公开(公告)号：US20170281532A1

公开(公告)日：2017-10-05

申请号：US15490220

申请日：2017-04-18

申请人： Glaxo Group Limited ,  Shionogi and Co., Ltd

发明人： Toshiaki AOKI ,  Hiroki KUSANO ,  Xiangmin LIAO ,  Neil David PEARSON ,  Israil PENDRAK ,  Jun SATO ,  Reema K. THALJI ,  Kenji YAMAWAKI ,  Katsuki YOKOO

IPC分类号： C07D501/48 ,  C07D501/50 ,  C07D505/24 ,  A61K9/00

CPC分类号： C07D501/48 ,  A61K9/0019 ,  C07D501/50 ,  C07D505/24 ,  Y02A50/473

摘要： The compounds of the subject invention are related to 2-substituted cephem compounds, which have a wide antimicrobial spectrum, in particular exhibit potent antimicrobial activity against beta-lactamase producing Gram negative bacteria, and pharmaceutical compositions comprising the same.