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公开(公告)号:US20110311988A1
公开(公告)日:2011-12-22
申请号:US13142925
申请日:2009-12-31
IPC分类号: G01N33/566 , G01N33/559 , G01N27/447 , C12Q1/02 , G01N33/50
CPC分类号: G01N33/5308 , G01N2400/40 , G01N2800/042 , G01N2800/56 , Y10T436/143333
摘要: Provided herein are processes of detecting and quantifying the number of polymer end groups in a sample. In particular instances provided herein are processes of detecting.
摘要翻译: 本文提供了检测和定量样品中聚合物端基数目的方法。 本文提供的特定情况是检测过程。
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公开(公告)号:US08232073B2
公开(公告)日:2012-07-31
申请号:US12649110
申请日:2009-12-29
CPC分类号: C12Q1/527 , C12Q1/34 , C12Q1/40 , G01N33/6893 , G01N2333/924 , G01N2400/00 , G01N2800/042 , G01N2800/52
摘要: Provided herein are methods of diagnosing or monitoring the treatment of abnormal glycan accumulation or a disorder associated with abnormal glycan accumulation.
摘要翻译: 本文提供了诊断或监测异常聚糖积聚的治疗或与异常聚糖累积相关的病症的方法。
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公开(公告)号:US08183003B2
公开(公告)日:2012-05-22
申请号:US13142925
申请日:2009-12-31
CPC分类号: G01N33/5308 , G01N2400/40 , G01N2800/042 , G01N2800/56 , Y10T436/143333
摘要: Provided herein are processes of detecting and quantifying the number of polymer end groups in a sample. In particular instances provided herein are processes of detecting.
摘要翻译: 本文提供了检测和定量样品中聚合物端基数目的方法。 本文提供的特定情况是检测过程。
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公开(公告)号:US20130217056A1
公开(公告)日:2013-08-22
申请号:US13629321
申请日:2012-09-27
IPC分类号: C12Q1/34
CPC分类号: G01N33/5308 , C12Q1/34 , C12Q1/40 , C12Q1/42 , C12Q1/527 , G01N33/6893 , G01N2333/924 , G01N2333/988 , G01N2400/00 , G01N2400/10 , G01N2800/04 , G01N2800/042 , G01N2800/044 , G01N2800/28 , G01N2800/52 , G01N2800/56
摘要: Provided herein are methods of diagnosing or monitoring the treatment of abnormal glycan accumulation or a disorder associated with abnormal glycan accumulation.
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公开(公告)号:US20100184013A1
公开(公告)日:2010-07-22
申请号:US12649094
申请日:2009-12-29
IPC分类号: C12Q1/00
CPC分类号: C12Q1/527 , A61K31/702 , C07H3/04 , C07H3/06 , C07H5/06 , C07H7/033 , C07H11/00 , C07H13/04 , G01N33/66 , G01N2333/988 , G01N2400/40 , G01N2800/042 , G01N2800/52 , G01N2800/7071
摘要: Provided herein are processes for detecting oligosaccharides in a biological sample. In specific instances, the biological sample is provided from an individual suffering from a disorder associated with abnormal glycosaminoglycan accumulation.
摘要翻译: 本文提供了检测生物样品中寡糖的方法。 在具体情况下,生物样品由患有与异常糖胺聚糖累积相关的病症的个体提供。
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公开(公告)号:US20100248365A1
公开(公告)日:2010-09-30
申请号:US12748948
申请日:2010-03-29
CPC分类号: C12P21/005
摘要: Provided herein are ganglioside synthesis inhibitors, including modulators of ganglioside glycosylation.
摘要翻译: 提供神经节苷脂合成抑制剂,包括神经节苷脂糖基化的调节剂。
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公开(公告)号:US20100048638A1
公开(公告)日:2010-02-25
申请号:US12496548
申请日:2009-07-01
申请人: Brett E. CRAWFORD , Charles A. GLASS , Jillian R. BROWN , Robert G. WITT , Benedikt VOLLRATH , Jay LICHTER
发明人: Brett E. CRAWFORD , Charles A. GLASS , Jillian R. BROWN , Robert G. WITT , Benedikt VOLLRATH , Jay LICHTER
IPC分类号: A61K31/4439 , C07D401/04 , A61P35/00
CPC分类号: A61K31/5377 , A61K31/00 , A61K31/4439 , A61K31/4709 , C07K1/1077 , C07K5/08
摘要: Provided herein are heparan sulfate inhibitors, including modulators of heparan sulfate glycosylation, heparan sulfate sulfation, and/or heparan sulfate epimerization.
摘要翻译: 本文提供硫酸乙酰肝素抑制剂,包括硫酸乙酰肝素糖基化,硫酸乙酰肝素硫酸化和/或硫酸乙酰肝素差向异构化的调节剂。
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公开(公告)号:US20130149729A1
公开(公告)日:2013-06-13
申请号:US13550106
申请日:2012-07-16
CPC分类号: C12Q1/527 , C12Q1/34 , C12Q1/40 , G01N33/6893 , G01N2333/924 , G01N2400/00 , G01N2800/042 , G01N2800/52
摘要: Provided herein are methods of diagnosing or monitoring the treatment of abnormal glycan accumulation or a disorder associated with abnormal glycan accumulation.
摘要翻译: 本文提供了诊断或监测异常聚糖积聚的治疗或与异常聚糖累积相关的病症的方法。
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公开(公告)号:US20120009616A1
公开(公告)日:2012-01-12
申请号:US13142959
申请日:2009-12-31
IPC分类号: C12Q1/527
CPC分类号: G01N33/50 , G01N33/66 , G01N2400/40 , G01N2800/042
摘要: Provided herein are processes for detecting oligosaccharides in a biological sample. In specific instances, the biological sample is provided from an individual suffering from a disorder associated with abnormal glycosaminoglycan accumulation.
摘要翻译: 本文提供了检测生物样品中寡糖的方法。 在具体情况下,生物样品由患有与异常糖胺聚糖累积相关的病症的个体提供。
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公开(公告)号:US20100173337A1
公开(公告)日:2010-07-08
申请号:US12649110
申请日:2009-12-29
CPC分类号: C12Q1/527 , C12Q1/34 , C12Q1/40 , G01N33/6893 , G01N2333/924 , G01N2400/00 , G01N2800/042 , G01N2800/52
摘要: Provided herein are methods of diagnosing or monitoring the treatment of abnormal glycan accumulation or a disorder associated with abnormal glycan accumulation.
摘要翻译: 本文提供了诊断或监测异常聚糖积聚的治疗或与异常聚糖累积相关的病症的方法。
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