temperature ultimate yield stress of the material during the thermal treatment. The guiding member using such improved material exhibits a stress-induced austenite-to-martensite phase transformation at an exceptionally high constant yield strength of over 90 ksi for solid members and over 70 ksi for tubular members with a broad recoverable strain of at least about 4% during the phase transformation. An essentially whip free product is obtained.

摘要翻译： 改进的引导构件用于体腔内，具有超弹性特征的独特组合。 超弹性合金材料具有由约30％至约52％（原子）钛和约38％至52％的镍组成的组成，并且可以具有一种或多种选自铁，钴，铂，钯， 钒，铜，锆，铪和铌。 对合金材料进行热机械加工，其包括约10至约75％的最终冷加工，然后在约450℃至约600℃，优选约475℃至约550℃的温度下进行热处理。 在热处理之前，冷加工合金材料优选进行机械矫直。 合金材料优选在热处理期间受到等于材料的室温极限屈服应力的约5至约50％的应力。 使用这种改进的材料的引导构件在固体构件的超过90ksi的异常高的恒定屈服强度下显示出应力诱发的奥氏体 - 马氏体相变，对于具有至少约4的广泛可恢复应变的管状构件，具有超过70ksi ％相变。 获得基本上无鞭状产品。

公开(公告)号：US5637089A

公开(公告)日：1997-06-10

申请号：US598639

申请日：1996-02-12

申请人： Robert M. Abrams ,  Sepehr Fariabi

发明人： Robert M. Abrams ,  Sepehr Fariabi

IPC分类号： A61L31/02 ,  A61M25/09 ,  C22C14/00 ,  C22C30/00 ,  C22F1/00 ,  A61M37/00

CPC分类号： A61M25/09 ,  A61L31/022 ,  A61L31/14 ,  C22C14/00 ,  C22C30/00 ,  C22F1/006 ,  A61L2400/16 ,  A61M2025/09008 ,  A61M2025/09083 ,  A61M2025/09141 ,  A61M2025/09175 ,  A61M2205/0266

摘要： An improved guiding member for use within a body lumen having a unique combination of superelastic characteristics. The superelastic alloy material has a composition consisting of about 30% to about 52% (atomic) titanium, and about 38% to 52% nickel and may have one or more elements selected from the group consisting of iron, cobalt, platinum, palladium, vanadium, copper, zirconium, hafnium and niobium. The alloy material is subjected to thermomechanical processing which includes a final cold working of about 10 to about 75% and then a heat treatment at a temperature between about 450.degree. and about 600.degree. C. and preferably about 475.degree. to about 550.degree. C. Before the heat treatment the cold worked alloy material is preferably subjected to mechanical straightening. The alloy material is preferably subjected to stresses equal to about 5 to about 50% of the room temperature ultimate yield stress of the material during the thermal treatment. The guiding member using such improved material exhibits a stress-induced austenite-to-martensite phase transformation at an exceptionally high constant yield strength of over 90 ksi for solid members and over 70 ksi for tubular members with a broad recoverable strain of at least about 4% during the phase transformation. An essentially whip free product is obtained.

摘要翻译： 改进的引导构件用于体腔内，具有超弹性特征的独特组合。 超弹性合金材料具有由约30％至约52％（原子）钛和约38％至52％的镍组成的组成，并且可以具有一种或多种选自铁，钴，铂，钯， 钒，铜，锆，铪和铌。 对合金材料进行热机械加工，其包括约10至约75％的最终冷加工，然后在约450℃至约600℃，优选约475℃至约550℃的温度下进行热处理。 在热处理之前，冷加工合金材料优选进行机械矫直。 合金材料优选在热处理期间受到等于材料的室温极限屈服应力的约5至约50％的应力。 使用这种改进的材料的引导构件在固体构件的超过90ksi的异常高的恒定屈服强度下显示出应力诱发的奥氏体 - 马氏体相变，对于具有至少约4的广泛可恢复应变的管状构件，具有超过70ksi ％相变。 获得基本上无鞭状产品。

公开(公告)号：US5492119A

公开(公告)日：1996-02-20

申请号：US172039

申请日：1993-12-22

申请人： Robert M. Abrams

发明人： Robert M. Abrams

IPC分类号： A61N1/05 ,  A61B5/04

CPC分类号： A61N1/0573

摘要： Electrophysiology catheter apparatus including at least one retractable control wire with a preformed curved resilient foot formed at the distal extremity, slidably advanced and retracted within a longitudinal lumen of a catheter tube for controllably anchoring to a selected endocardial heart tissue. The proximal end of the control wire is formed with a handle to be grasped to slidably advance the preformed resilient foot beyond the distal tip of a catheter to project laterally to contact the adjacent tissue.

摘要翻译： 电生理学导管装置，其包括至少一个可缩回的控制线，其具有形成在远端的预成形的弯曲弹性脚，可滑动地前进并在导管管的纵向内腔内缩回，用于可控地锚定到选定的心内膜心脏组织。 控制线的近端形成有待抓握的手柄，以将预成型的弹性脚可滑动地推进超过导管的远侧末端以横向突出以接触邻近的组织。