Human vanilloid receptor VR3 protein
    4.
    发明授权
    Human vanilloid receptor VR3 protein 有权
    人类香草素受体VR3蛋白

    公开(公告)号:US07186803B2

    公开(公告)日:2007-03-06

    申请号:US10985156

    申请日:2004-11-10

    CPC分类号: C07K14/705 A61K38/00

    摘要: DNA encoding human VR1 receptor has been cloned and characterized. The recombinant protein is capable of forming biologically active protein. The cDNA's have been expressed in recombinant host cells that produce active recombinant protein. The recombinant protein is also purified from the recombinant host cells. In addition, the recombinant host cells are utilized to establish a method for identifying modulators of the receptor activity, and receptor modulators are identified.

    摘要翻译: 编码人VR1受体的DNA已被克隆和表征。 重组蛋白能够形成生物活性蛋白。 cDNA已经在产生活性重组蛋白的重组宿主细胞中表达。 重组蛋白也从重组宿主细胞中纯化。 此外,重组宿主细胞用于建立识别受体活性调节剂的方法,并鉴定受体调节剂。

    DNA encoding human vanilloid receptor VR3
    8.
    发明授权
    DNA encoding human vanilloid receptor VR3 有权
    编码人类香草素受体VR3的DNA

    公开(公告)号:US06455278B1

    公开(公告)日:2002-09-24

    申请号:US09500123

    申请日:2000-02-08

    IPC分类号: C12N1512

    CPC分类号: C07K14/705 A61K38/00

    摘要: DNA encoding human VR1 receptor has been cloned and characterized. The recombinant protein is capable of forming biologically active protein. The cDNA's have been expressed in recombinant host cells that produce active recombinant protein. The recombinant protein is also purified from the recombinant host cells. In addition, the recombinant host cells are utilized to establish a method for identifying modulators of the receptor activity, and receptor modulators are identified.

    摘要翻译: 编码人VR1受体的DNA已被克隆和表征。 重组蛋白能够形成生物活性蛋白。 cDNA已经在产生活性重组蛋白的重组宿主细胞中表达。 重组蛋白也从重组宿主细胞中纯化。 此外,重组宿主细胞用于建立识别受体活性调节剂的方法,并鉴定受体调节剂。