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公开(公告)号：US12102384B2
公开(公告)日：2024-10-01
申请号：US17094622
申请日：2020-11-10
申请人： Bolt Medical, Inc.
CPC分类号： A61B18/26 , A61B2017/00154 , A61B2017/00539 , A61B2018/00196 , A61B2018/0022 , A61B2018/266 , A61M25/0113 , A61M2025/0681
摘要： A catheter system for treating a treatment site within or adjacent to a blood vessel within a body of a patient, the treatment site having a proximal region and a distal region, includes an energy source, a guide shaft, and an energy guide. The energy source generates energy. The guide shaft is positionable adjacent to the treatment site. The energy guide receives energy from the energy source. The energy guide is movably coupled to the guide shaft. The energy guide includes a guide distal end that is configured to be positioned adjacent to the treatment site. The guide distal end of the energy guide is selectively movable relative to the guide shaft and adjacent to and between the proximal region and the distal region of the treatment site while the energy guide receives energy from the energy source.
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公开(公告)号：US20230347182A1
公开(公告)日：2023-11-02
申请号：US18217220
申请日：2023-06-30
CPC分类号： A61N7/00 , A61B18/26 , A61N2007/0026 , A61B2018/266
摘要： Provided herein are noninvasive stimulation methods and apparatus for the treatment of injury to tissues using a novel pulsed laser system that combines the benefits of near-infrared laser light and optoacoustic waves. In certain embodiments, short, high-energy laser light pulses generate low intensity ultrasound waves that travel deep into brain tissues to stimulate neural function and treat neurological dysfunctions. In certain embodiments, a patient interface is provided wherein optoacoustic waves are produced by a plurality of optical absorbers overlying all of a plurality of optical fibers while in other embodiments optoacoustic waves are generated both inside the tissue and outside the tissue via a plurality of optical absorbers overlying some but not all of the optical fibers thus enabling an option of varying proportions of optoacoustic waves generated inside and outside of tissue.
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公开(公告)号：US11730979B2
公开(公告)日：2023-08-22
申请号：US16339032
申请日：2017-10-05
CPC分类号： A61N7/00 , A61B18/26 , A61B2018/266 , A61N2007/0026
摘要： Provided herein are noninvasive stimulation methods and apparatus for the treatment of injury to tissues using a novel pulsed laser system that combines the benefits of near-infrared laser light and optoacoustic waves. In certain embodiments, short, high-energy laser light pulses generate low intensity ultrasound waves that travel deep into brain tissues to stimulate neural function and treat neurological dysfunctions. In certain embodiments, a patient interface is provided wherein optoacoustic waves are produced by a plurality of optical absorbers overlying all of a plurality of optical fibers while in other embodiments optoacoustic waves are generated both inside the tissue and outside the tissue via a plurality of optical absorbers overlying some but not all of the optical fibers thus enabling an option of varying proportions of optoacoustic waves generated inside and outside of tissue.
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公开(公告)号：US09999784B2
公开(公告)日：2018-06-19
申请号：US14397884
申请日：2013-06-25
CPC分类号： A61N5/062 , A61B18/203 , A61B18/26 , A61B2018/00452 , A61B2018/0047 , A61B2018/00577 , A61B2018/202 , A61B2018/263 , A61B2018/266 , A61M5/14248 , A61M37/00 , A61M2005/3022 , A61M2037/0007 , A61M2205/058 , A61N5/0616
摘要： A system (101) for treatment of an epithelial tissue layer (3) is provided. The system comprises a reservoir (107), for containing an amount of a flowable medium, arranged to enable the medium, when contained in the reservoir, to be in contact with a surface (5) of the epithelial tissue layer, a light source (109) for generating a laser beam (11) during at least a predetermined pulse time, and an optical system for focusing the laser beam into a focal spot (15), and for positioning the focal spot in a target position. The target position of the focal spot is within the reservoir and within the medium, when contained in the reservoir, and the dimension of the focal spot and the power of the generated laser beam are such that, in the focal spot, the laser beam has a power density, which is above the characteristic threshold value for the medium, above which, for the predetermined pulse time, a laser induced optical breakdown event occurs in the medium. A method for treatment of an epithelial tissue layer is also provided.
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公开(公告)号：US20140277002A1
公开(公告)日：2014-09-18
申请号：US13800214
申请日：2013-03-13
发明人： Kenneth P. Grace
IPC分类号： A61B17/22
CPC分类号： A61M25/104 , A61B17/22 , A61B17/22012 , A61B17/2202 , A61B17/320725 , A61B18/26 , A61B2017/22001 , A61B2017/22014 , A61B2017/22061 , A61B2017/22062 , A61B2017/22081 , A61B2018/263 , A61B2018/266 , A61M2025/1088 , A61M2025/109
摘要： A dilation balloon is wrapped in one or more patterns with a wire or braided material having diamond abrasive or other abrasive material bonded thereto. The wire or braided material is vibrated in one or more ways to enhance the cutting action of the wire abrasive. The wire abrasive may be vibrated using high, low, or even ultrasonic waves transmitted to the wire abrasive via local or remote methods. Alternatively, the dilation balloon may be dilated with a contrast media that exhibits a high absorption to laser light. The contrast material is lased with a laser fiber or fibers inserted into the balloon interior, creating a substantial shockwave that vibrates the balloon and assists in the cracking or abrading of the surrounding plaque in contact with the dilation balloon. The cutting balloon may employ the abrasive coated wires described above or cutting blades.
摘要翻译： 膨胀气球用一种或多种具有金刚石研磨剂或其他研磨材料的丝线或编织材料包裹在一起或多个图案中。 线或编织材料以一种或多种方式振动以增强线磨料的切割作用。 线磨料可以使用通过局部或远程方法传送到钢丝磨料的高，低或甚至超声波振动。 或者，扩张气囊可以用对激光表现出高吸收的造影剂来扩张。 对比材料以激光纤维或插入球囊内部的纤维为基础，产生振动球囊的相当大的冲击波，并有助于与膨胀气球接触的周围斑块的开裂或研磨。 切割气球可以使用上述磨料涂层钢丝或切割刀片。
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公开(公告)号：US06203537B1
公开(公告)日：2001-03-20
申请号：US09244850
申请日：1999-02-04
申请人： Sorin Adrian
发明人： Sorin Adrian
IPC分类号： A61B1700
CPC分类号： A61B18/26 , A61B2018/0019 , A61B2018/00196 , A61B2018/266
摘要： An acoustic ablation catheter includes a mass cap mounted by a spring at the distal end of the catheter, to thereby form a structure capable of axial motion with a resonant frequency. The mass cap defines an aperture which may be used for a guide wire, for aspiration/infusion, or both. Acoustic motion of the resonant structure is generated by sources of laser light spaced about the distal end of the flexible portion of the catheter body, which produce laser light beams which produce microexplosions adjacent the proximal end of the mass cap. The sources of laser light beams may be laser chips located at the distal end of the body, or they may be the distal ends of optical fibers extending through the body from laser light generators outside the catheter itself. In one advantageous embodiment, relative motion is introduced between the mass cap and the light beams, so that erosion is distributed over a track. At least that portion of the mass cap upon which the laser light pulses impinge is made from titanium.
摘要翻译： 声消融导管包括通过弹簧在导管的远端安装的质量帽，从而形成能够以共振频率轴向运动的结构。 质量帽限定可用于导丝，用于抽吸/输注或两者的孔。 谐振结构的声音运动由导管主体的柔性部分的远端间隔开的激光源产生，其产生产生邻近质量帽的近端的微小爆炸物的激光束。 激光束的源可以是位于身体远端处的激光芯片，或者它们可以是从导管本身之外的激光发生器延伸穿过身体的光纤的远端。 在一个有利的实施例中，在质量帽和光束之间引入相对运动，使得侵蚀分布在轨道上。 至少激光光脉冲撞击的质量帽的那部分由钛制成。
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公开(公告)号：US5425735A
公开(公告)日：1995-06-20
申请号：US129554
申请日：1993-09-22
申请人： David I. Rosen , Charles Shibilia
发明人： David I. Rosen , Charles Shibilia
CPC分类号： A61B17/22022 , A61B18/26 , A61B17/3207 , A61B2017/22038 , A61B2017/22091 , A61B2017/320008 , A61B2017/922 , A61B2017/928 , A61B2018/266 , A61B90/39
摘要： A shielded tip catheter for use with a pulsed energy source for fracturing deposits such as urinary and biliary stones and atherosclerotic plaque in the human body is disclosed. The flexible catheter has a shielded tip structure which is adapted for insertion through a fluid passage in a living body. The tip structure can contain an impact element, a scraping implement or a cutting implement. An energy source creates repeated rapid vapor expansions adjacent the element causing it to undergo repeated pulse like movements, imparting a series of high-velocity impulses to an adjacent deposit, thereby fracturing or cutting it. The energy source can be a laser with a fiber optic delivery system in the catheter terminating adjacent the impact element, or a spark generator with a conductor within the catheter to deliver a fluid vaporizing spark adjacent the element.
摘要翻译： 公开了一种用于压力沉积物的脉冲能量源的屏蔽尖端导管，例如尿液和胆石和动脉粥样硬化斑块在人体内。 柔性导管具有屏蔽的尖端结构，其适于插入生物体中的流体通道。 尖端结构可以包含冲击元件，刮削工具或切割工具。 能量源在元件附近产生重复的快速蒸气膨胀，使其经受重复的脉冲状运动，给相邻的沉积物施加一系列高速脉冲，从而压裂或切割它。 能量源可以是激光器，其中导管中的光纤输送系统在撞击元件附近终止，或火花发生器具有在导管内的导体，以输送邻近元件的流体蒸发火花。
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公开(公告)号：US20240099773A1
公开(公告)日：2024-03-28
申请号：US18470132
申请日：2023-09-19
发明人： Jon Schabert
CPC分类号： A61B18/26 , A61B17/22022 , A61B2017/22025 , A61B2017/22062 , A61B2018/0022 , A61B2018/266
摘要： A lithotripsy device includes an elongate body comprising a distal tip portion having an end surface that forms a non-zero angle with a longitudinal axis of the elongate body, a balloon circumferentially around a portion of the elongate body enclosing the end surface of the tip portion defining an interior configured to receive a fluid, and at least one emitter positioned at the end surface of the tip portion of the elongate body. The at least one emitter is configured to generate pressure waves in the fluid propagating through the balloon to disintegrate a calcified lesion. A method of using a lithotripsy device is also provided.
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公开(公告)号：US20180098779A1
公开(公告)日：2018-04-12
申请号：US15725161
申请日：2017-10-04
IPC分类号： A61B17/22
CPC分类号： A61B17/22004 , A61B17/22012 , A61B17/22022 , A61B18/26 , A61B2017/22025 , A61B2017/22079 , A61B2017/22098 , A61B2018/00369 , A61B2018/2211 , A61B2018/263 , A61B2018/266
摘要： Described herein are shock wave devices and methods for the treatment of calcified heart valves. One variation of a shock wave device may comprise an elongated flexible tube carried by a sheath. The tube may have a fluid input end, which may be located near a proximal end of the sheath. The tube may include a loop portion. The loop portion may be configured to be at least partially accommodated within a cusp of the heart valve. The tube may be fillable with a conductive fluid. In some variations, the shock wave device may include an array of electrode pairs associated with a plurality of wires positioned within the loop portion of a tube. The electrode pairs may be electrically connectable to a voltage source and configured to generate shock waves in the conductive fluid in response to voltage pulses.
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公开(公告)号：US09468500B2
公开(公告)日：2016-10-18
申请号：US11315546
申请日：2005-12-22
申请人： Gan Zhou
发明人： Gan Zhou
CPC分类号： A61B18/24 , A61B8/12 , A61B8/4483 , A61B2018/266 , A61B2090/3784 , G01S15/8965 , G10K15/046
摘要： A catheter and a console for a catheter. In one embodiment, the catheter includes: (1) a wall having a substantially annular cross-section and surrounding a bore, (2) a plurality of optical fibers associated with the wall and terminating at a distal end of the wall in end faces of differing, non-perpendicular orientation with respect to longitudinal axes of the plurality of optical fibers and (3) photoacoustic layers coupled to at least some of the end faces and configured to generate an ultrasonic signal in response to laser light transmitted along the plurality of optical fibers.
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